Rioci 05 Mg Tablet 10

Rioci 0.5 Tablet 10

Msn Laboratories Ltd

Strip of 10 Units

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MRP ~~₹260.8~~

₹213.86

₹26.08/Units

18% off

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Composition

Riociguat (0.5 Mg)

Strength:

1 MG 1.5 MG 2.5 MG 0.5 MG

Rioci Tablet is used primarily to manage chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH). It belongs to a group of medicines known as soluble guanylate cyclase (sGC) stimulators.

This medication also aids in reducing the strain on your heart by improving blood flow in your lungs. It takes effect by relaxing specific blood vessels, which helps decrease the workload on your heart and enhance your overall health condition.

Before starting this medicine, it's important to inform your doctor about any pre-existing conditions and ongoing medications. Any side effects noticed during the course of this medicine should be reported to your doctor promptly. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Rioci Tablet is used for the following:

Management of chronic thromboembolic pulmonary hypertension (CTEPH) in patients unsuitable for surgery or those experiencing persistent or recurrent symptoms after surgical treatment
Enhancing exercise capacity in individuals with pulmonary arterial hypertension (PAH)
Delaying clinical worsening and improving WHO functional class in cases of pulmonary arterial hypertension (PAH)

Directions for Use of Rioci 0.5 Tablet 10

Here's how you should take Rioci Tablet:

Swallow the tablet whole with a glass of water.
Do not chew, crush, or break the tablet.
Avoid doubling up on doses if you miss one; simply take the next dose at its scheduled time.
Always consult your doctor before making any changes to your dosage.

Rioci Tablet is taken orally.

Rioci Tablet may have the following common side effects:

Headache
Dizziness
Dyspepsia: This refers to indigestion or an upset stomach.
Nausea
Diarrhoea
Hypotension: This is a medical term for low blood pressure.
Peripheral Oedema: This means swelling in your limbs.
Anaemia: This is a condition where your body lacks enough healthy red blood cells.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Rioci Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips to help manage certain side effects:

Dyspepsia: Trying to take Rioci Tablet with meals might help manage this feeling of indigestion.
Hypotension: If you feel dizzy or faint after taking this medicine, it may be useful to take it just before bedtime.

Rioci Tablet contains riociguat (0.5 mg), which works on your body in the following ways:

Stimulates Soluble Guanylate Cyclase (sGC): Riociguat stimulates an enzyme called soluble guanylate cyclase in your cardiopulmonary system. This enzyme plays a significant role in managing your blood pressure and maintaining your heart health.
Increases Production of cGMP: By stimulating sGC, riociguat increases the production of cyclic guanosine monophosphate (cGMP). This compound helps in relaxing and widening your blood vessels, leading to improved blood flow.
Reduces Pressure and Strain: The enhanced cGMP production leads to vasodilation, or the widening of blood vessels, in the pulmonary arteries. This process reduces the pressure in your lungs and decreases the strain on the right side of your heart.

Pregnancy

Rioci Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, discuss this with your doctor before taking this medicine.

Breastfeeding

Consult your doctor to understand the potential risks and benefits before using Rioci Tablet while breastfeeding.

Alcohol

There's no known interaction of Rioci Tablet with alcohol. However, it's best to discuss this with your doctor.

Liver

Caution is advised while taking Rioci Tablet in case of mild to moderate liver impairment. It is not recommended for severe liver diseases. If you have liver problems, discuss them with your doctor before starting this medicine.

Kidney

Caution is advised before taking Rioci Tablet if you have any kidney problems. Consult your doctor before using this medicine.

Using Machines & Driving

Rioci Tablet may cause dizziness, which could affect your ability to drive or operate machinery. Exercise caution until you know how the medicine affects you.

Allergy

If you're allergic to riociguat or any other components of Rioci Tablet, avoid using this medicine and consult your doctor.

Children

Rioci Tablet should not be given to children under 18 years of age without medical advice.

Older Patients

Older patients should use Rioci Tablet under medical supervision as they might be more prone to its side effects and may have liver or kidney issues.

Drug-Drug Interactions

Rioci Tablet interacts with the following medicines:

Nitrates and Nitric Oxide Donors: Medicines such as isosorbide dinitrate or nitroglycerin may interact with Rioci Tablet, potentially increasing the risk of low blood pressure (hypotension).
Phosphodiesterase inhibitors (PDE-5 inhibitors): Medications like sildenafil or tadalafil may have interactions with Rioci Tablet, increasing the chance of experiencing a drop in blood pressure.
Antacids: Antacids, like aluminium hydroxide, can reduce the absorption of Rioci Tablet if taken together.
Anticoagulants: There's a heightened bleeding risk when Rioci Tablet is taken with anticoagulants like warfarin.

Drug-Food Interactions

Drug-Disease Interactions

Rioci Tablet interacts with the following diseases:

Hypotension: Patients with low blood pressure should exercise caution while taking this medicine as it could further lower blood pressure levels.
Renal Impairment: People suffering from kidney problems may need to adjust their dose of Rioci Tablet under a doctor's guidance.
Hepatic Impairment: Caution is advised for patients with mild to moderate liver disease when using this medicine; it is not recommended for those with severe liver impairment.

Daily Dose

Rioci Tablet should be taken as directed by your doctor. The dosage is likely to vary based on factors like the seriousness of your condition and how you respond to the medication. Always stick to the prescribed dosage and never increase it without consulting your doctor.

Over Dose

Accidental overdosing on Rioci Tablet can cause symptoms similar to its common side effects, such as headaches, dizziness and nausea. If you've consumed more than the prescribed limit, inform your doctor without delay.

Missed Dose

If you've forgotten to take a dose of Rioci Tablet, take it as soon as you remember. However, if it's near time for your next scheduled dose, skip the missed one and carry on with your regular dosage schedule. Don't increase your dosage without talking to your doctor.

Store Rioci Tablet at room temperature, ideally below 30°C.
Keep the medicine in its original packaging to protect it from light and moisture.
Always keep Rioci Tablet out of reach of children.
Make sure you use the medicine before its expiry date.

If you have pulmonary hypertension, try to minimise your salt intake. High salt levels can make your body retain water, which can put extra strain on your heart.
Regular exercise can help improve your cardiovascular health. However, always discuss with your doctor what activities are safe for you before starting any new physical regimen.

Fact Box

Drug Category	sGC Stimulator
Therapeutic Category	Antihypertensive
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension

What is Rioci Tablet used for?

Rioci Tablet is primarily used to manage chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary arterial hypertension (PAH).

How does Rioci Tablet work?

It contains riociguat, which helps relax blood vessels in the lungs, improving blood flow and reducing strain on the heart.

Can I take Rioci Tablet with food?

You must take the medicine as directed by your doctor.

Is it safe to use Rioci Tablet during pregnancy?

No, Rioci Tablet can harm your baby if you're pregnant. Consult your doctor about effective contraception while using this medicine.

Are there any side effects of Rioci Tablet?

Side effects may include headaches, dizziness, indigestion, nausea, diarrhoea, low blood pressure, swelling in limbs and anaemia.

Can I take other medicines while using Rioci Tablet?

Certain medicines might interact negatively with Rioci Tablet. Always inform your doctor about all medications you are taking.

How should I store my Rioci Tablet?

Store it at room temperature between 15°C to 30°C in a tightly closed container, protected from moisture and light.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

MSN House, Plot No: C-24, Industrial Estate, Sanathnagar, Hyderabad, Telangana 500018

Country of origin: INDIA

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. (n.d.). https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/204819s006lbl.pdf
ANNEX I SUMMARY OF PRODUCT CHARACTERISTICS. (n.d.). https://www.ema.europa.eu/en/documents/product-information/adempas-epar-product-information_en.pdf
WHAT IS RIOCIGUAT? (n.d.). Retrieved November 19, 2024, from https://phassociation.org/wp-content/uploads/2018/04/Patients-Treatment-Riociguat-4-12-18.pdf
Riociguat: Uses, Interactions, Mechanism of Action | DrugBank Online. (2016). Drugbank.com; DrugBank. https://go.drugbank.com/drugs/DB08931

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