Renocrit 4000 Injection 0.4ml

Zydus Cadila

Pre-filled syringe of 0.4 ML

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MRP ~~₹1307.00~~

₹1045.60

₹3267.5/ML

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Prescription required for this medicine

Store in refrigerator or (2^o - 8^o C) Do Not Freeze

Composition

Recombinant Human Erythropoietin Alfa (4000 Iu)

Renocrit 4000 Injection is used for the treatment of anemia associated with chronic renal failure in patients on dialysis. This medication stimulates the production of red blood cells, alleviating fatigue and improving oxygen delivery throughout the body. It belongs to the class of erythropoiesis-stimulating agents (ESAs).

This injection is also used in the treatment of symptomatic renal anaemia in patients not yet undergoing dialysis. It is also used for the treatment of symptomatic anaemia in adult patients with receiving chemotherapy.

Consult your healthcare provider before starting this medication, as the dosage and treatment duration depend on your condition and medical history. Inform your doctor about pre-existing conditions, ongoing medications, or allergies to ensure safe and effective use.

Renocrit 4000 Injection is prescribed for:

Anaemia due to chronic kidney disease (dialysis and non-dialysis patients)
Anaemia in adults undergoing chemotherapy for non-myeloid malignancies
Anaemia in patients scheduled for elective surgery to reduce the need for blood transfusions

Directions for Use of Renocrit 4000 Injection 0.4ml

This injection is administered by a healthcare professional.
Follow your doctor’s instructions regarding hydration and other supportive measures.

Renocrit 4000 Injection is administered subcutaneously (under the skin) or intravenously (into a vein).

Side Effects of Renocrit 4000 Injection 0.4ml

The common side effects of Renocrit 4000 Injection include:

Headache
Nausea
Vomiting
Hypertension (high blood pressure)
Injection site reactions

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of this Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Nausea or vomiting: Stay hydrated and consume small, frequent meals.
Injection site reactions: Apply a cold compress to the injection site to alleviate swelling or pain.
Hypertension: Monitor blood pressure regularly to manage hypertension effectively.

How Renocrit 4000 Injection 0.4ml Works?

Renocrit 4000 Injection contains Recombinant Human Erythropoietin Alfa (4000 IU), which acts as follows:

It mimics the action of erythropoietin, a natural hormone produced by the kidneys. It works by stimulating the bone marrow to produce red blood cells, treating anaemia caused by reduced erythropoietin levels.

Pregnancy

Discuss the potential risks and benefits with your doctor before using Renocrit 4000 Injection during pregnancy.

Breastfeeding

It is not known whether erythropoietin alfa passes into breast milk. Inform your doctor before taking this injection.

Alcohol

Limit alcohol consumption when taking Renocrit 4000 Injection, as it may exacerbate anaemia and other health conditions.

Liver

Patients with liver diseases should use Renocrit 4000 Injection cautiously. Regular liver function tests are recommended.

Kidney

This medication is primarily used in kidney disease patients. Regular monitoring of kidney function is crucial during treatment.

Using Machines & Driving

Avoid driving or operating machinery if you experience dizziness, headache, or fatigue after the injection.

Allergy

If you have a known allergy to erythropoietin or any ingredients in Renocrit 4000 Injection, avoid using this medication and inform your doctor immediately.

Children

Renocrit 4000 Injection is not recommended for children uner 18 years unless specifically prescribed by a doctor.

Older Patients

Older patients may require careful monitoring due to a higher risk of side effects, especially cardiovascular events.

Interactions of Renocrit 4000 Injection 0.4ml

Drug-Drug Interactions

Renocrit 4000 Injection can interact with medications including:

Antihypertensives: Monitor blood pressure when taking propanolol, atenolol or any other blood pressure medication as Renocrit 4000 Injection may increase blood pressure.
Iron Supplements: Enhances efficacy when used together. Monitor iron levels regularly.

Drug-Food Interactions

No significant food interactions are known, but maintaining a balanced diet can support overall treatment.

Drug-Disease Interactions

Renocrit 4000 Injection can interact with conditions including:

Hypertension: This injection can increase blood pressure. It must be controlled before starting treatment.
Thromboembolic Events: Patients with a history of blood clots require careful monitoring.

Daily Dose

The daily dosage of Renocrit 4000 Injection depends on your condition and response to treatment. Your doctor will determine the appropriate dose based on your haemoglobin levels and therapeutic goals.

Over Dose

Overdosing of this injection may lead to high haemoglobin levels, increasing the risk of cardiovascular complications. Seek immediate medical attention if an overdose is suspected.

Missed Dose

If a dose is missed, consult your doctor for further instructions. Do not double the dose.

Store at 2°C to 8°C. Do not freeze.
Protect from light and keep the syringe in its original packaging.
Keep out of reach of children.

Maintain a diet rich in iron, folic acid, and vitamin B12 to support red blood cell production.
Engage in light to moderate exercise to enhance energy levels but avoid overexertion.

Fact Box

Drug Category	Erythropoiesis-Stimulating Agent (ESA)
Therapeutic Category	Anti-anaemic
Available Dosage Types	Injection
Habit Forming	No
Ailment	Anaemia in chronic kidney disease, chemotherapy-induced anaemia, surgical anaemia

What is Renocrit 4000 Injection used for?

This injection is used to treat anaemia caused by chronic kidney disease, chemotherapy, or surgery.

How does Renocrit 4000 Injection work?

This injection stimulates the production of red blood cells by mimicking the natural hormone erythropoietin.

Can I use Renocrit 4000 Injection during pregnancy?

Consult your doctor to evaluate the risks and benefits of using this medication during pregnancy.

What are the side effects of Renocrit 4000 Injection?

The common side effects include headache, nausea, and hypertension.

How should I store Renocrit 4000 Injection?

Store it at 2°C to 8°C, away from light and out of reach of children.

Can I drink alcohol while on Renocrit 4000 Injection?

Limit alcohol consumption to avoid complications related to anaemia. Always discuss with your doctor.

What should I do if I miss a dose of Renocrit 4000 Injection?

Contact your healthcare provider for advice. Never double the dose to make up for a missed one.

Last Updated On 23 Jan. 2025 | 3:19PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

5V74+4P2, Jay Prakash Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

Beta, E. (n.d.). Recormon pre-filled syringes. Roche.Com. Retrieved January 15, 2025, from https://assets.roche.com/f/170883/x/543f83bbb2/recormon-pi-feb-2022.pdf
(N.d.). Gov.Rw. Retrieved January 15, 2025, from https://rwandafda.gov.rw/wp-content/uploads/2024/02/REPOITIN
Binocrit 1 000 IU/0.5 mL solution for injection.(N.d.). Europa.Eu. Retrieved January 15, 2025, from https://www.ema.europa.eu/en/documents/product-information/binocrit-epar-product-information_en.pdf

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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