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Pimapexole 0.5 Tablet 10

Steris Healthcare

Strip of 10 Units

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MRP ~~₹105~~

₹52.39

₹10.5/Units

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Composition

Pramipexole (0.5 Mg)

Strength:

1 MG 0.5 MG

Pimapexole 0.5 Tablet is used in the management of symptoms associated with Parkinson's disease and restless legs syndrome (RLS) in adults. It falls under the category of dopamine agonist medications.

Before you start taking this medicine, it's essential to discuss your current health status with your doctor, including any ongoing medications or pre-existing conditions. If you experience side effects while on this medication, ensure to inform your doctor promptly. It's crucial to continue taking the medicine for the full duration prescribed by your doctor for optimal results.

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Pimapexole 0.5 Tablet is primarily used for:

Parkinson's disease
Restless legs syndrome (RLS) in adults

Directions for Use of Pimapexole 0.5 Tablet 10

Swallow the tablet as a whole, using a glass of water.
Avoid breaking, crushing, or chewing the tablet.
The medicine can be taken with or without food.
You should not stop taking this medicine abruptly. Always consult your doctor before deciding to discontinue.

Pimapexole 0.5 Tablet is taken orally.

Side Effects of Pimapexole 0.5 Tablet 10

The side effects of Pimapexole 0.5 Tablet include:

Nausea and vomiting
Constipation
Headache and dizziness
Fatigue
Insomnia or abnormal dreams

Managing the Side Effects:

Some side effects are temporary and generally harmless, which resolve on discontinuing Pimapexole 0.5 Tablet. However, if you experience severe side effects or worsening symptoms, please consult your doctor. Here are some suggestions to manage your side effects:

Drinking plenty of water can help manage constipation and dry mouth due to this medicine.
Resting and avoiding strenuous activities can help manage feelings of fatigue.

Pimapexole 0.5 Tablet contains the following component:

Pramipexole (0.5 mg): Pramipexole is a dopamine receptor agonist. It works by selectively activating dopamine D2 receptors, particularly the D3 subtype, in the brain's caudate-putamen region. This mimics the action of dopamine, a neurotransmitter that is deficient in Parkinson's disease, improving muscle control and reducing abnormal movements.

Pregnancy

Caution is advised while taking Pimapexole 0.5 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

It is not known if this medicine is excreted in breast milk. Consult your doctor before using this medicine while breastfeeding.

Alcohol

While taking Pimapexole 0.5 Tablet, it's important to be cautious about consuming alcohol as it can potentially worsen certain side effects.

Liver

If you have liver problems, discuss them with your doctor before starting Pimapexole 0.5 Tablet. This medicine could impact liver function, especially in patients with severe liver diseases.

Kidney

For those with kidney health issues, caution is advised before using Pimapexole 0.5 Tablet. Consult your doctor to evaluate if this medicine is suitable for you.

Using Machines & Driving

As this medicine can cause dizziness and fatigue as side effects, it might affect your ability to drive or operate machinery. Be cautious until you know how Pimapexole 0.5 Tablet affects you.

Allergy

If you're allergic to Pramipexole or any other inactive ingredients in Pimapexole 0.5 Tablet, avoid taking this medicine. It's best to consult with your doctor for alternatives.

Children

Pimapexole 0.5 Tablet is not meant for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients might be more susceptible to the side effects of Pimapexole 0.5 Tablet. Caution is advised when prescribing this medicine to patients above 70 years of age who might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Interactions of Pimapexole 0.5 Tablet 10

Drug-Drug Interactions

Pimapexole 0.5 Tablet may interact with the following medications, including:

Antipsychotics (such as haloperidol and chlorpromazine): Antipsychotic medications block dopamine receptors, which counteracts the effects of this medicine and may reduce its benefits in Parkinson’s disease and restless legs syndrome.
Antidepressants (like sertraline): Sertraline and other antidepressants may increase drowsiness and dizziness when taken with Pimapexole, leading to a higher risk of sedation and impaired coordination.
Prokinetic agents (like metoclopramide): Metoclopramide blocks dopamine receptors in the brain, which reduces the effectiveness of this medicine and may worsen Parkinson’s symptoms.

Drug-Food Interactions

No drug-to-food interactions have been documented.

Drug-Disease Interactions

Pimapexole 0.5 Tablet can interact with conditions/diseases, including:

Hallucinations or psychosis: Pimapexole 0.5 Tablet activates dopamine receptors, which can exacerbate hallucinations or psychosis, especially in individuals with pre-existing psychiatric conditions. Patients with schizophrenia or other psychotic disorders may experience worsened delusions or confusion. Caution is advised, and the doctor may adjust the dosage or consider alternative treatments.

Daily Dose

Your doctor will prescribe the required daily dose of Pimapexole 0.5 Tablet, based on your individual needs and response to the medicine. Always adhere to this dosage and avoid any changes without consulting your doctor.

Over Dose

Overdosing on this medicine may result in nausea, vomiting, hallucinations, and abnormal body movements. Should these symptoms occur, it's essential to inform your doctor. Do not resort to self-medication or exceed the prescribed dosage.

Missed Dose

If you forget to take your scheduled dose of this medicine, take it as soon as you remember. However, avoid repeating the dose.

The storage instructions for Pimapexole 0.5 Tablet are as follows:

Pimapexole 0.5 Tablet should be stored at room temperature, at 25°C.
Please protect it from light and moisture.
Keep away from children.
Do not use this medicine after the expiry date has passed.

Practise good sleep hygiene. This includes maintaining regular sleep and wake times, keeping the bedroom dark and quiet, avoiding caffeine and alcohol close to bedtime, and engaging in relaxing activities before bed.
Regular mental exercises, such as puzzles, reading, and memory games, can help improve cognitive function in Parkinson's disease patients.

Fact Box

Drug Category	Dopamine receptor agonist
Therapeutic Category	Cognitive function
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Parkinson's disease and restless legs syndrome (RLS) in adults

What is Pimapexole 0.5 Tablet used for?

Pimapexole 0.5 Tablet is used to manage symptoms of Parkinson’s disease and restless legs syndrome (RLS) in adults. It helps improve muscle control, reduce tremors, and ease discomfort in the legs.

How does Pimapexole 0.5 Tablet work?

It acts as a dopamine receptor agonist, mimicking the effects of dopamine, a neurotransmitter that is deficient in Parkinson’s disease. This helps improve movement, coordination, and muscle function.

When should I take Pimapexole 0.5 Tablet?

Take it as prescribed by your doctor. Do not abruptly stop taking this medicine until directed by your doctor.

Can I take Pimapexole 0.5 Tablet with food?

Yes, it can be taken with or without food. Taking it with food may help reduce nausea, a possible side effect.

What are the side effects of Pimapexole 0.5 Tablet?

Common side effects include drowsiness, dizziness, nausea and Constipation. If severe side effects occur, consult your doctor immediately.

Can I take other medicines with Pimapexole 0.5 Tablet?

It may interact with antipsychotics, antidepressants, and prokinetic agents. Always inform your doctor about any other medications you are taking to prevent harmful interactions.

How should I store Pimapexole 0.5 Tablet?

Store it in a cool, dry place, away from moisture and direct sunlight. Keep it out of reach of children.

Last Updated On 05 Mar. 2025 | 4:46PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Tanaji Chowk, Ambedkar Nagar, Kurla West, Kurla, Mumbai, Maharashtra 400070

Country of origin: INDIA

References

Pramipexole: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a697029.html
Pramipexole Uses, Side Effects & Warnings. (n.d.). Drugs.com. https://www.drugs.com/mtm/pramipexole.html
Pramipexole: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00413
Singh, R., & Parmar, M. (2023, April 17). Pramipexole. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK557539/
PubChem. (n.d.). Pramipexole. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Pramipexole

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