Piosys 15 Tablet 30

Systopic Laboratories Private Limited

Strip of 30 Units

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MRP ~~₹54~~

₹43.2

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Composition

Pioglitazone (15 Mg)

Strength:

30 MG 15 MG

Piosys-15 Tablet is primarily employed to manage type 2 diabetes in adults. This medicine is included in the thiazolidinedione group of medicines.

This medicine helps to restore the body's sensitivity to insulin, thereby assisting in lowering your blood glucose levels. Proper control of diabetes can prevent or delay complications such as kidney damage, blindness, and nerve problems, and even reduce the risk of heart attack and stroke.

Before beginning this medicine, it's crucial to consult your doctor and inform them about any pre-existing conditions or ongoing medications. If you notice any side effects while on this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Piosys-15 Tablet is used for the following:

Managing type 2 diabetes mellitus in adults
Improving glycemic control in type 2 diabetes patients
Restoring the body's sensitivity to insulin
Assisting in the prevention of kidney damage due to diabetes
Helping prevent nerve problems associated with diabetes
Aiding in reducing the risk of limb amputations from diabetic complications
Helping prevent sexual dysfunction caused by diabetes
Reducing the risk of heart attack and stroke in diabetic patients

Directions for Use of Piosys 15 Tablet 30

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Do not take more than the advised dose without consulting your doctor.
Remember, it's important not to stop taking this medicine without speaking to your doctor first.

Piosys-15 Tablet is taken orally.

Piosys-15 Tablet may have the following side effects:

Upper respiratory tract infection
Headache
Sinusitis
Myalgia: This is a medical term for muscle pain.
Tooth disorder
Aggravated diabetes mellitus: This refers to the worsening of your existing type 2 diabetes condition.
Pharyngitis: This means inflammation of the pharynx, leading to a sore throat.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Piosys-15 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Upper respiratory tract infection: Make sure to rest and hydrate well while taking Piosys-15 Tablet.
Headache: Consider taking Piosys-15 Tablet after meals to reduce the likelihood of headaches.

Piosys-15 Tablet contains pioglitazone (15 mg) which works on your body through the following mechanisms:

Agonist of PPAR-γ: Pioglitazone is an agonist of peroxisome proliferator-activated receptor-gamma (PPAR-γ). This means it activates these receptors, which are involved in controlling genes related to glucose and fat metabolism.
Increases Insulin Sensitivity: By activating PPAR-γ nuclear receptors, pioglitazone increases the sensitivity of insulin-dependent tissues like your adipose tissue (fat), skeletal muscles, and liver. This results in more efficient use of glucose and a decrease in glucose production by your liver.
Blood Lipids Management: Besides managing your blood sugar levels, pioglitazone also manages your blood lipids. It reduces triglyceride levels (a type of fat) in your blood and increases high-density lipoprotein (HDL) cholesterol, often referred to as the 'good' cholesterol.

Pregnancy

Caution is advised while taking Piosys-15 Tablet if you are pregnant. It would be best to consult your doctor before starting this medicine.

Breastfeeding

Piosys-15 Tablet should be used with caution by breastfeeding women. It's important to discuss this with your doctor before taking this medication.

Alcohol

Drinking alcohol while using Piosys-15 Tablet may affect how the medicine works. Discuss with your doctor about any concerns related to alcohol consumption.

Liver

If you have liver problems, caution is advised when taking Piosys-15 Tablet. Ensure you discuss any liver-related health issues with your doctor before starting this medication.

Kidney

For those having kidney health concerns, it is recommended to consult your doctor before using Piosys-15 Tablet. Your doctor will guide you based on your health status.

Using Machines & Driving

Piosys-15 Tablet may not directly affect your ability to drive or operate machinery, but it's always good to discuss any doubts with your doctor.

Allergy

If you have known allergies, particularly a hypersensitivity to pioglitazone, Piosys-15 Tablet should not be taken. Always inform your doctor about any allergies beforehand.

Children

Caution is advised while giving Piosys-15 Tablet to children under 18 years of age. Always consult your doctor before administering this medicine to a child.

Older Patients

Older patients should take Piosys-15 Tablet under medical supervision as they may be more susceptible to their effects. Caution is advised for patients above 70 years of age as they might have liver and kidney issues, and might be on other medications. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Piosys-15 Tablet interacts with the following medicines:

CYP2C8 Inhibitors: Medicines such as gemfibrozil can interact with Piosys-15 Tablet, potentially affecting the way it works in your body.
CYP2C8 Inducers: Medicines like rifampin can increase the breakdown of pioglitazone in your body, reducing its effectiveness.
Insulin or Insulin Secretagogues: Combining Piosys-15 Tablet with insulin or insulin secretagogues may increase the risk of low blood sugar levels (hypoglycaemia).
Oral Contraceptives: Piosys-15 Tablet may decrease the effectiveness of oral contraceptives, which could lead to unintended pregnancy.

Drug-Food Interactions

There are no specific food items known to interact with Piosys-15 Tablet.

Drug-Disease Interactions

Piosys-15 Tablet interacts with the following diseases:

Type 1 Diabetes and Diabetic Ketoacidosis: Piosys-15 Tablet is not suitable for these conditions as it works by increasing insulin sensitivity, which is not helpful in type 1 diabetes or diabetic ketoacidosis.
Heart Failure (NYHA Class III or IV): Patients with these conditions should not take Piosys-15 Tablet as it may worsen their heart function.
Liver Disease: People suffering from liver disease should use Piosys-15 Tablet with caution as it can further impair liver function.

Daily Dose

Your doctor will prescribe the appropriate daily dose of Piosys-15 Tablet for you. This dosage may vary depending on your specific condition and how well you respond to treatment. Stick to the prescribed dosage and don't exceed it without having a chat with your doctor. For further details regarding dosage, refer to the package insert.

Over Dose

If you accidentally take more Piosys-15 Tablets than prescribed, you may experience symptoms like headache, sinusitis, or muscle pain. If these symptoms persist or worsen, it's important to inform your doctor. Remember, overdosing is not a solution and can lead to unnecessary complications.

Missed Dose

In case you miss a dose of Piosys-15 Tablet, take it as soon as you remember. If it's almost time for the next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Store Piosys-15 Tablet at room temperature, ideally below 30°C.
Keep the medicine away from light and moisture.
Make sure to keep this medication out of sight and reach of children.
Always use the Piosys-15 Tablet before the expiry date mentioned on the packaging.

Consider adopting a balanced diet rich in fibre and low in simple sugars; this aids in managing type 2 diabetes, which Piosys-15 Tablet helps manage.
Regular physical activity, such as mild exercise or daily walks, can also assist in controlling blood glucose levels.

Fact Box

Drug Category	PPAR-γ Agonist
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What is the Piosys-15 Tablet used for?

The Piosys-15 Tablet is used to manage type 2 diabetes, helping to lower blood glucose levels and increasing the body's sensitivity to insulin.

How does the Piosys-15 Tablet work?

Piosys-15 Tablet works by activating certain receptors that enhance the function of insulin-responsive genes, leading to improved glucose utilisation and decreased glucose production.

Can I take Piosys-15 Tablet with other antidiabetic medications?

Yes, Piosys-15 Tablet can be taken with metformin, sulfonylureas, or insulin under medical supervision. Always consult your doctor before starting any medication.

How long does it take for Piosys-15 Tablet to start working?

The full effect of Piosys-15 Tablet may take 8-12 weeks, but some improvement may be noticed within 2 weeks of regular usage as directed by your doctor.

What should I do if I miss a dose of Piosys-15 Tablet?

If you miss a dose of Piosys-15 Tablet, take it as soon as you remember unless it's nearly time for your next dose. Never double up doses.

Can Piosys-15 Tablet cause low blood sugar (hypoglycemia)?

Alone, Piosys-15 Tablet rarely causes hypoglycemia. However, combining it with insulin or insulin secretagogues might increase the risk. Consult your doctor for guidance.

Is it safe to take Piosys-15 Tablet during pregnancy?

It's crucial to discuss this with your doctor as the use of Piosys-15 Tablet during pregnancy should only occur if the potential benefit justifies the potential risk.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

101 PRAGATI CHAMBERS RANJIT NAGAR COMMERCIAL , NEW DELHI, Delhi, India - 110008

Country of origin: INDIA

References

NHS UK. (n.d.). Pioglitazone. NHS. Retrieved 1 April 2024, from https://www.nhs.uk/medicines/pioglitazone/about-pioglitazone/
U.S. Food and Drug Administration. (2009). Medication Guide: Pioglitazone. FDA. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021842s009MedGuide.pdf
Pioglitazone. (n.d.). Retrieved 11 October 2024, from
https://go.drugbank.com/drugs/DB01132
Singh, G., Can, A. S., & Correa, R. (2024). Pioglitazone. In StatPearls. StatPearls Publishing. Retrieved 11 October 2024, from
https://www.ncbi.nlm.nih.gov/books/NBK544287/
Pioglitazone: Medlineplus drug information. (n.d.). Retrieved 11 October 2024, from
https://medlineplus.gov/druginfo/meds/a699016.html

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