Rivarex 10 Tablet 10

Chemo Health Care Pvt Ltd

Strip of 10 Units

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MRP ~~₹330~~

₹270.6

₹33.00/Units

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Composition

Rivaroxaban (10 Mg)

Strength:

2.5 MG 20 MG 15 MG 10 MG

Rivarex 10 Tablet 10 is primarily used to prevent and manage blood clots in your body. This medicine falls under the category of anticoagulants, specifically known as direct factor Xa inhibitors.

In addition to its main use, this medicine is also utilised in preventing stroke and systemic embolism in adults with a condition called non-valvular atrial fibrillation. It's useful in treating deep vein thrombosis (DVT) and pulmonary embolism (PE), as well as in avoiding the recurrence of these conditions after initial treatment. Moreover, it's prescribed to prevent venous thromboembolism (VTE) in patients undergoing knee or hip replacement surgery.

Remember to take this medicine exactly as your doctor prescribes. It's essential to inform your doctor about any ongoing medicines or pre-existing diseases before you start using it. If you experience any side effects, let your doctor know immediately. For optimal results, continue taking this medicine for the duration prescribed by your doctor.

Rivarex 10 Tablet 10 is used for the following:

Preventing stroke and systemic embolism in patients with non-valvular atrial fibrillation
Managing deep vein thrombosis (DVT) and pulmonary embolism (PE)
Stopping recurrent DVT and PE after initial management
Lowering the risk of venous thromboembolism (VTE) in patients following knee or hip replacement surgery

Directions for Use of Rivarex 10 Tablet 10

Here are some guidelines to follow while taking Rivarex 10 Tablet 10:

Swallow the tablet whole with a glass of water.
Do not crush or chew the tablet.
It is crucial not to stop taking this medicine without consulting your doctor first.

Rivarex 10 Tablet 10 is taken orally.

Rivarex 10 Tablet 10 may have the following side effects:

Bleeding complications that could include nosebleeds, blood in your urine, heavy periods for women, or bleeding from the gastrointestinal tract
A decrease in the total amount of red blood cells or haemoglobin in your blood
Nausea
Swelling in your limbs caused by fluid build-up
Dizziness
Headache

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolves on discontinuing the use of Rivarex 10 Tablet 10. However, if you experience any serious side effects or worsening symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Nausea: Take Rivarex 10 Tablet 10 with light food to lessen this effect.
Dizziness: Avoid activities your doctor has advised against and follow their recommendations.

Rivarex 10 Tablet 10 contains rivaroxaban (10 mg). It impacts your body in the following ways:

Selective Factor Xa Inhibition: This medicine works by selectively blocking an enzyme in your body known as factor Xa, which plays a critical role in blood clot formation.
Decreased Thrombin Generation: By inhibiting factor Xa, rivaroxaban reduces the generation of thrombin, a protein that causes blood to clot.
Direct Factor Xa Inhibition: Unlike some other anticoagulants, rivaroxaban directly inhibits factor Xa, without needing any additional substances like antithrombin III. This direct action makes it efficient in preventing clot formation.

Pregnancy

Caution is advised while taking Rivarex 10 Tablet 10 if you are pregnant due to potential for obstetric hemorrhage and/or emergent delivery. It is best to consult your doctor before taking this medicine.

Breastfeeding

Rivarex 10 Tablet 10 is not recommended for breastfeeding women as rivaroxaban, the active ingredient in this medicine, is secreted in human milk. You should consult your doctor to understand the potential risks and benefits.

Alcohol

There's no known interaction between Rivarex 10 Tablet 10 and alcohol. However, as a general rule, it's always wise to discuss with your doctor about any alcohol consumption while on medication.

Liver

Patients with liver impairment should avoid taking Rivarex 10 Tablet 10, especially if they have any hepatic disease associated with coagulopathy. If you have liver problems, discuss them with your doctor before starting this medication.

Kidney

For those with renal impairment, the use of Rivarex 10 Tablet 10 is not recommended, particularly if your creatinine clearance (CrCl) is less than 15 mL/min. Discussing with your doctor will help evaluate whether this medicine suits you.

Using Machines & Driving

Dizziness is a reported side effect of this medicine. If you experience dizziness after taking it, avoid driving or operating heavy machinery.

Allergy

Rivarex 10 Tablet 10 should not be taken if you have a severe hypersensitivity reaction to rivaroxaban or any other ingredients of the tablet. Please consult your doctor if you have known allergies.

Children

Rivarex 10 Tablet 10 is generally not recommended for use in children below 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Rivarex 10 Tablet 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Rivarex 10 Tablet 10 interacts with the following medicines:

Antifungals: Medicines like ketoconazole and itraconazole can increase rivaroxaban levels in your body, which may raise the risk of bleeding.
Antibiotics: Medicines such as rifampin can decrease rivaroxaban levels, reducing its effectiveness.
Anticoagulants: Taking other blood thinners, like warfarin or heparin, alongside Rivarex 10 Tablet 10 may increase your risk of bleeding.
NSAIDs: Medicines like ibuprofen can increase the risk of bleeding when taken with this medicine.
Thrombolytics and antiplatelet agents: These medicines, which include clopidogrel and tirofiban, can potentially increase your risk of bleeding when used alongside Rivarex 10 Tablet 10.

Drug-Food Interactions

No specific food interactions have been identified for Rivarex 10 Tablet 10.

Drug-Disease Interactions

Rivarex 10 Tablet 10 interacts with the following diseases:

Renal impairment: If you have a condition that impairs your kidney function, using Rivarex 10 Tablet 10 could increase your risk of bleeding.
Hepatic impairment: If you have liver disease (especially Child-Pugh B and C hepatic impairment), this medicine should be avoided due to potentially increased risks.

Daily Dose

Your daily dose of Rivarex 10 Tablet 10 will be determined by your doctor, who will consider factors such as your condition's severity and your response to the medicine. It's crucial to stick to this prescribed dose and not alter it without consulting your doctor.

Over Dose

If you accidentally take more Rivarex 10 Tablet 10 than prescribed, you might experience symptoms such as unusual bruising or prolonged bleeding. If you notice any of these signs, do inform your doctor.

Missed Dose

If you miss a dose of Rivarex 10 Tablet 10, take it as soon as you remember. But if it's nearly time for your next dose, just skip the missed one and continue with your regular schedule. Never double up on doses without your doctor's advice.

Store Rivarex 10 Tablet 10 at room temperature, ideally below 30°C.
Keep the tablet in its original packaging to protect it from moisture.
Avoid exposure to direct sunlight or heat sources.
Always keep this medicine out of reach of children.
Ensure you use the tablet before its expiry date.

Make sure to stay well-hydrated. This is important as dehydration can increase the risk of blood clotting, which Rivarex 10 Tablet 10 helps manage.
Regular low-intensity exercise such as walking or swimming can help improve circulation and reduce the risk of blood clots. Please consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Direct Factor Xa Inhibitor
Therapeutic Category	Anticoagulant
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Stroke Prevention, Deep Vein Thrombosis, Pulmonary Embolism

What is Rivarex 10 Tablet 10 used for?

Rivarex 10 Tablet 10 is used to prevent and manage blood clots in conditions like non-valvular atrial fibrillation, deep vein thrombosis, pulmonary embolism, and after knee or hip replacement surgery.

How does Rivarex 10 Tablet 10 work?

The tablet contains rivaroxaban, which selectively inhibits a key enzyme called factor Xa in the blood clotting. This reduces the formation of blood clots.

Should I take Rivarex 10 Tablet 10 with food?

You must take the medicine exactly as prescribed by your doctor.

What are the common side effects of Rivarex 10 Tablet 10?

Common side effects include bleeding complications, anaemia, nausea, peripheral swelling (oedema), dizziness and headache. Always consult your doctor if these persist.

Can I take Rivarex 10 Tablet 10 if I’m pregnant or breastfeeding?

You should use Rivarex 10 Tablet 10 with caution if you're pregnant due to potential risks. It's not recommended if you're breastfeeding as it's secreted in human milk.

What precautions should I take while using Rivarex 10 Tablet 10?

Avoid using this medicine if you have prosthetic heart valves, severe renal impairment or hepatic disease associated with coagulopathy. Always consult your doctor before use.

Can I stop taking Rivarex 10 Tablet 10 abruptly?

No. Do not discontinue without consulting your doctor first, as this may increase the risk of stroke. Always follow your doctor's instructions on discontinuation.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

PLOT NO : 1, NEW AHMEDABAD INDL. ESTATE, VILL. MORRAIYA, TAL, Sanand Rd, Changodar, Gujarat 382213

Country of origin: INDIA

References

Janssen Pharmaceuticals, Inc. (2021). HIGHLIGHTS OF PRESCRIBING INFORMATION. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/215859s000lbl.pdf
Bayer Inc. (2008). XARELTO (rivaroxaban tablets; rivaroxaban granules for oral suspension). In PRODUCT MONOGRAPH (1st ed.) [Anticoagulant; Oral]. https://www.bayer.com/sites/default/files/2020-11/xarelto-pm-en.pdf
Xarelto 2.5 mg film-coated tablets. (2022). [Book]. In SUMMARY OF PRODUCT CHARACTERISTICS. https://www.ema.europa.eu/en/documents/product-information/xarelto-epar-product-information_en.pdf
Singh, R., & Emmady, P. D. (2023, April 17). Rivaroxaban. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK557502/

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