Rozutin Ap 20/150 Capsule 10

Knoll Healthcare Pvt. Ltd.

Strip of 10 Units

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MRP ~~₹108.9~~

₹54.34

₹10.89/Units

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Composition

Aspirin (150 Mg) + Rosuvastatin (20 Mg)

Rozutin Ap 20/150 Capsule is primarily used to manage cardiovascular health. It reduces the risk of blood clots, lowers cholesterol levels, and supports overall cardiovascular well-being. This medicine belongs to the group of medications known as antiplatelet agents and statins.

Besides its main use, this capsule also aids in reducing inflammation. It is particularly beneficial for patients who have experienced heart problems or strokes in the past, as it helps reduce the risk of such events reoccurring.

Take this capsule precisely as prescribed by your doctor. Swallow the capsule whole without crushing or chewing, ideally at the same time each day, to maintain consistent blood levels of the medication. Adherence to the prescribed course is essential to achieve the best results and minimise risks.

Rozutin Ap 20/150 Capsule is used for the following:

Management of high cholesterol levels
Reduction of inflammation in cardiovascular diseases
Prevention of blood clot formation
Secondary prevention in patients with atherosclerotic cardiovascular disease
Reducing the risk of future heart attacks, strokes and cardiovascular death in high-risk patients

Directions for Use of Rozutin Ap 20/150 Capsule 10

Follow these instructions while taking Rozutin Ap 20/150 Capsule:

Swallow the capsule whole with a glass of water.
Do not chew, crush, or open the capsule.
It's vital to take this medicine at the same time each day to ensure its effectiveness.
Do not stop taking this medicine without consulting your doctor first.

Rozutin Ap 20/150 Capsule is taken orally.

Side Effects of Rozutin Ap 20/150 Capsule 10

While taking Rozutin Ap 20/150 Capsule, you may experience some common side effects, such as:

Indigestion
Nausea
Diarrhoea
Headache
Bleeding

Managing the Side Effects:

Most side effects are temporary and generally harmless and resolve upon discontinuing the use of Rozutin Ap 20/150 Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of guidelines for managing common side effects:

Indigestion: Try taking Rozutin Ap 20/150 Capsule after meals to lessen this effect.
Diarrhoea: To manage this, consider taking the medicine with food.

Rozutin Ap 20/150 Capsule contains two active ingredients:

Aspirin (150 mg): This component works by permanently blocking an enzyme known as COX-1. As a result, it reduces the production of thromboxane A2, a substance that causes blood platelets to stick together, potentially forming clots. By doing so, aspirin helps prevent blood clot formation that could lead to heart attacks or strokes.
Rosuvastatin (20 mg): Rosuvastatin is part of a group of medicines called statins. It works by inhibiting HMG-CoA reductase, an enzyme critical to cholesterol production in the body. With less cholesterol being produced, and an increase in LDL receptors, rosuvastatin effectively lowers LDL-C, or "bad" cholesterol levels, total cholesterol and triglycerides while slightly increasing HDL-C or "good" cholesterol levels. This action helps slow down the progression of atherosclerosis (hardening and narrowing of arteries).

Pregnancy

If you are pregnant or planning to conceive, caution is advised while taking Rozutin Ap 20/150 Capsule. Consult your doctor to evaluate the potential risks and benefits before using this medication.

Breastfeeding

Breastfeeding mothers should discuss the use of Rozutin Ap 20/150 Capsule with their doctor, as some components may pass into breast milk and affect the infant.

Alcohol

Alcohol consumption can interfere with the effectiveness of Rozutin Ap 20/150 Capsule and increase the risk of side effects. Consult your doctor about any potential interactions and avoid alcohol while on this medication.

Liver

Patients with liver problems should use this medication with caution. Rosuvastatin, a component of the capsule, may affect liver function. It is recommended to consult your doctor, who may suggest liver function tests before starting or during treatment.

Kidney

If you have kidney issues, inform your doctor before starting Rozutin Ap 20/150 Capsule. Adjustments to dosage or additional monitoring may be required to avoid potential complications.

Using Machines & Driving

Some individuals may experience dizziness or drowsiness while taking Rozutin Ap 20/150 Capsule. Avoid driving or operating heavy machinery until you understand how this medication affects you.

Allergy

Rozutin Ap 20/150 Capsule should not be taken if you have known allergies to aspirin, and rosuvastatin, or any other ingredients in the formulation. Discuss alternative options with your doctor if you have a history of allergic reactions.

Children

This medicine is generally not recommended for individuals under 18 years of age. Only use under a doctor’s supervision if prescribed for younger patients.

Older Patients

Older adults may be more sensitive to the effects of Rozutin Ap 20/150 Capsule, particularly if they have existing liver or kidney conditions or are taking multiple medications. Close monitoring by a healthcare provider is advised.

Interactions of Rozutin Ap 20/150 Capsule 10

Drug-Drug Interactions

Rozutin Ap 20/150 Capsule interacts with the following medicines:

Non-Steroidal Anti-Inflammatory Drugs (NSAIDs): When taken together, NSAIDs like ibuprofen and naproxen may increase the risk of bleeding due to aspirin's antiplatelet effect.
Anticoagulants: Medicines such as warfarin and heparin used to prevent blood clots can have their effects intensified, increasing the risk of bleeding.
Fibrates and Niacin: These lipid-lowering medicines can increase the risk of muscle toxicity when used alongside rosuvastatin.

Drug-Food Interactions

Certain foods can interact with Rozutin Ap 20/150 Capsule:

Grapefruit Juice: It can increase rosuvastatin levels in the body, enhancing potential side effects.

Drug-Disease Interactions

Rozutin Ap 20/150 Capsule interacts with the following diseases:

Liver Disease: The medication should be used cautiously in patients with severe liver disease, as all three components are extensively metabolised in the liver.
Renal Impairment: Patients with severe kidney disease may require dose adjustments, particularly for rosuvastatin.
Gastrointestinal Disorders: Patients with a history of gastrointestinal ulcers or bleeding should exercise caution due to the antiplatelet effects of aspirin.

Daily Dose

The daily dose of Rozutin Ap 20/150 Capsule should be taken as advised by your doctor. The dosage could vary based on individual factors like the severity of the condition and how you respond to the medicine. Always adhere to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

If you accidentally take more than the recommended dose of Rozutin Ap 20/150 Capsule, you might feel nauseous or have a headache. If these symptoms persist or worsen, immediately inform your doctor.

Missed Dose

In case you forget to take your regular dose of this medicine, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your usual dosage schedule. Don't increase your dosage without discussing it with your doctor.

Store Rozutin Ap 20/150 Capsule in a cool place where the temperature is between 20°C and 25°C.
Keep the medicine in its original packaging to protect it from light and moisture.
Make sure this medication is stored out of the reach and sight of children.
Always check the expiration date on the packaging before use.

Since Rozutin Ap 20/150 Capsule is used for managing heart-related conditions, it's beneficial to adopt a diet low in saturated fats and cholesterol. This can help manage your cardiovascular health effectively.
Regular physical activity, such as brisk walking for at least 30 minutes each day, can also support heart health and complement the effects of this medication. Remember to consult your doctor before starting any new exercise programme.

Fact Box

Drug Category	Antiplatelet, Statin
Therapeutic Category	Cardiovascular
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Heart attack, Stroke, Peripheral arterial disease

What is Rozutin Ap 20/150 Capsule used for?

Rozutin Ap 20/150 Capsule is primarily used to reduce the risk of future cardiovascular events, such as heart attacks and strokes, in patients with established atherosclerotic cardiovascular disease (ASCVD).

How does Rozutin Ap 20/150 Capsule work?

This capsule combines aspirin and rosuvastatin to reduce the risk of blood clots, lower cholesterol, and manage inflammation, collectively supporting cardiovascular health and reducing recurrent cardiovascular events.

How should I take Rozutin Ap 20/150 Capsule?

Take this capsule as directed by your doctor. Do not crush or chew it, and try to take it at the same time each day to ensure consistency.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. If it is close to your next scheduled dose, skip the missed dose and continue as normal. Avoid taking a double dose to make up for a missed one.

Can I use Rozutin Ap 20/150 Capsule during pregnancy or breastfeeding?

Consult your doctor before using this medicine during pregnancy or while breastfeeding to understand the potential risks involved.

What are the possible side effects of Rozutin Ap 20/150 Capsule?

Common side effects include gastrointestinal discomfort, nausea, headache, and mild bleeding. Severe side effects may include intracranial bleeding or thrombotic thrombocytopenic purpura (TTP). If you experience any unusual symptoms, seek medical attention immediately.

Can I take other medicines while using Rozutin Ap 20/150 Capsule?

Inform your doctor about all medications you are taking before starting this medicine due to possible medication interactions.

Last Updated On 03 Mar. 2025 | 2:25PM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

M17, Pharma Tower,, Phase-1, Badli Industrial Area,, Badli, Delhi, 110042

Country of origin: INDIA

References

AstraZeneca. (2003). CRESTOR. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021366s016lbl.pdf
New Haven Pharmaceuticals. (2015). HIGHLIGHTS OF PRESCRIBING INFORMATION [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/200671s000lbl.pdf
European Medicines Agency. (n.d.). DuoPlavin 75 mg/75 mg and 75 mg/100 mg Film-Coated capsules. In Summary of Product Characteristics. https://www.ema.europa.eu/en/documents/product-information/duoplavin-epar-product-information_en.pdf
Rosuvastatin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a603033.html
Aspirin: MedlinePlus drug information. (n.d.). https://medlineplus.gov/druginfo/meds/a682878.html

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