Pioride 1 Mg Tablet 10

Pioride 1mg Tablet 10

Alembic Ltd

Strip of 10 Units

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MRP ~~₹205.6~~

₹168.59

₹20.56/Units

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Composition

Prucalopride (1 Mg)

Strength:

2 MG 1 MG

Pioride 1mg Tablet is primarily used to manage chronic idiopathic constipation in adults. It is not a combination product and belongs to the group of medicines known as serotonin-4 (5-HT4) receptor agonists.

By stimulating specific receptors in the gut, this tablet can improve and make bowel movements more regular. This action helps alleviate the discomfort and inconvenience associated with chronic constipation.

Before you start taking this tablet, it's important to consult your doctor for the correct dosage and frequency. Let your doctor know about any other health conditions you have or any other medicines you are currently taking. If you experience any side effects while taking this medicine, inform your doctor immediately. Remember to continue taking this medicine for the full duration prescribed by your doctor to achieve the best results.

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Pioride 1mg Tablet is used for the management of chronic idiopathic constipation in adults.

Directions for Use of Pioride 1mg Tablet 10

To use Pioride 1mg Tablet correctly, follow these instructions:

Swallow the tablet whole with a glass of water.
Do not crush, chew or divide the tablet.
This medicine can be taken with or without food.
Remember, the dosage should be as recommended by your doctor.

Pioride 1mg Tablet is taken orally.

The following common side effects may occur when taking Pioride 1mg Tablet:

Headache
Abdominal pain
Nausea
Diarrhoea
Flatulence
Dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pioride 1mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

To manage common side effects:

Abdominal pain: Taking your tablet with meals may help to lessen any abdominal discomfort.
Dizziness: To avoid feeling dizzy during daily activities, it might be helpful to take your medicine before bedtime.

Pioride 1mg Tablet contains prucalopride (1 mg), which acts on your body in the following ways:

Stimulates 5-HT4 Receptors: Prucalopride stimulates these particular receptors in your gut. This stimulation leads to an increase in gastrointestinal motility, which makes bowel movements happen more easily.
Enhances Peristaltic Reflex: The peristaltic reflex is essentially a series of muscle contractions in your gut that help move food along. Prucalopride enhances this reflex, aiding in regular bowel movements.
Increases Intestinal Secretions: By increasing these secretions, prucalopride helps soften stools and makes them pass more comfortably.
Accelerates Intestinal Transit: With improved transit times, food passes through your system more quickly, leading to more frequent and complete bowel movements.

Pregnancy

If you are pregnant, caution is advised while taking Pioride 1mg Tablet. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it is advisable to consult with your doctor before using this medication.

Alcohol

Combining prucalopride with alcohol can increase the risk of gastrointestinal side effects such as nausea, vomiting, and abdominal pain. It is advisable to limit or avoid alcohol consumption while taking prucalopride to minimise these adverse effects.

Liver

Patients with severe liver impairment need to exercise caution as the exposure to prucalopride may be increased. If you have liver issues, discuss them with your doctor before starting Pioride 1mg Tablet.

Kidney

Pioride 1mg Tablet is contraindicated in patients with renal impairment requiring dialysis. If you have kidney problems, please consult your doctor before using this medicine.

Using Machines & Driving

Prucalopride may cause dizziness. You should exercise caution when driving or operating machinery while on this medication.

Allergy

Pioride 1mg Tablet should not be taken if you have any known hypersensitivity to prucalopride or any of the excipients included in the tablet.

Children

It's advised to consult your doctor before giving this medicine to a child.

Older Patients

Elderly patients may be more sensitive to the effects of prucalopride. Therefore, they should take Pioride 1mg Tablet under medical supervision as they might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Pioride 1mg Tablet interacts with the following medicines:

Serotonin-4 (5-HT4) Receptor Agonists: Co-administration of Pioride 1mg Tablet with other 5-HT4 agonists, such as cisapride or mosapride, should be avoided due to the potential for additive effects.
CYP3A4 Inhibitors (e.g., ketoconazole, itraconazole, erythromycin): These medications can increase the plasma concentration of prucalopride by inhibiting its metabolism.
QT-Prolonging Medications: Combining prucalopride with medications like amiodarone, sotalol, and quinidine that prolong the QT interval may increase the risk of arrhythmias.

Drug-Food Interactions

There are no known food and beverage interactions with Pioride 1mg Tablet. Therefore, it can be taken with or without food.

Drug-Disease Interactions

Pioride 1mg Tablet interacts with the following diseases:

Renal Impairment: Pioride 1mg Tablet is contraindicated in patients requiring dialysis due to renal impairment.
Intestinal Disorders: This medicine is not suitable for patients suffering from intestinal perforation or obstruction and severe inflammatory conditions of the intestinal tract, such as Crohn's disease, ulcerative colitis, and toxic megacolon/megarectum.
Heart Conditions: Patients with a history of arrhythmias or ischemic heart disease need to exercise caution while using this medicine.

Daily Dose

Pioride 1mg Tablet should be taken as your doctor prescribes. The dosage may differ based on the severity of your condition and how you respond to the medicine. Remember, it's crucial to stick to the prescribed dosage and consult your doctor before making any changes.

Over Dose

If you accidentally take more Pioride 1mg Tablet than prescribed, you might experience symptoms like frequent bowel movements, abdominal cramps and diarrhoea. It's important to inform your doctor if these symptoms persist or worsen.

Missed Dose

In case you forget a dose of Pioride 1mg Tablet, take it as soon as you remember it. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase the dose without consulting your doctor.

Store Pioride 1mg Tablet in a cool and dry place, ideally at room temperature not exceeding 30°C.
Keep it shielded from direct light and moisture.
Always remember to keep this medicine out of the reach of children.
Use Pioride 1mg Tablet before its expiry date.

Since constipation can be improved with dietary changes, including more fibre-rich foods, such as fruits, vegetables, and whole grains, in your diet. This can help stimulate your bowel movements.
Regular physical activity can also strengthen your digestive system. Try including at least 30 minutes of exercise in your daily routine to improve the symptoms managed by Pioride 1mg Tablet.

Fact Box

Drug Category	Serotonin-4 Receptor Agonist
Therapeutic Category	Gastroprokinetic Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic Idiopathic Constipation

What is Pioride 1mg Tablet used for?

This medication is used to manage chronic idiopathic constipation in adults by enhancing bowel movements.

How does Pioride 1mg Tablet work?

It works by stimulating certain receptors in the gut, which increases its movement and promotes regular bowel movements.

Can I take Pioride 1mg Tablet with food?

Yes, you can take this medicine with or without food. Always swallow the tablet whole with a glass of water.

What should I do if I miss a dose?

If you miss a dose, skip the missed one and continue with your regular schedule. Avoid taking two doses at once.

Can I drive after taking Pioride 1mg Tablet?

Be cautious as this medicine may cause dizziness. Consult your doctor if you need to drive or operate machinery.

Can I take Pioride 1mg Tablet during pregnancy?

Always consult your doctor before taking this medication during pregnancy as it may not be safe.

Are there any known side effects of Pioride 1mg Tablet?

Common side effects include headache, abdominal pain, nausea, diarrhoea, flatulence and dizziness. These are usually mild and temporary.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

7c, Bhagoji Keer Marg, Bethany Co-Operative Housing Society, Mahim West, Mahim, Mumbai, Maharashtra 400016

Country of origin: INDIA

References

Shire. (2018). Highlights of prescribing information for motegrity [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210166s000lbl.pdf
Prucalopride: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a619011.html
DailyMed - MOTEGRITY- prucalopride tablet, film coated. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=bca1e4c6-4b2b-4876-8ab3-654629c4ff1b
Prucalopride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06480

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