Pruease 2 Mg Tablet 10

Pruease 2mg Tablet 10

Sun Pharma Laboratories Ltd.

Strip of 10 Units

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MRP ~~₹359~~

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Composition

Prucalopride (2 Mg)

Strength:

2 MG 1 MG

Pruease 2mg Tablet is a key medicine used to manage chronic constipation. This medicine belongs to the group of medications known as selective serotonin (5-HT4) receptor agonists.

This medicine is useful in cases where other conventional laxatives have not provided adequate relief. By stimulating bowel movements, the tablet improves the discomfort associated with long-term constipation.

It's crucial to take this medicine as directed by your doctor. Before starting the tablet, ensure your doctor knows of any pre-existing conditions or ongoing medications you're taking. If you experience any side effects while on this medicine, inform your doctor immediately. For optimal results, it's important to continue taking the medicine for the entire duration prescribed by your doctor.

Pruease 2mg Tablet is used to manage chronic constipation in adults.

Directions for Use of Pruease 2mg Tablet 10

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Take the medicine in the dosage and frequency prescribed by your doctor.
Always consult your doctor for further guidance.

Pruease 2mg Tablet is taken orally.

Pruease 2mg Tablet may have the following common side effects:

Nausea and vomiting
Diarrhoea
Abdominal pain
Indigestion
Headache
Dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the medicine. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can also effectively manage common side effects like nausea, vomiting, diarrhoea, and abdominal pain at home by taking the medicine with food or after meals.

Pruease 2mg Tablet contains prucalopride (2mg) as the active ingredient. It works in your body in the following manner:

Prucalopride is a selective serotonin (5-HT4) receptor agonist that works by stimulating the release of acetylcholine, a natural chemical in the body that increases the motility (movement) of the intestines.
The increased intestinal motility helps food move more efficiently through the digestive tract. This action aids in regular bowel movements and effectively manages chronic constipation.

Pregnancy

It is better to avoid Pruease 2mg Tablet during pregnancy unless the benefits outweigh the risks. It is best to consult your doctor before taking this medicine.

Breastfeeding

Caution is advised for breastfeeding women, as the medicine may pass into breast milk and harm the nursing infant. Always consult your doctor before taking this medicine.

Alcohol

Avoid consuming alcohol while on this medication as it may increase the risk of side effects or complications. Always consult your doctor regarding alcohol intake.

Liver

Patients with severe liver disease should use the medicine with caution. Always consult your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, exercise caution when taking this medicine. Your doctor may recommend dosage adjustments if necessary.

Using Machines & Driving

Pruease 2mg Tablet might cause dizziness in some individuals. Avoid driving or operating machinery until you know how the medicine affects you.

Allergy

The medicine is contraindicated if you're allergic to prucalopride or any other component of the tablet. Always discuss your allergies with your doctor.

Children

The medicine is not intended for use in children. Always consult your child's doctor for other safer alternatives.

Older Patients

Older patients, especially those with liver or kidney issues, might be more susceptible to the medicine's side effects. Always consult your doctor for guidance based on your health status.

Drug-Drug Interactions

Pruease 2mg Tablet may interact with the following medications:

CYP3A inhibitors: Medicines like ketoconazole when taken along with Pruease 2mg Tablet may increase the level of prucalopride in your body, causing adverse effects.
Anti-ulcer medicines: Concomitant use of medications like omeprazole or pantoprazole may increase the risk of side effects.
Antidepressants: Medicines like fluoxetine or sertraline could reduce the effectiveness of Pruease 2mg Tablet.

Drug-Food Interactions

Pruease 2mg Tablet may interact with certain foods, such as:

Grapefruit juice: Grapefruit juice should be avoided while taking this medication as it could potentially increase the risk of side effects.

Drug-Disease Interactions

Pruease 2mg Tablet may interact with the following diseases:

Inflammatory bowel diseases: Individuals suffering from conditions like Crohn's disease or ulcerative colitis are contraindicated from using this medication due to potential complications.
Ileus and bowel obstruction: The medicine is contraindicated in patients with ileus and bowel obstruction as it may worsen their condition.
Megacolon/megarectum: Pruease 2mg Tablet is also contraindicated in patients with a megacolon (abnormal colon dilation) or megarectum.
Liver or kidney disease: Patients with severe liver or kidney disease should use the medicine cautiously as it could exacerbate their condition.

Daily Dose

You should take the daily dose of Pruease 2mg Tablet as prescribed by your doctor. The dosage may vary based on factors like how severe your condition is and how you respond to the medication.

Over Dose

In case you accidentally take more than the prescribed dose of the medicine, you might experience overdose symptoms like headache, nausea, abdominal pain, or diarrhoea. If these symptoms persist or worsen, inform your doctor immediately.

Missed Dose

If you forget to take the medicine at the usual time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and follow your regular dosage schedule. Don't increase your dosage without consulting your doctor.

Ensure Pruease 2mg Tablet is stored at room temperature, ideally below 30°C.
Keep this medicine away from direct light, heat, and moisture.
Keep the medicine out of reach of children.
Always check the expiry date and use the medicine before it expires.

Staying well-hydrated can help your system cope better. It will aid digestion and bowel movement, managing your constipation more effectively.
Consuming fibre-rich foods like fruits, vegetables, and whole grains can promote regular bowel movements.

Fact Box

Drug Category	5-HT4 Receptor Agonist
Therapeutic Category	Laxative
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic constipation

What is Pruease 2mg Tablet used for?

Pruease 2mg Tablet is primarily used to manage chronic constipation in adults, especially when laxatives have not provided adequate relief.

How does Pruease 2mg Tablet work?

The active ingredient, prucalopride, stimulates the release of acetylcholine, a neurotransmitter that increases bowel movement, effectively managing chronic constipation.

How should I take Pruease 2mg Tablet?

You should take Pruease 2mg Tablet orally in the dosage and frequency prescribed by your doctor. Swallow the whole tablet with water, without chewing or crushing it.

What are the common side effects of Pruease 2mg Tablet?

The possible side effects of the medicine include headache, nausea, diarrhoea, abdominal pain, dizziness, and indigestion. If these symptoms persist, consult your doctor.

Can I take Pruease 2mg Tablet during pregnancy or while breastfeeding?

It is better to avoid Pruease 2mg Tablet during pregnancy and breastfeeding due to potential risks. Always consult your doctor before taking any medication.

Are there any precautions while taking Pruease 2mg Tablet?

Use caution if you have severe kidney or liver disease. It should be avoided by individuals with certain bowel conditions like Crohn's disease or known allergies to prucalopride.

Can other medications interact with Pruease 2mg Tablet?

Yes, some medications like antidepressants and anti-ulcer medicines may interact with Pruease 2mg Tablet affecting their effectiveness or causing side effects. Inform your doctor about all medications you are currently taking.

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

Shire. (2018). Highlights of prescribing information for motegrity [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/210166s000lbl.pdf
Prucalopride: safety, efficacy and potential applications. (2012, January). ncbi.nlm.nih.gov. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263983/
Prucalopride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06480#
Prucalopride: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a619011.html
Prucalopride. (n.d.). sciencedirect.com. https://www.sciencedirect.com/topics/medicine-and-dentistry/prucalopride

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