Rcifax 400 Mg Tablet 10

Rcifax 400 Tablet 10

Lupin Ltd

Strip of 10 Units

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MRP ~~₹469.55~~

₹385.03

₹46.96/Units

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Composition

Rifaximin (400 Mg)

Strength:

200 MG 550 MG 400 MG

Rcifax 400 Tablet is a prescription medication for treating gastrointestinal infections such as travellers' diarrhoea (TD). It is a gastrointestinal infection characterised by watery diarrhoea, abdominal cramps, and nausea.

The tablet is also used to manage hepatic encephalopathy (HE). It is a condition caused by liver dysfunction, leading to the buildup of toxins in the brain. The symptoms of HE include confusion, cognitive impairment, and personality changes.

Rcifax 400 also treats irritable bowel syndrome (IBS) with diarrhoea in adults. It is a gastrointestinal disorder characterised by watery stools, the urgency to have bowel movements, abdominal cramping, bloating, and gas.

The composition of Rcifax 400 Tablet includes Rifaximin 400 mg as the active ingredient. It is effective against Escherichia coli (E.Coli) and many other gut pathogens. It is not used for respiratory or urinary tract infections.

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Hepatic encephalopathy: Rcifax 400 Tablet reduces the risk of overt hepatic encephalopathy (HE) recurrence in adults. It reduces ammonia levels in the intestines, thereby alleviating neurological symptoms associated with liver dysfunction and the buildup of toxins in the brain.
Traveller’s diarrhoea: The medication also alleviates symptoms of diarrhoea and abdominal discomfort in traveller’s diarrhoea. It targets and suppresses the growth of bacteria in the intestine.
Irritable bowel syndrome (IBS) with diarrhoea: Rcifax 400 is also used to control the diarrhoeal phase of IBS.

Directions for Use of Rcifax 400 Tablet 10

Swallow Rcifax 400 Tablet whole with a glass of water.
Do not crush or chew the tablet, as this may affect the way the medication is absorbed in the body.
Take the tablet at fixed times each day to maintain a consistent level of medication.
Do not alter the dosage or increase the tablet frequency beyond the prescribed instructions.

Rcifax 400 Tablets are administered orally.

Rcifax 400 Tablet is considered safe and effective when a doctor prescribes it. However, some people may experience mild to severe side effects. The common side effects include:

Nausea
Dizziness
Excessive tiredness
Headache
Stomach pain

Managing the Side Effects:

Most of the side effects are temporary and harmless, and get resolved by discontinuing the tablet. These may not require medical attention. To combat abdominal discomfort, take this tablet with food. If you experience severe or persistent side effects from this tablet, consult your doctor.

The active ingredient in Rcifax 400 Tablet, Rifaximin, is a broad-spectrum antibiotic. It can kill bacteria and inhibit their growth.

It specifically targets and inhibits the enzyme, which is essential for bacterial growth. It also effectively disrupts the reproduction of susceptible bacteria.

The tablet remains primarily in the gastrointestinal tract without entering the bloodstream significantly.

Pregnancy

Rcifax 400 may be unsafe during pregnancy. Although, there is no evidence that the tablet harms a growing foetus. A few animal studies have shown its harmful effects on the foetus. Consult with your doctor to evaluate your specific situation and make an informed decision regarding the use of Rcifax during pregnancy.

Breastfeeding

No evidence suggests that Rcifax 400 is excreted in human milk. It might be safe to have it while breastfeeding. Still, it is recommended to consult your doctor before taking this medication.

Alcohol

It is recommended to avoid alcohol while taking Rcifax 400. Alcohol can increase dizziness and tiredness due to the medication.

Liver

Patients with severe liver disease should cautiously use Rcifax 400 Tablet. If you have a severe liver problem, consult your doctor about the dose before taking the medication. Dose adjustments may be required.

Kidney

Rcifax 400 is safe to be used for patients with kidney impairment. No dose adjustments are required. However, if you have any concerns about taking the tablet with kidney disease, it is better to consult a doctor.

Using Machines & Driving

Avoiding any attentive task is recommended if you experience dizziness or tiredness after taking Rcifax 400 Tablet. The medication can affect your mental or physical abilities required to use machines or drive a vehicle.

Allergy

If you are allergic to rifaximin, you should not take Rcifax 400 Tablet. Read the label and check the ingredients before using the tablet to avoid allergic reactions. The allergic reactions to the tablet may include skin inflammation and swelling.

Children

Rcifax 400 Tablets are not intended for children under 12 years of age. Please consult your doctor before giving it to your child.

Older Patients

Older adults may be more susceptible to the side effects of the medication. Those with severe liver disease must not take this medication without a doctor's prescription. Moreover, older patients may also take other medications or supplements that interact with Rcifax 400 Tablets. Therefore, consult your doctor before taking the tablet.

Drug-Drug Interactions

The Rcifax 400 Tablet can interact with medications, including:

Immune system affecting medications such as cyclosporine
Blood thinners such as warfarin

Drug-Disease Interactions

The Rcifax 400 Tablet can interact with diseases, including:

Colitis (inflammation of the colon)
Liver disease

Daily Dose

The recommended daily dose of Rcifax 400 Tablet is one tablet taken once a day, with food. The dosage may change based on individual factors such as the severity of the condition and response to treatment. It is important to follow the prescribed dosage and consult your doctor before exceeding it.

Over Dose

If you or someone else takes an excessive amount of Rcifax 400 Tablet by accident, it is essential to take immediate medical attention from your doctor or nearby hospital. Symptoms of an overdose include nausea, dizziness, excessive tiredness, headache and stomach pain.

Missed Dose

If you forgot to take Rcifax 400, take it as soon as you remember. If the time for the next dosage is close, it is recommended to skip the missed one and resume your regular dosage pattern. Never increase your dosage without consulting your doctor.

Store this medicine at a temperature below 30 ºC.
Protect it from light and moisture.
Keep Rcifax 400 Tablet away from children.
Do not use this medicine after the expiry date has passed.

Limit dietary protein to reduce the production of ammonia in the body. Focus on consuming high-quality protein sources such as lean meats, poultry, fish, dairy products, and plant-based proteins.
Reduce salt intake to minimise fluid retention and swelling.
Avoid processed and packaged foods.
Increase your fibre intake through whole grains, fruits, vegetables, and legumes.
Avoid alcohol, which can further damage the liver and worsen hepatic encephalopathy symptoms.

Fact Box

Drug Category	Antimicrobial drug
Therapeutic Category	Antidiarrhoea
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Treatment of traveller's diarrhoea, management of hepatic encephalopathy and treatment of irritable bowel syndrome with diarrhoea in adults.

When should I take Rcifax 400 Tablet?

Rcifax 400 Tablet is best taken with food to avoid its side effects.

Is Rcifax 400 an antibiotic?

Yes, Rcifax 400 is an antibiotic effective against E.coli in the gastrointestinal tract.

Is Rcifax 400 safe for the liver?

Rcifax 400 Tablet is safe for patients with mild to moderate liver impairment. However, those with severe liver impairment should take this medication only when prescribed.

Is Rcifax 400 a strong antibiotic?

Rcifax 400 Tablet is a broad-spectrum antibiotic, but its strength may vary depending on the specific infection being treated. It is generally considered effective for hepatic encephalopathy, travellers' diarrhoea and irritable bowel syndrome (IBS) with diarrhoea.

How fast does Rcifax 400 work?

The onset of action for the Rcifax 400 Tablet can vary depending on the treated condition. It is generally expected to start working within a few hours to a few days after initiating treatment.

What to avoid when taking Rcifax 400?

You may continue having a normal diet unless instructed by a doctor. When taking Rcifax 400 Tablet, it is generally recommended to avoid alcohol. It can increase the risk of side effects.

Who should not take Rcifax 400?

Rcifax 400 Tablet should not be taken by individuals who are hypersensitive or allergic to rifaximin or any other medication components. It is also not recommended for those with severe liver impairment.

How many times should I take Rcifax 400?

The dosage and frequency of Rcifax 400 Tablet are determined by a doctor based on your specific condition. It is important to follow the recommended dosage provided by your doctor. Typically, it is taken once daily.

Last Updated On 09 Feb. 2024 | 11:28AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Kalpataru Inspire, 3rd Floor, Off. Western Express Highway, Santacruz (East), Mumbai

Country of origin: INDIA

References

Robertson, K. and Nagalli, S. (2022) "Rifaximin", StatPearls Publishing, p. Available at: https://www.ncbi.nlm.nih.gov/books/NBK562329/ (Accessed: 1 June 2023).
Drugs, H. (2023) Rifaximin: MedlinePlus Drug Information, Medlineplus.gov. Available at: https://medlineplus.gov/druginfo/meds/a604027.html (Accessed: 1 June 2023).
cdscoonline.gov.in. (n.d.). CDSCO. [online] Available at: https://cdscoonline.gov.in/CDSCO/Drugs.
Tripathi, K.D. (2019). Essentials of medical pharmacology. New Delhi: Jaypee Brothers Medical Publishers.

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