Pradaxa 150 Mg Capsule 10

Pradaxa 150mg Capsule 10

Boehringer Ingelheim

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Composition

Dabigatran Etexilate (150 Mg)

Strength:

75 MG 150 MG 110 MG

Pradaxa 150mg Capsule is utilised to lower the risk of stroke and blood clots in individuals with certain heart conditions. This medication falls under the category of direct thrombin inhibitors, a group of medicines that prevent blood clot formation.

This capsule is also used to manage and prevent systemic embolism in adults with non-valvular atrial fibrillation, a condition characterised by irregular heartbeat. Additionally, it plays a crucial role in treating and preventing deep vein thrombosis (clots in the deep veins of the legs) and pulmonary embolism (clots in the lungs).

The medicine should be taken orally as directed by your doctor. It's important to inform your doctor about any pre-existing conditions or ongoing medicines before starting this capsule. If you notice any adverse effects while on this medicine, notify your doctor promptly. Ensure you continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Pradaxa 150mg Capsule is used to manage:

The risk of stroke in adults with certain heart conditions
The prevention of systemic embolism in adults with non-valvular atrial fibrillation, a condition characterised by irregular heartbeat
Deep vein thrombosis, which involves blood clots forming in the deep veins of your legs
Pulmonary embolism, a condition where blood clots block the arteries in your lungs

Directions for Use of Pradaxa 150mg Capsule 10

Swallow the capsule whole with a full glass of water.
This medicine can be taken with or without food.
Ensure you don't chew or break the capsule.
Remember not to stop taking this medicine without consulting your doctor first.

Pradaxa 150mg Capsule is taken orally.

Side Effects of Pradaxa 150mg Capsule 10

Like all medicines, Pradaxa 150mg Capsule can cause certain side effects. Here are the most common ones:

Bruising easily
Nosebleeds
Prolonged bleeding from cuts
Heavy menstrual bleeding
Blood in urine or stools
Indigestion
Stomach pain
Nausea
Diarrhoea

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pradaxa 150mg Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some tips to manage common side effects:

Indigestion: Try taking Pradaxa 150mg Capsule with food to reduce this effect.
Diarrhoea: Consider drinking plenty of fluids to replace lost water and electrolytes.

Pradaxa 150mg Capsule contains Dabigatran Etexilate (150 mg), which works on your body in the following ways:

Inhibiting Thrombin: Dabigatran etexilate works by directly blocking an enzyme called thrombin in your body. Thrombin plays a significant role as it aids in transforming fibrinogen into fibrin during the clotting process.
Preventing Clot Formation: By inhibiting thrombin, dabigatran etexilate stops fibrinogen from converting into fibrin, thereby preventing blood clots. The anticoagulant effect of this mechanism significantly reduces the risk of stroke and other clot-related complications in susceptible patients.

Pregnancy

Caution is advised while taking Pradaxa 150mg Capsule if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you're breastfeeding, consult your doctor before starting Pradaxa 150mg Capsule. Your doctor will help decide what's best for you and your baby.

Alcohol

The interaction of Pradaxa 150mg Capsule with alcohol is unknown. Hence, please consult your doctor for advice.

Liver

Caution is advised while taking Pradaxa 150mg Capsule if you have liver health problems. Discuss your liver health with your doctor before starting this medicine.

Kidney

In case of kidney health issues, caution is advised before using Pradaxa 150mg Capsule. Your doctor will guide you based on your health status.

Using Machines & Driving

Pradaxa 150mg Capsule does not usually affect your ability to drive or operate machinery. If you feel dizzy or unwell after taking this medicine, avoid these activities and seek medical advice.

Allergy

If you have known allergies to dabigatran etexilate or any other ingredients in Pradaxa 150mg Capsule, do not take this medicine. Always inform your doctor about any allergies before starting a new medication

Children

Pradaxa 150mg Capsule is not recommended for use in children below 18 years of age. Always consult a doctor before giving any medicine to a child.

Older Patients

Older patients should take Pradaxa 150mg Capsule under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.

Interactions of Pradaxa 150mg Capsule 10

Drug-Drug Interactions

Pradaxa 150mg Capsule interacts with the following medicines:

Antibiotics: Medicines like rifampin can lessen the effectiveness of Pradaxa 150mg Capsule by reducing dabigatran levels.
Antifungals: Medicines such as ketoconazole can heighten the risk of bleeding by increasing dabigatran levels.
Anticoagulants: Other blood-thinning medications like warfarin can increase the risk of bleeding when taken with Pradaxa 150mg Capsule.
NSAIDs: Medications used for pain relief, such as naproxen, can increase bleeding risks when used along with Pradaxa 150mg Capsule.

Drug-Food Interactions

There are no specific known food interactions with Pradaxa 150mg Capsule.

Drug-Disease Interactions

Pradaxa 150mg Capsule interacts with following diseases:the

Kidney Disease: Patients with impaired kidney function may need dosage adjustments or should avoid Pradaxa 150mg Capsule.
Active Pathological Bleeding: Patients suffering from active bleeding should not use Pradaxa 150mg Capsule due to increased risk of further bleeding.
Hypersensitivity: Those who have had a severe allergic reaction to dabigatran should not use Pradaxa 150mg Capsule.
Prosthetic Heart Valves: Patients with mechanical prosthetic heart valves should avoid this medication.

Daily Dose

Follow your doctor's advice for the daily dose of Pradaxa 150mg Capsule. Individual factors like your health condition and how you respond to the medicine can influence the dosage. Always adhere to your doctor's instructions; do not alter the dosage without consulting them.

Over Dose

Excessive intake of Pradaxa 150mg Capsule may lead to an increased risk of bleeding complications. If you accidentally take more than your prescribed dose, please consult your doctor right away.

Missed Dose

If you forget to take a dose of Pradaxa 150mg Capsule, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Do not increase your dosage without speaking to your doctor.

Keep Pradaxa 150mg Capsule ideally below 30°C.
Keep away from excessive heat and moisture.
Always ensure it's out of reach of children.
Check the expiry date before use; avoid using expired medicine.

Drinking plenty of water helps maintain blood flow and may prevent blood clots, which is beneficial for individuals taking Pradaxa 150mg Capsule.
Regular, low-impact activities like walking or swimming can help improve circulation and reduce the risk of developing blood clots. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Direct Thrombin Inhibitor
Therapeutic Category	Anticoagulant
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Non-valvular Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism

What is Pradaxa 150mg Capsule used for?

Pradaxa 150mg Capsule is mainly used to prevent strokes and blood clots in adults with an irregular heartbeat called non-valvular atrial fibrillation.

How does Pradaxa 150mg Capsule work?

The active ingredient in Pradaxa 150mg Capsule, dabigatran etexilate, inhibits an enzyme called thrombin, preventing the formation of blood clots and reducing the risk of stroke.

How should I take Pradaxa 150mg Capsule?

You should swallow the capsule whole with a full glass of water, either with or without food, as per your doctor's instructions.

What common side effects can Pradaxa 150mg Capsule cause?

Common side effects include easy bruising, nosebleeds, prolonged bleeding from cuts, heavy periods, blood in urine or stools, indigestion, stomach pain, nausea and diarrhoea.

Who should not take Pradaxa 150mg Capsule?

Avoid taking Pradaxa 150mg Capsule if you have active bleeding, a history of severe allergic reaction to dabigatran, or a mechanical prosthetic heart valve.

Can other medicines interfere with Pradaxa 150mg Capsule?

Yes. Certain medicines can affect how well Pradaxa 150mg Capsule works or increase your risk of bleeding. Always inform your doctor about all the medicines you're currently taking.

What if I miss a dose of Pradaxa 150mg Capsule?

If you miss a dose of Pradaxa 150mg Capsule, take it as soon as possible on the same day. Never take two doses at once to make up for a missed one.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

1102, Hallmark Business Plaza, 11th Floor, Gurunanak Hospital Road, near Gurunanak Hospital, Bandra East, Mumbai, Maharashtra 400051

Country of origin: GERMANY

References

Boehringer Ingelheim Pharmaceuticals, Inc. (2010). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. In Pradaxa 150mg Capsule (pp. 1–3). https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/022512s007lbl.pdf
DailyMed - Pradaxa 150mg Capsule- dabigatran etexilate mesylate capsule. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5db7f199-8752-4d24-85f7-e34ca8f4d02e
Boehringer Ingelheim. (n.d.). SUMMARY OF PRODUCT CHARACTERISTICS. https://www.ema.europa.eu/en/documents/product-information/Pradaxa 150mg Capsule-epar-product-information_en.pdf
Ashrafi, F., Rezaie, N., & Mousavi, S. (2017). New indications for dabigatran: A suggestion from a drug use evaluation study. Journal of Research in Pharmacy Practice, 6(4), 211. https://doi.org/10.4103/jrpp.jrpp_17_54
Dabigatran etexilate: Uses, Interactions, Mechanism of Action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06695

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