Rolazin 500 Mg Tablet Er 10

Rolazin Tablet 10

Macleods Pharmaceuticals Pvt.ltd

Strip of 10 Units

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MRP ~~₹165.00~~

₹134.23

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Composition

Ranolazine (500 Mg)

Rolazin Tablet is primarily used for the management of chronic angina, a condition characterised by chest pain. This medicine is classified as an anti-anginal agent.

In addition to its main use, Rolazin Tablet can also be utilised along with other anti-anginal medications like beta-blockers, calcium channel blockers or nitrates. By increasing the ability of the heart to endure an imbalance between oxygen demand and supply, it helps in improving exercise tolerance and reducing the frequency of angina in patients with coronary artery disease.

Before starting this medicine, you should consult your doctor about your medical history and any ongoing medications. It's crucial to notify your doctor if you experience any side effects. For optimal results, continue taking Rolazin Tablet for the duration prescribed by your doctor.

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Managing chronic stable angina
Enhancing the heart's ability to tolerate imbalance between oxygen demand and supply
Improving exercise tolerance in individuals with coronary artery disease
Reducing the frequency of angina in patients with coronary artery disease

Swallow the tablet whole with a glass of water.
Do not break, chew or crush the tablet.
The medicine can be taken with or without food.
If you miss a dose, take it as soon as possible on the same day. If you don't remember until the next day, skip the missed dose and continue your regular dosing schedule.
Never take a double dose to make up for a missed one.
Always consult your doctor for personalized dosing instructions.

Rolazin Tablet is taken orally.

Dizziness
Headache
Constipation
Nausea and vomiting
Fatigue
Peripheral Edema: This refers to swelling in your limbs, such as hands, arms, feet, ankles or legs.

Managing the Side Effects:

Dizziness: If you're feeling dizzy after taking this medicine, it might be helpful to take it before bedtime.
Nausea and vomiting: Try taking Rolazin Tablet with food or milk to reduce these symptoms.

Rosalina Tablet contains Ranolazine, which works on your body in specific ways:

Inhibits Sodium Current: Ranolazine works on heart muscle cells by inhibiting the late inward sodium current. This action decreases the accumulation of sodium inside cells during ischemia, a condition where the heart muscle doesn't receive adequate blood supply.
Regulates Calcium: The reduced sodium accumulation prevents excess calcium from entering cells. Better regulation of sodium and calcium contributes to better relaxation of heart muscles and reduces stiffness in the left ventricle of the heart.
Reduces Heart's Workload: By enhancing myocardial relaxation (relaxation of heart muscles) and reducing left ventricular diastolic stiffness (stiffness in one part of the heart), ranolazine effectively reduces the workload on your heart and its oxygen consumption.

Pregnancy

If you are pregnant, it is advised to exercise caution while taking Rolazin Tablet. It's recommended to consult your doctor prior to taking this medicine.

Breastfeeding

Caution is advised if you're breastfeeding while taking Rolazin Tablet. Consult your doctor to understand the potential risks and benefits.

Alcohol

The interaction of Rolazin Tablet with alcohol is unknown. However, it's always a good idea to discuss your alcohol consumption habits with your doctor before starting this medicine.

Liver

This medicine is not recommended if you have severe liver problems. If you have mild to moderate liver impairment, take Rolazin Tablet with caution and discuss any concerns with your doctor beforehand.

Kidney

If you have kidney health issues, you should be cautious before using Rolazin Tablet. Always consult your doctor for advice tailored to your health condition.

Using Machines & Driving

Rolazin Tablet may cause dizziness which can affect your ability to drive or operate machinery. Do not drive or operate machinery if you feel dizzy after taking this medicine.

Allergy

Rolazin Tablet is contraindicated if you are allergic to ranolazine or any other components of the tablet. If you experience an allergic reaction, seek immediate medical help.

Children

Safety and efficacy of Rolazin Tablet in children under 18 years of age is not established. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Rolazin Tablet under medical supervision as they might be more prone to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Anti-Anginal Medications: Rolazin Tablet may interact with other anti-anginal drugs like beta-blockers, calcium channel blockers or nitrates, which could lead to lower blood pressure or slow heart rate.
CYP3A Inhibitors: Medicines like diltiazem, verapamil, erythromycin may increase the levels of ranolazine in your body, requiring a dosage adjustment of Rolazin Tablet.
Tricyclic Antidepressants: Combined use with these medicines increases the risk of low blood pressure and slow heart rate.
Digoxin: Consumption of Rolazin Tablet may raise digoxin levels in your body.

Drug-Food Interactions

Grapefruit Products: These can increase the amount of ranolazine in your body, potentially leading to increased side effects.

Drug-Disease Interactions

Severe Hepatic Impairment: Rolazin Tablet is not recommended for use in individuals with severe liver disease as it could exacerbate their condition.
Renal Impairment: Individuals with kidney problems may require dose adjustments of Rolazin Tablet.
Hypokalemia and Hypomagnesemia: Patients having low blood potassium or magnesium levels should use Rolazin Tablet cautiously due to increased risk of heart rhythm disorders.

Daily Dose

The daily dose of Rolazin Tablet should be taken as directed by your doctor. This dosage can vary based on individual factors like the severity of your condition and how you respond to the medicine. Always follow your doctor's prescribed dosage and never exceed it without consulting your doctor.

Over Dose

If you accidentally take more Rolazin Tablets than prescribed, you might feel dizzy or sick, or have a headache. If these symptoms persist or worsen, inform your doctor.

Missed Dose

In case you forget to take your regular dose of Rolazin Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your normal dosage schedule. Never increase the dosage without consulting your doctor.

Store your Rolazin Tablet in a cool and dry place.
The optimal storage temperature is between 20°C to 25°C.
Protect the tablets from moisture and direct sunlight.
Always keep this medicine out of reach of children.
Make sure to use the Rolazin Tablet before its expiry date.

If you're taking Rolazin Tablet for chronic stable angina, it's important to follow a heart-healthy diet low in saturated fats, trans fats, cholesterol, salt, and added sugars.
Regular physical activity is also beneficial. However, avoid strenuous exercise as it can put your heart under stress. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Anti-Anginal Agent
Therapeutic Category	Cardiovascular Medicine
Available Dosage Types	Extended-Release Tablet
Habit Forming	No
Ailment	Chronic Stable Angina

What is Rolazin Tablet used for?

Rolazin Tablet is primarily used to manage chronic angina, helping to balance the heart's oxygen demand and supply, thereby reducing chest pain.

Can I take Rolazin Tablet for acute chest pain attacks?

No, Rolazin Tablet is not meant for immediate relief of acute angina attacks. It's designed for long-term management of chronic angina.

How does Rolazin Tablet work in my body?

Rolazin Tablet works by improving energy metabolism in the heart muscle under conditions of inadequate blood supply, thereby reducing the heart's workload and oxygen consumption.

How should I take my Rolazin Tablets?

Rolazin Tablets should be swallowed whole without crushing or chewing. The exact instructions for taking it should be provided by your doctor.

Can I take Rolazin Tablets with other medications?

Yes, but only under the supervision of a doctor as certain drugs can interact with Rolazin Tablet causing undesirable effects.

What are some common side effects of taking Rolazin Tablets?

Common side effects may include dizziness, headache, constipation, nausea, and fatigue. If these persist or worsen, consult your doctor immediately.

Is it safe to take Rolazin Tablets during pregnancy?

The safety of using Rolazin Tablets during pregnancy is not established. Always consult your doctor if you are pregnant or planning to become pregnant.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

References

U.S. National Library of Medicine. (2024, April 1). Ranolazine. MedlinePlus. https://medlineplus.gov/druginfo/meds/a606015.html
U.S. Food and Drug Administration. (2010). Ranexa (ranolazine) Label. AccessData. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021526s012lbl.pdf
Reed, M., Kerndt, C. C., Gopal, S., Pellegrini, M. V., & Nicolas, D. (2024). Ranolazine. In StatPearls. StatPearls Publishing. https://pubmed.ncbi.nlm.nih.gov/29939605/

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