Ranolaz Od 1000 Mg Tablet Er 10

Ranolaz Od Tablet 10

Torrent Pharmaceuticals Ltd.

Strip of 10 Units

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Composition

Ranolazine (1000 Mg)

Ranolaz OD Tablet is primarily used for the management of chronic angina pectoris, a condition which causes chest pain. This medicine belongs to a group of medications called anti-anginals.

In addition to managing chronic angina, this medicine is especially used when other antianginal medicines such as nitrates, beta-blockers, or calcium channel blockers have not been able to provide adequate control. It can be used alone or in combination with these medications, providing antianginal and anti-ischemic effects without significantly affecting heart rate or blood pressure.

Before starting this medicine, you should consult your doctor to determine the appropriate dosage and frequency. It's important to let your doctor know about any pre-existing conditions or ongoing medications. If you experience any side effects while on this medication, notify your doctor immediately. To experience optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Ranolaz OD Tablet is used for the following:

Managing chronic angina pectoris
Helping patients with inadequate control from other antianginal medicines
Working as a part of combination therapy with other antianginal medications
Providing antianginal and anti-ischemic effects without significantly affecting heart rate or blood pressure

Directions for Use of Ranolaz Od Tablet 10

Here's how you should take Ranolaz OD Tablet:

Swallow the tablet whole with a glass of water. Don't crush, break or chew it.
If you miss a dose, don't double up on your next one. Just carry on as normal and take the next dose at the regular time.
Always remember to consult your doctor if you're unsure about anything. They can give you specific advice tailored to your situation.

Ranolaz OD Tablet is taken orally.

Taking Ranolaz OD Tablet might lead to the following side effects:

Dizziness
Constipation
Nausea
Headache
QTc prolongation: This means the medicine may cause a minor change in your heart rhythm.
Renal failure: In rare cases, this medicine might affect your kidneys' ability to filter waste from your blood.
Hepatic injury: This refers to potential damage to your liver.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Ranolaz OD Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Constipation: Try increasing your intake of fibre and fluids while you're taking this medicine.
Dizziness: Consider taking this medicine at bedtime if it makes you feel dizzy during the day.

Ranolaz OD Tablet contains Ranolazine (1000 Mg), which works on your body as follows:

Inhibition of Late Inward Sodium Current: Ranolazine selectively inhibits the late inward sodium current (INa) in the cells of your heart. This current is responsible for the accumulation of sodium and calcium inside the cells, which can lead to heart issues and angina.
Prevention of Sodium and Calcium Accumulation: By inhibiting the late INa, ranolazine prevents the pathologic accumulation of sodium and calcium during heart muscle ischemia. This action helps to improve the relaxation of the heart muscle and reduces the stiffness of the left ventricle of your heart.
Minimal Effects on Cardiac Conduction: Ranolazine does not significantly affect the electrical conduction system of your heart. This means that it has minimal impact on your heart rate or blood pressure.

Pregnancy

Caution is advised while taking Ranolaz OD Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Breastfeeding women are advised to exercise caution when taking Ranolaz OD Tablet. Always discuss with your doctor about potential risks and benefits before starting this medication.

Alcohol

It's always wise to consult your doctor for advice on this topic.

Liver

Ranolaz OD Tablet is contraindicated in patients with clinically significant hepatic impairment. If you have liver problems, discuss them with your doctor before starting Ranolaz OD Tablet. This medicine may affect liver function.

Kidney

For patients with severe renal impairment, the recommended starting dose of Ranolaz OD Tablet is lower. If you have a history of kidney problems, it's important to consult your doctor before starting this medicine.

Using Machines & Driving

Ranolaz OD Tablet may cause dizziness. Be cautious while driving or operating machinery until you know how this medicine will affect you.

Allergy

Ranolaz OD Tablet is contraindicated in patients with known hypersensitivity to ranolazine or any of its components. Always let your doctor know about any allergies you may have before starting this medicine.

Children

Ranolaz OD Tablet should not be given to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Ranolaz OD Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age as they might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Ranolaz OD Tablet interacts with the following medicines:

Antihypertensives: Ranolaz OD Tablet can interact with medicines like diltiazem and verapamil. This interaction can increase the concentration of ranolazine in your blood.
Anticonvulsants: Medicines like rifampin can reduce the effectiveness of Ranolaz OD Tablet by decreasing its levels in your body.
Cardiac glycosides: Ranolaz OD Tablet may increase levels of medicines like digoxin, which could affect their action.

Drug-Food Interactions

Certain foods can interact with Ranolaz OD Tablet:

Grapefruit: Consuming grapefruit or grapefruit juice while taking Ranolaz OD Tablet may increase its levels in your body and lead to increased side effects.

Drug-Disease Interactions

Ranolaz OD Tablet interacts with the following diseases:

Liver Disease: If you have significant liver disease, your body might not metabolise Ranolaz OD Tablet properly, leading to increased levels of the medicine.
Electrolyte Imbalance: If you have low potassium or magnesium levels, take caution when starting Ranolaz OD Tablet as it can prolong the QTc interval, a measure of heart rhythm.

Daily Dose

Your doctor will prescribe the daily dose of Ranolaz OD Tablet based on your individual health condition and how you respond to the medicine. It's crucial not to alter this dosage without consulting your doctor.

Over Dose

If you accidentally take more Ranolaz OD Tablet than prescribed, you might feel light-headed or experience vomiting. In such cases, get in touch with your doctor for advice.

Missed Dose

If you forget to take a dose of Ranolaz OD Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and keep to your regular schedule. Never increase your dosage unless advised by your doctor.

Store your Ranolaz OD Tablet at room temperature, ideally below 25°C.
Keep your medicine away from direct light and moisture, preserving it in its original packaging.
Always keep this medicine out of the reach of children.
Remember to use the tablet before its expiry date.

If you're taking Ranolaz OD Tablet for angina, try to maintain a low-fat diet. This can help manage your cholesterol levels and support heart health.
Engage in light physical activity regularly, as guided by your doctor. This might help improve cardiovascular fitness without straining your heart.

Fact Box

Drug Category	Late INa Inhibitor
Therapeutic Category	Antianginal
Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Chronic Angina Pectoris

What is Ranolaz OD Tablet used for?

Ranolaz OD Tablet is used to manage chronic angina, a type of chest pain. It's particularly effective for patients whose symptoms are not adequately controlled by other medications.

How does Ranolaz OD Tablet work?

Ranolaz OD Tablet contains ranolazine which reduces chest pain by inhibiting an abnormal flow of sodium and calcium in heart cells, thereby preventing harmful accumulation during heart muscle stress.

Can I take Ranolaz OD Tablet with food?

You must take the medicine as directed by your doctor.

What should I do if I accidentally skip a dose?

If you miss a dose, just take the next one at its scheduled time. Do not double up on doses to make up for the missed one.

Are there any side effects of Ranolaz OD Tablet?

Some people may experience side effects like dizziness, headache, constipation, and nausea. If these persist or worsen, consult your doctor immediately.

Can I drive after taking this medicine?

As Ranolaz OD Tablet may cause dizziness in some people, it's best to see how it affects you before you drive or operate machinery after taking it.

Are there any foods or drinks I should avoid while taking this medicine?

Yes, while on this medication, avoid consuming grapefruit and grapefruit juice as they might interfere with how the medicine works.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Torrent House, Off. Ashram Road, Ahmedabad - 380009, Gujarat, India

Country of origin: INDIA

References

CV Therapeutics. (2006). Highlights of prescribing information [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/021526s007lbl.pdf
DailyMed - RANOLAZINE- extended-release tablet. (n.d.). https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=f0cbc60a-5ef0-4ba9-9863-b065360bca21
Ranolazine: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00243
Ranolazine: MedlinePlus Drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a606015.html
PubChem. (n.d.). Ranolazine. National Center for Biotechnology Information. https://pubchem.ncbi.nlm.nih.gov/compound/Ranolazine

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