Pirfenex 801mg Tablet 10

Cipla Ltd.

Strip of 10 Units

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MRP ~~₹780.45~~

₹624.36

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Composition

Pirfenidone (801 Mg)

Pirfenex 801mg Tablet is primarily prescribed for the treatment of idiopathic pulmonary fibrosis (IPF) in adults. It belongs to a class of anti-fibrotic and anti-inflammatory medicines.

This medication helps slow the progression of IPF, a condition where scar tissue develops in the lungs, causing difficulty in breathing. While it aids in managing the condition and improving quality of life, it is not a cure for the disease.

Before starting this tablet, consult your doctor to determine the correct dosage and frequency. Inform your doctor about any existing health conditions or medications you are taking to avoid potential interactions. If you experience any side effects, report them to your doctor promptly.

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Pirfenex 801mg Tablet is used in the following conditions:

Management of mild to moderate idiopathic pulmonary fibrosis in adults
Slowing down the progression of idiopathic pulmonary fibrosis

Directions for Use of Pirfenex 801mg Tablet 10

Take Pirfenex 801mg Tablet in the following way:

Take it as prescribed by your doctor.
Swallow the tablet whole with a glass of water.
It is advisable to take it at the same time each day to maintain the proper level of medication in the body.
Only alter the dosage or discontinue the medication after consulting your doctor.

Pirfenex 801mg Tablet is taken orally.

Side Effects of Pirfenex 801mg Tablet 10

Some common side effects of Pirfenex 801mg Tablet include:

Nausea
Rash
Abdominal pain
Upper respiratory tract infection
Diarrhoea
Fatigue
Headache

Managing the Side Effects:

Most of the side effects resolve on discontinuation of the tablet and are temporary and, in the majority of cases, do not require medical attention. If you experience severe or persistent side effects from this tablet, consult your doctor.

Here are a few tips for managing common side effects:

Diarrhoea: Stay hydrated and avoid fatty or spicy foods.
Nausea: Take the medication with plenty of water.

Pirfenex 801mg Tablet contains the following component:

Pirfenidone (801 mg): Pirfenidone works by inhibiting the production of transforming growth factor-beta (TGF-β), a protein that plays a key role in the formation of scar tissue in the lungs. By blocking TGF-β, it helps reduce fibrosis (scar tissue buildup) and inflammation, thereby preserving lung function in patients with idiopathic pulmonary fibrosis (IPF).

Pregnancy

Pirfenex 801mg Tablet should be used with caution during pregnancy, as its safety is not well established. Consult your doctor before starting this medication.

Breastfeeding

The potential risk to infants cannot be ruled out. If you are breastfeeding, discuss the benefits and risks of taking this medicine with your doctor.

Alcohol

There is no known interaction between Pirfenex 801mg Tablet and alcohol. However, consult your doctor for personalised advice.

Liver

Use Pirfenex 801mg Tablet cautiously if you have mild to moderate liver impairment. It is not recommended for severe liver conditions. Regular liver function monitoring may be required during treatment.

Kidney

Pirfenex 801mg Tablet does not require dose adjustments for mild to moderate kidney impairment. Its safety in severe kidney impairment or end-stage renal disease requiring dialysis has not been studied. Consult your doctor before use.

Using Machines & Driving

If you experience dizziness or similar side effects, avoid driving or operating machinery. Discuss these symptoms with your doctor.

Allergy

Do not use Pirfenex 801mg Tablet if you are allergic to pirfenidone or any of its components. Inform your doctor about any known allergies before starting this medication.

Children

The safety and efficacy of Pirfenex 801mg Tablet in children have not been established. Consult your doctor before giving this medicine to a child.

Older Patients

Older adults generally do not require dose adjustments based on age. However, medical supervision is recommended due to the potential for age-related liver or kidney issues.

Interactions of Pirfenex 801mg Tablet 10

Drug-Drug Interactions

Pirfenex 801mg Tablet can interact with medications, including:

Antidepressants: Medicines like fluvoxamine can elevate pirfenidone levels, increasing the risk of side effects such as nausea and dizziness.
Antibiotics: Medications like rifampin can reduce pirfenidone levels, potentially lowering its effectiveness.
Oral Corticosteroids: Using methylprednisolone alongside this medication may heighten the risk of gastrointestinal side effects like nausea or indigestion.

Drug-Food Interactions

Pirfenex 801mg Tablet is not known to interact with any foods.

Drug-Disease Interactions

Pirfenex 801mg Tablet can interact with diseases, including:

Liver Disease: Patients with liver disease should use Pirfenex 801mg Tablet cautiously, as it may exacerbate liver dysfunction. Regular liver function monitoring is advised.
Kidney Disease: This medicine is safe for mild to moderate renal impairment but has not been studied in severe kidney disease or patients requiring dialysis. Consult your doctor for guidance.
Sun Sensitivity: Pirfenidone can cause photosensitivity reactions. Individuals prone to sun sensitivity should take extra care to limit sun exposure and use protective measures while on this medication.

Daily Dose

Take the daily dose of this medicine as prescribed by your doctor. The exact dosage may vary based on individual factors such as the severity of the condition and the response to treatment. To ensure safe and effective use, it is essential to adhere to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

In the event of accidentally consuming an excessive amount of this medicine, immediate medical attention should be sought from a doctor or nearby hospital. You might feel a bit nauseous or have some stomach discomfort. It is crucial to receive appropriate medical care to manage the situation effectively.

Missed Dose

If a dose of this medicine is missed, it is advised to take it as soon as you remember. However, avoid repeating the dose.

Store this tablet at room temperature 30ºC.
Protect it from light and moisture.
Keep it away from children.
Do not use this medicine after the expiry date has passed.

If you are managing idiopathic pulmonary fibrosis (IPF) with Pirfenex 801mg Tablet, it is essential to quit smoking. Smoking can aggravate your lung condition and may reduce the effectiveness of the medication.
This tablet may increase your sensitivity to sunlight. To prevent photosensitivity reactions, wear protective clothing and apply sunscreen when spending time outdoors.

Fact Box

Drug Category	Anti-fibrotic
Therapeutic Category	Anti-inflammatory
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Idiopathic Pulmonary Fibrosis

What is Pirfenex 801mg Tablet used for?

This tablet is used to manage idiopathic pulmonary fibrosis (IPF), a condition that causes scarring of the lungs, leading to breathing difficulties.

How does Pirfenex 801mg Tablet work?

This tablet blocks the production of proteins involved in lung scarring and inflammation, reducing fibrosis and preserving lung function.

Are there any precautions before taking Pirfenex 801mg Tablet?

Inform your doctor about any pre-existing conditions, ongoing medications, or allergies. Avoid sun exposure and smoking while taking this medicine.

How should I take Pirfenex 801mg Tablet?

Take this medicine with food as directed by your doctor. Follow the prescribed dosage and schedule strictly.

Can I stop taking Pirfenex 801mg Tablet suddenly?

No, do not stop taking this tablet without consulting your doctor, as this may worsen your condition.

What are the common side effects of Pirfenex 801mg Tablet?

Common side effects include nausea, dizziness, loss of appetite, diarrhoea, and sensitivity to sunlight. Consult your doctor if these persist or worsen.

Last Updated On 18 Jan. 2025 | 3:25PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

InterMune. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/022535s000lbl.pdf
ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (n.d.). https://www.ema.europa.eu/en/documents/product-information/esbriet-epar-product-information_en.pdf
Sandoz Canada Inc. (2020). SANDOZ PIRFENIDONE TABLETS. In SANDOZ PIRFENIDONE TABLETS (pp. 1–42) [Product monograph]. https://pdf.hres.ca/dpd_pm/00060877.PDF
Pirfenidone: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB04951
PubChem. (n.d.). Pirfenidone. PubChem. https://pubchem.ncbi.nlm.nih.gov/compound/Pirfenidone

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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