Permetron Lotion belongs to Antiparasitic class of drug. It is used to treat scabies, a skin infection caused by microscopic insects that infest and irritate the skin. The insects (mites) and their eggs are killed by this treatment. To be sure you're using Permetron Lotion appropriately, read the directions that came with it. Before using it, make sure your skin is clean, dry, and cool. 8-14 hours after using this drug, you should thoroughly wash your entire body. Most people only need to take it once to treat their ailment, but if you do, wait at least 7 days before using it again. Itching may persist for a few weeks following scabies treatment. This is most likely an allergic reaction to the dead mites, not a warning that the treatment isn't working.