Rabezol Dsr 3020 Mg Capsule Sr 10

Rabezol Dsr Capsule 10

Aristo Pharmaceuticals Pvt.ltd

Strip of 10 Units

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MRP ~~₹124.5~~

₹102.09

₹12.45/Units

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Composition

Domperidone (30 Mg) + Rabeprazole (20 Mg)

Rabezol DSR Capsule is used to treat symptoms of acid reflux caused by too much acid, stomach ulcers, and Zollinger-Ellison syndrome (a condition where a pancreatic tumor produces excess acid).

It's also used for short-term treatment of gastroesophageal reflux disease (GERD) symptoms. GERD occurs when the valve at the top of the stomach becomes irritated and damaged from too much stomach acid, causing acid and juices to flow back into the food pipe. This can lead to stomach upset and heartburn, which feels like a burning sensation rising from the stomach to the neck.

Rabezol DSR Capsule should be taken before food or on an empty stomach as food interacts with the absorption of this medicine. If you experience any side effects while on this medication, promptly notify your doctor. Note that it's important to continue taking the medicine for the entire duration prescribed by your doctor to manage your condition effectively.

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Rabezol DSR Capsule is used to manage the following health conditions:

Gastroesophageal reflux disease (Acid reflux): When stomach acid flows back into the food pipe, causing heartburn and discomfort.
Peptic ulcer disease: Open sores in the stomach lining or small intestine, causing pain and discomfort.
Gastric ulcers: Sores that develop on the inside lining of the stomach, leading to pain and indigestion.
Duodenal ulcers: Ulcers that form in the upper part of the small intestine, causing abdominal pain and discomfort.
Acid-related indigestion: This occurs when too much acid is produced in the stomach, leading to symptoms like heartburn and stomach pain.
Administration during Zollinger-Ellison Syndrome: A rare condition where the stomach produces too much acid due to tumours in the pancreas or duodenum.
Heartburn: A burning sensation in the chest caused by acid reflux.
Chest pain: Discomfort or pain in the chest that can be caused by acid reflux.
Difficulty swallowing: The feeling of food getting stuck in the throat or chest.
Nausea and vomiting: Feeling sick to your stomach and the urge to throw up.

Directions for Use of Rabezol Dsr Capsule 10

Here's how to take Rabezol DSR Capsule properly:

Swallow the capsule whole with a glass of water.
Take the capsule on an empty stomach, ideally 1 hour before a meal.
Do not crush or chew the capsule as it will disrupt the sustained-release properties.
Consult your doctor for specific advice on dosage and duration.

Rabezol DSR Capsule is taken orally.

Taking the Rabezol DSR Capsule may cause some side effects. Here are a few common side effects of Rabezol DSR Capsule you may experience:

Diarrhoea: You may have loose stools or frequent bowel movements.
Stomach pain: You may feel discomfort or cramping in your abdomen.
Dryness in the mouth: Your mouth may dry and dehydrate.
Headache: You may experience mild to moderate head pain.
Flatulence: You could experience excessive gas or bloating.
Weakness: You might feel tired or lacking in energy.
Dizziness: You may feel lightheaded or unsteady.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Rabezol DSR Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

To manage these side effects naturally, you can try the following:

Diarrhoea: Stay hydrated by drinking plenty of water and avoiding spicy and oily foods.
Stomach pain: Eat smaller, more frequent meals and avoid consuming large quantities of food at once.
Dryness in the mouth: Sip on water throughout the day to moisten your mouth.
Headache: Rest in a quiet and dark room, apply a cold compress to your forehead, or practise relaxation techniques like deep breathing.
Flatulence: Avoid carbonated drinks, chew slowly and thoroughly.
Weakness: Get enough rest and ensure you're eating a balanced diet with enough nutrients.
Dizziness: Consider taking this medicine at night if it causes you to feel dizzy during the day.

Rabezol DSR Capsule is a combination medication that contains two active ingredients:

Rabeprazole (20 mg): This is a proton pump inhibitor that works by suppressing gastric acid secretion. It does this by blocking a system called gastric H+/K+-ATPase enzyme present in your stomach lining cells. This action leads to an increase in gastric pH, resulting in reduced acidity.
Domperidone (30 mg): As a dopamine-2 receptor antagonist, Domperidone enhances movement in the gastrointestinal tract and speeds up gastric emptying without affecting gastric secretion. It increases contractions in your oesophagus and improves motility between your stomach and small intestine, which helps reduce reflux of stomach contents.

The sustained-release formulation of these components allows for prolonged therapeutic effects. These two ingredients work together in this medicine to effectively manage GERD and other acid reflux disorders.

Pregnancy

Is it safe to use the Rabezol DSR Capsule during pregnancy?

Rabezol DSR Capsule is contraindicated during pregnancy. If you are pregnant or planning to conceive, it's essential to consult with your doctor before starting this medicine.

Breastfeeding

Is it safe to consume Rabezol DSR Capsule during breastfeeding?

Rabezol DSR Capsule is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Is it safe to drink alcohol while taking Rabezol DSR Capsule?

While taking Rabezol DSR Capsule, consider avoiding alcohol as it may exacerbate your symptoms or cause additional discomfort.

Liver

Is it advisable to take Rabezol DSR Capsule when experiencing liver problems?

Caution is advised while taking Rabezol DSR Capsule if you have liver problems. This medicine is not recommended for severe liver diseases. Discuss any liver-related issues with your doctor before beginning this medication.

Kidney

Is it advisable to consume Rabezol DSR Capsule when experiencing kidney problems?

If you have a history of kidney problems, it's a good idea to consult your doctor before taking Rabezol DSR Capsule. Caution is advised in these circumstances.

Using Machines & Driving

Is it safe to operate heavy machinery or drive when using the Rabezol DSR Capsule?

Rabezol DSR Capsule may cause dizziness as a side effect. You should be cautious while driving or operating machines until you know how the medicine affects you.

Allergy

Are there any specific conditions that should be considered before taking the Rabezol DSR Capsule?

This medicine is contraindicated for individuals with known hypersensitivity to rabeprazole, domperidone, or any other components of Rabezol DSR Capsule. If you have any allergies, discuss them with your doctor before starting this medication.

Children

Is Rabezol DSR Capsule suitable for infants or children?

Always consult your doctor before giving this medicine to a child.

Older Patients

Is Rabezol DSR Capsule suitable for older patients?

Older patients should take Rabezol DSR Capsule under medical supervision. They might have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

CYP2C19 Metabolised Medications: Medicines such as diazepam and warfarin, which are metabolised by CYP2C19, can have altered effects when taken with Rabezol DSR Capsule. This is because the active ingredient, rabeprazole, influences the activity of this enzyme.
Heart Medications: Digoxin, a heart medication, can interact with Rabezol DSR Capsule, leading to changes in its effectiveness or an increased risk of side effects.
Antimetabolites: Taking antimetabolites such as methotrexate, especially at high doses, with Rabezol DSR Capsule might lead to an increase in methotrexate levels in your body.
Antiretroviral Medications: Medicines like atazanavir and nelfinavir used for treating HIV may have their effectiveness reduced when taken alongside Rabezol DSR Capsule.

Drug-Food Interactions

Acidic Foods: Acidic foods might interfere with the working of rabeprazole, one of the ingredients in Rabezol DSR Capsule. So it's best to avoid these while taking this medicine.

Drug-Disease Interactions

Liver Disease: If you suffer from liver disease, taking Rabezol DSR Capsule could worsen your condition.
Renal Impairment: If you have kidney problems, you should be cautious while taking this medicine, as it could increase the bioavailability of domperidone, an active ingredient.
Osteoporosis: Long-term use of proton pump inhibitors like rabeprazole present in this medicine could increase your risk of osteoporosis or fractures.
Hypomagnesemia: A rare condition of low magnesium levels in the blood, known as hypomagnesemia, has been reported with prolonged treatment using proton pump inhibitors.

Daily Dose

You should take Rabezol DSR Capsule as directed by your doctor. The dosage can vary depending on factors such as the severity of your condition and how you respond to the medicine. It's vital to adhere to your prescribed dosage.

Over Dose

If you accidentally take more than the recommended dose of Rabezol DSR Capsule, you might experience overdose symptoms like headache, diarrhoea, nausea or abdominal pain. Don't panic, but do inform your doctor about it.

Missed Dose

If you missed a dose take the Rabezol DSR Capsule as soon as possible. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never take an extra dose without consulting with your doctor.

Keep your Rabezol DSR Capsule in a cool, dry place, ideally at room temperature, not exceeding 25°C.
Protect the medicine from direct light and moisture to maintain its efficacy.
Always ensure that it is out of reach of children.
Remember to check the expiry date on the packaging and use the medicine before it expires.

Avoiding spicy and fatty foods can help manage symptoms associated with gastroesophageal reflux disease (GERD), which Rabezol DSR Capsule is prescribed for. Opt for lighter meals with less oil for better digestion.
Limiting alcohol intake can also aid in reducing acid reflux, as alcohol can potentially increase stomach acid production. So, consider cutting down or avoiding alcoholic beverages if you're taking this medication.

Fact Box

Drug Category	Proton Pump Inhibitor, Dopamine-2 Antagonist
Therapeutic Category	Gastrointestinal Agent
Available Dosage Types	Capsule SR
Habit Forming	No
Ailment	GERD, Duodenal Ulcer, Gastric Ulcer

What is Rabezol DSR Capsule used for?

Rabezol DSR Capsule is primarily used to manage symptoms of gastroesophageal reflux disease (GERD), such as heartburn and acid regurgitation.

How does Rabezol DSR Capsule work?

This medicine contains rabeprazole and domperidone. Rabeprazole decreases stomach acid production, while domperidone improves food movement in the gut.

How should I take Rabezol DSR Capsule?

You should swallow the capsule whole with water on an empty stomach, at least 1 hour before a meal as directed by your doctor.

Can I chew or crush the Rabezol DSR Capsule?

No, you shouldn't chew or crush the capsule as it may affect its sustained release properties.

Is it safe to take Rabezol DSR Capsule during pregnancy or while breastfeeding?

No, this medicine is contraindicated during pregnancy or while breastfeeding. Please consult your doctor if you are pregnant or breastfeeding.

What precautions should I take when using this medicine?

If you have liver or kidney problems, or you're elderly, consult with your doctor before taking this medication.

What common side effects might occur with Rabezol DSR Capsule?

Common side effects include headache, diarrhoea, nausea, abdominal pain, and flatulence. If they persist, consult your doctor.

Last Updated On 24 Sep. 2024 | 7:42AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

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References

Cipla Ltd. (n.d.). Rabicip D Capsules (Rabeprazole sodium + Domperidone). Retrieved from https://www.ciplamed.com/content/rabicip-d-capsules
Janssen Research & Development, LLC. (2013, April). A Pharmacokinetics, Pharmacodynamics and Safety Study of Rabeprazole in Newborn Infants with Gastroesophageal Reflux Disease (GERD). In ClinicalTrials.gov. Retrieved from https://clinicaltrials.gov/ct2/show/NCT00855361
Semmanaselvan, K., Mukaddam, Q. I., & Naik, M. (2015, July). An Open Label, Prospective, Single Centre Study to Evaluate the Efficacy and Safety of Fixed Dose Combination of Rabeprazole (Enteric-Coated, EC) 20 mg + Domperidone (Sustained Release, SR) 30 mg Capsule in Treatment of Patients with Laryngopharyngeal Reflux Disease. In PubMed. Retrieved from https://pubmed.ncbi.nlm.nih.gov/26731824/
Shahani, S., Sawant, P., & Dabholkar, P. (2008, April). Rabeprazole plus domperidone: the answer for gastro-esophageal reflux disease. In PubMed. Retrieved from https://pubmed.ncbi.nlm.nih.gov/18828350/

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