Selgin Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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MRP ~~₹94~~

₹75.2

₹9.4/Units

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Composition

Selegiline (5 Mg)

Selgin Tablet is primarily used in the management of Parkinson's disease. This medicine is part of a group known as monoamine oxidase-B (MAO-B) inhibitors.

This medicine can also be employed to help control excessive movements that are often associated with Parkinson's disease. By increasing the dopamine levels in the brain, this medicine allows for better control of these symptoms.

You should take this medicine as directed by your doctor. It's important to inform your doctor of any pre-existing conditions or ongoing medications before you start taking this medicine. Should you experience any side effects, notify your doctor immediately. For best results, continue taking the medicine for the duration prescribed by your doctor.

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Selgin Tablet is used for the following:

Management of Parkinson's disease: This medicine is used to manage the symptoms and slow the progression of Parkinson's disease, a neurological disorder resulting in difficulty with movement and coordination.
Reduction of excessive movements: By increasing dopamine levels in the brain, Selgin Tablet helps manage excessive, uncontrollable movements often seen in Parkinson's disease patients.

Swallow the tablet whole with a glass of water. Avoid crushing or chewing it.
Follow your doctor's instructions on when and how often to take this medication. Do not exceed the prescribed dose.

Selgin Tablet is taken orally.

Selgin Tablet may cause the following side effects:

Nausea
Vomiting
Dizziness
Headache
Confusion: This medicine may cause a state of confusion or difficulty in understanding.
Agitation: You might feel disturbed or excited after taking Selgin Tablet.
Sleep disturbances: It might affect your sleep pattern causing insomnia or abnormal sleep.
Orthostatic hypotension: This refers to a sudden drop in blood pressure when you stand up from a sitting or lying position.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Selgin Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea: Try taking Selgin Tablet with food to lessen this effect.
Orthostatic hypotension: Consider taking this medicine at night if it causes a sudden drop in blood pressure upon standing up.

Selgin Tablet contains Selegiline (5 mg). This medicine works in the following ways:

Selective MAO-B Inhibition: Selegiline selectively and irreversibly inhibits an enzyme in your brain called monoamine oxidase type B (MAO-B). This enzyme is responsible for breaking down dopamine and other neurotransmitters in the brain.
Increase in Dopamine Levels: By blocking the activity of MAO-B, Selegiline increases the availability of dopamine in the brain. More available dopamine leads to improved motor functions and a decrease in the symptoms of Parkinson's disease.

Pregnancy

Caution is advised while taking Selgin Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's wise to discuss this with your doctor before starting on Selgin Tablet.

Alcohol

While on Selgin Tablet, it's recommended to limit or avoid alcohol intake. Excessive alcohol can exacerbate some of the side effects of this medicine.

Liver

Patients with liver problems should discuss their medical history with the doctor before starting Selgin Tablet. This medicine may affect liver function.

Kidney

Caution is advised before using Selgin Tablet if you have a history of kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Selgin Tablet might cause dizziness or sleepiness, which could affect your ability to drive or operate machines. If you experience these symptoms, be cautious while driving or using heavy machinery.

Allergy

If you are allergic to Selegiline or any other ingredients in Selgin Tablet, it is important to inform your doctor. An allergic reaction could cause severe side effects.

Children

Selgin Tablet should be given with caution to children under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Selgin Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Selgin Tablet interacts with the following medicines:

Opioids: When combined with Selgin Tablet, medicines like morphine and codeine may potentially increase the risk of serotonin syndrome, a serious condition characterised by symptoms like agitation and fever.
Selective serotonin reuptake inhibitors (SSRIs): Medicines such as fluoxetine or sertraline, when taken alongside Selgin Tablet, can significantly increase serotonin levels leading to serotonin syndrome.
Tricyclic antidepressants: Antidepressants like amitriptyline and imipramine may interact with Selgin Tablet, potentially exacerbating the risk of serotonin syndrome.
Cough suppressants: Products containing dextromethorphan can interact with Selgin Tablet, leading to increased levels of dextromethorphan in the body.

Drug-Food Interactions

Certain foods may interact with Selgin Tablet. For instance:

Aged cheeses and cured meats: Foods high in tyramine can interact with Selgin Tablet, leading to a potential increase in blood pressure.

Drug-Disease Interactions

Selgin Tablet interacts with the following diseases:

Peptic Ulcers: The medication may aggravate symptoms in patients suffering from peptic ulcers.
Cardiovascular disease: Patients with cardiovascular disease should use Selgin Tablet cautiously as it may have adverse effects on their condition.
Psychiatric disorders: Those with psychiatric disorders should be cautious when using Selgin Tablet as it might exacerbate their symptoms.

Daily Dose

The daily dose of Selgin Tablet must be taken as directed by your doctor. This may vary depending on factors like the severity of your condition and how you respond to the medicine. Never change the dosage without consulting your doctor.

Over Dose

If you accidentally take more than the prescribed dose of Selgin Tablet, you might experience symptoms like severe headache, sudden high blood pressure, confusion, and agitation. In such a case, inform your doctor about it.

Missed Dose

In case you forget to take a dose of Selgin Tablet, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your usual dosage schedule. Always consult your doctor before making any changes to the dosage.

Store Selgin Tablet in a cool, dry place where the temperature stays below 25°C.
Keep it away from direct light and moisture.
Make sure to keep it out of reach and sight of children.
Always check the expiry date on the packet and don't use it after this date.

Since Selgin Tablet is used to manage Parkinson's disease, engage in regular light exercise, like walking or yoga, as it can help improve muscle strength and balance.
Include foods rich in antioxidants such as berries, nuts, and leafy green vegetables in your diet. These foods are known to support brain health. Always consult your doctor before making significant dietary changes.

Fact Box

Drug Category	MAO-B Inhibitor
Therapeutic Category	Antiparkinsonian
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Parkinson's Disease

What is Selgin Tablet used for?

Selgin Tablet is primarily used to manage Parkinson's disease, helping to control body movements by increasing dopamine levels in the brain.

How does Selgin Tablet work?

Selgin Tablet contains Selegiline, which blocks an enzyme responsible for breaking down dopamine, thereby increasing dopamine availability in the brain.

Are there any side effects of taking Selgin Tablet?

Yes, some common side effects are nausea, headache, dizziness, and sleep disturbances. Severe or persistent side effects should be reported to your doctor immediately.

Is Selgin Tablet safe for everyone?

No. People allergic to Selegiline or any other ingredients in the medicine should avoid it. Also, patients with peptic ulcers, cardiovascular disease or psychiatric disorders should use it with caution.

Can I take Selgin Tablet with other medications?

Some medicines can interact with Selgin Tablet. Always consult your doctor before starting any new medication while taking Selgin Tablet.

How should I store my Selgin Tablet?

Store them in a cool, dry place away from direct sunlight and moisture. Keep them out of reach from children and pets.

What if I accidentally take an extra dose of Selgin Tablet?

If you overdose on Selgin Tablet, seek immediate medical attention. Symptoms may include severe headache, high blood pressure, confusion and seizures.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

U.S. National Library of Medicine. (2020). Selegiline. MedlinePlus. Retrieved 13 October 2024, from
https://medlineplus.gov/druginfo/meds/a697046.html.
U.S. Food and Drug Administration. (2006). FDA Label for Selegiline. Accessdata.fda.gov. Retrieved 13 October 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021479lbl.pdf.
Moore, J. J., & Saadabadi, A. (2023). Selegiline. In StatPearls [Internet]. StatPearls Publishing. Retrieved 13 October 2024, from
https://www.ncbi.nlm.nih.gov/books/NBK526094/
Chrisp, P., Mammen, G. J., & Sorkin, E. M. (1991). Selegiline. A review of its pharmacology, symptomatic benefits and protective potential in Parkinson’s disease. Drugs & Aging, 1(3), 228–248. Retrieved 13 October 2024, from
https://pubmed.ncbi.nlm.nih.gov/1794016/

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