Pruvict 1 Tablet 10

Torrent Pharmaceuticals Ltd.

Strip of 10 Units

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MRP ~~₹237~~

₹189.6

₹23.7/Units

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Composition

Prucalopride (1 Mg)

Strength:

2 MG 1 MG

Pruvict 1 Tablet is primarily used to manage chronic constipation in adults. This medicine is part of the selective serotonin type 4 (5-HT4) receptor agonists class of medications.

Besides chronic constipation, it provides relief from the pain and discomfort associated with this condition, especially when typical laxatives don't offer sufficient relief. It's known for stimulating bowel movements and enhancing intestinal motility.

It's crucial to take this medicine as directed by your doctor. Before starting on this medicine, inform your doctor about any pre-existing conditions or ongoing medicines you're using. If you experience any side effects while taking this medicine, notify your doctor immediately. For optimal results, continue taking the medicine for the entire duration prescribed by your doctor.

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Pruvict 1 Tablet is used for the following:

Addressing chronic constipation in adults.
Stimulating bowel movements when laxatives fail to work.
Increasing the motility of the intestines to alleviate long-term constipation.
Improving quality of life by relieving constipation-related discomfort.
Facilitating the gastric emptying of solids and liquids to promote regular bowel movements.

Directions for Use of Pruvict 1 Tablet 10

Here's how you should take Pruvict 1 Tablet:

Thoroughly follow the dosage and timing guidelines provided by your doctor for taking this medicine.
Do not change or exceed the prescribed dose without consulting your doctor.
Avoid discontinuing this medication without your doctor's advice. Always consult your doctor before stopping.
Adhere to the diet plan recommended by your doctor.

Pruvict 1 Tablet is taken orally.

Pruvict 1 Tablet might lead to a few common side effects, including:

Headache
Nausea
Diarrhoea
Abdominal pain
Decreased appetite
Dizziness
Indigestion

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Pruvict 1 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Below are some suggestions to manage common side effects:

Diarrhoea: Drinking plenty of fluids may help manage this side effect.
Indigestion: Stick to a balanced diet and avoid oily food.

Pruvict 1 Tablet contains prucalopride (1 mg), which acts on your body as follows:

Stimulates 5-HT4 receptors: Prucalopride is a selective 5-HT4 receptor agonist. These receptors are found in your gut, and their stimulation increases the activity in your intestines.
Induces release of acetylcholine: By stimulating these receptors, prucalopride indirectly triggers the release of acetylcholine. This neurotransmitter further enhances intestinal motility.
Facilitates gastric emptying: By boosting gut motility, prucalopride helps in the emptying of both solids and liquids from your stomach, which eventually promotes bowel movements.

Pregnancy

Caution is advised while taking Pruvict 1 Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Pruvict 1 Tablet should not be taken while breastfeeding. Always consult your doctor about the potential risks and benefits before starting this medicine.

Alcohol

To ensure safety, it's wise to consult your doctor about alcohol consumption while taking this medicine.

Liver

Caution is necessary while using Pruvict 1 Tablet if you have severe liver problems. Always consult your doctor who can make necessary dosage adjustments or suggest an alternative.

Kidney

This medicine should be used with care if you have severe kidney disease. Your doctor can guide you based on your health status and may adjust the dose accordingly.

Using Machines & Driving

Because of potential dizziness, caution is advised while driving or operating heavy machinery when taking Pruvict 1 Tablet.

Allergy

If you are allergic to prucalopride or any other ingredient in this medicine, avoid using Pruvict 1 Tablet. Inform your doctor about any known allergies for appropriate advice.

Children

Pruvict 1 Tablet is not recommended for use in children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Pruvict 1 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised, especially if patients are above 70 years of age as they might also have liver and kidney issues. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Pruvict 1 Tablet interacts with the following medicines:

Anticholinergics: Medications such as oxybutynin and tolterodine may reduce the effectiveness of prucalopride by opposing its prokinetic action.
CYP3A4 Inhibitors: Drugs like ketoconazole and erythromycin may increase prucalopride levels, potentially enhancing its effects and side effects.
CYP3A4 Inducers: Medications such as rifampicin and carbamazepine may reduce prucalopride levels, diminishing its efficacy.
P-glycoprotein Inhibitors: Drugs like verapamil and cyclosporine can increase prucalopride levels by reducing its elimination.

Drug-Food Interactions

There are no specific interactions between this medication and any food items.

Drug-Disease Interactions

Pruvict 1 Tablet interacts with the following diseases:

Kidney impairment: Individuals with severe kidney impairment should exercise caution when using Pruvict 1 Tablet. The medicine may require dose adjustments in such cases.
Liver impairment: People with severe liver problems need to be careful when taking this medicine as it may necessitate dose modifications.
Intestinal disorders: Pruvict 1 Tablet should not be used by individuals suffering from intestinal disorders such as intestinal perforation, obstruction, or severe inflammatory conditions like Crohn's disease, ulcerative colitis, and toxic megacolon/megarectum. It could exacerbate these conditions.
Hypersensitivity: Patients who have a history of hypersensitivity to prucalopride or any other components of the medication should avoid using Pruvict 1 Tablet as it could lead to allergic reactions.

Daily Dose

Your doctor will determine the daily dose of Pruvict 1 Tablet, based on factors like your condition's severity and your response to treatment. It's crucial to adhere to this prescribed dosage and avoid exceeding it without a doctor's advice.

Over Dose

Exceeding the prescribed dose of Pruvict 1 Tablet may lead to overdose effects such as headache, nausea, abdominal pain, and dizziness. If you accidentally take more than your prescribed dose and experience these or other symptoms, inform your doctor.

Missed Dose

If you forget to take your Pruvict 1 Tablet dose, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never adjust your dosage without consulting your doctor.

Keep Pruvict 1 Tablet in a cool, dry place with temperature below 30°C.
Avoid direct exposure to sunlight and moisture.
Ensure the medicine is out of reach of children.
Always check the expiry date before using the tablet.

Stay hydrated: For conditions like constipation managed by Pruvict 1 Tablet, it's beneficial to drink plenty of fluids each day. This can facilitate bowel movements.
Fibre-rich foods: Incorporate more fibre into your diet. Foods such as fruits, vegetables, and whole grains can stimulate bowel movements and help manage constipation.

Fact Box

Drug Category	5-HT4 Receptor Agonist
Therapeutic Category	Gastroprokinetic Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic Constipation

What is Pruvict 1 Tablet used for?

Pruvict 1 Tablet is used to manage chronic constipation in adults, particularly when laxatives have not provided adequate relief.

How does Pruvict 1 Tablet work in the body?

Pruvict 1 Tablet contains prucalopride which stimulates bowel movements by increasing the activity of the intestines, effectively managing long-term constipation.

Can I take Pruvict 1 Tablet with food?

Take the medicine exactly as prescribed by your doctor.

What are the common side effects of Pruvict 1 Tablet?

Common side effects include headache, nausea, diarrhoea, abdominal pain, reduced appetite, dizziness and indigestion. Inform your doctor if these persist or worsen.

Are there any precautions to consider while taking Pruvict 1 Tablet?

Yes, Pruvict 1 Tablet should be used with caution in patients with severe kidney or liver impairment. It may also affect the ability to drive due to potential dizziness.

Is Pruvict 1 Tablet safe during pregnancy and breastfeeding?

Pruvict 1 Tablet should be avoided during pregnancy and breastfeeding due to potential risks to the baby.

What happens if I miss a dose of Pruvict 1 Tablet?

If you miss a dose, skip it and continue with your regular schedule. Do not take an extra dose to compensate for the missed one.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 9 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Torrent House, Off. Ashram Road, Ahmedabad - 380009, Gujarat, India

Country of origin: INDIA

References

Coremans, G. (2008). Prucalopride: the evidence for its use in the treatment of chronic constipation. PubMed. https://doi.org/10.3355/ce.2008.011
Keating, G. M. (2013). Prucalopride: A review of its use in the management of Chronic constipation. Drugs, 73(17), 1935–1950. https://doi.org/10.1007/s40265-013-0140-1
U.S. Food and Drug Administration. (2018). Other Review(s) Division of Medication Error Prevention and Analysis (DMEPA). Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/210166Orig1s000OtherR.pdf
Prucalopride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB06480

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