Sgltd M 10/1000 Tablet 10

Mankind Pharmaceuticals Ltd.

Strip of 10 Units

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MRP ~~₹139.2~~

₹111.36

₹13.92/Units

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Composition

Dapagliflozin (10 Mg) + Metformin (1000 Mg)

Sgltd-M 10/1000 Tablet is used to manage type 2 diabetes in adults. It's a combination medicine that belongs to the class of sodium-glucose co-transporter 2 (SGLT2) inhibitors and biguanides.

Besides controlling diabetes, this medicine also reduces the risk of hospitalization due to heart failure in adults who already have heart disease or multiple risk factors. It is important to note that this medication isn't for type 1 diabetes.

Before starting this medicine, you should consult your doctor, who will guide you on the right dosage and frequency. Inform your doctor about any existing health conditions or ongoing medications. If you notice any side effects, report them to your doctor immediately. Remember, to achieve the best results, continue taking the medicine for the entire duration prescribed by your doctor.

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Sgltd-M 10/1000 Tablet is used for the following:

Managing blood sugar levels in adults with type 2 diabetes mellitus.
Assisting with diet and exercise to improve glycemic control in adults with type 2 diabetes.
Reducing the risk of hospitalisation due to heart failure in adults with type 2 diabetes and established cardiovascular disease or multiple cardiovascular risk factors.

Directions for Use of Sgltd M 10/1000 Tablet 10

When taking Sgltd-M 10/1000 Tablet, it's recommended you adhere to the following guidelines:

Swallow the tablet whole with water.
Avoid cutting, crushing, or chewing the tablet.
Do not exceed the prescribed dose without discussing it with your doctor.
Consult your doctor before discontinuing this medication.

Sgltd-M 10/1000 Tablet is taken orally.

Side Effects of Sgltd M 10/1000 Tablet 10

Sgltd-M 10/1000 Tablet may have the following common side effects:

Female genital mycotic infections: This is a type of fungal infection that affects the female genital area.
Nasopharyngitis
Urinary tract infections: These are infections that affect any part of your urinary system, which includes your kidneys, bladder, ureters and urethra.
Diarrhoea
Headache
Nausea
Influenza
Back pain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Sgltd-M 10/1000 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Sgltd-M 10/1000 Tablet with food or milk.
Nausea: Consider taking this medicine after meals to lessen this effect.

Sgltd-M 10/1000 Tablet contains two active ingredients that work together to manage type 2 diabetes:

Dapagliflozin (10 mg): This ingredient is an SGLT2 inhibitor. It reduces the amount of sugar reabsorbed by the kidneys and increases the amount of sugar excreted in the urine. By doing so, it helps lower the blood sugar levels in your body.
Metformin (1000 mg): Metformin works by decreasing the production of sugar in the liver and reducing the absorption of sugar in the intestines. It also improves the body's response to insulin, a hormone that controls the amount of sugar in your blood. This action helps to lower your blood sugar levels.

Pregnancy

It's crucial to exercise caution while taking Sgltd-M 10/1000 Tablet if you're pregnant. This medicine should only be used if the potential benefit outweighs the risk to the foetus. Always consult your doctor before starting on this medication.

Breastfeeding

Sgltd-M 10/1000 Tablet is not recommended during breastfeeding. The decision to discontinue either breastfeeding or the medication should be made considering the importance of the medicine to the mother.

Alcohol

Excessive alcohol consumption while on Sgltd-M 10/1000 Tablet can increase your risk of lactic acidosis, a potential side effect of metformin. It is advised that you moderate your intake and discuss any concerns with your doctor.

Liver

If you have liver issues, be cautious when taking Sgltd-M 10/1000 Tablet. It's best to discuss your liver health with your doctor before starting this medicine, especially as liver impairment may affect its function.

Kidney

Since Sgltd-M 10/1000 Tablet is contraindicated in patients with moderate to severe renal impairment, it's important to consult your doctor if you have any kidney problems before starting this medication.

Using Machines & Driving

No specific precautions are required while using machines or driving when taking Sgltd-M 10/1000 Tablet. However, if you experience side effects that might affect your ability to concentrate or react, it's best to avoid such activities until you're sure how the medicine affects you.

Allergy

If you have a history of hypersensitivity reactions to dapagliflozin, metformin, or any other ingredients in Sgltd-M 10/1000 Tablet, avoid taking this medicine. Make sure your doctor is aware of any allergies you might have.

Children

Sgltd-M 10/1000 Tablet is not recommended for use in children as its safety and effectiveness have not yet been established in this age group.

Older Patients

Older patients taking Sgltd-M 10/1000 Tablet may be more vulnerable to certain side effects, particularly those related to reduced intravascular volume. It's advised that renal function is monitored more frequently in these patients. As always, consult your doctor before starting any new medication regimen.

Interactions of Sgltd M 10/1000 Tablet 10

Drug-Drug Interactions

Sgltd-M 10/1000 Tablet interacts with the following medicines:

Carbonic anhydrase inhibitors: Medications such as acetazolamide or dorzolamide can increase the risk of lactic acidosis, a serious side effect associated with metformin.
Medicines reducing metformin clearance: Medicines like cimetidine may lead to an increase in metformin levels; hence, caution is advised.
Diuretics: Medicines like furosemide or hydrochlorothiazide may enhance the risk of low blood pressure (hypotension) when used alongside dapagliflozin.

Drug-Food Interactions

Drug-Disease Interactions

Sgltd-M 10/1000 Tablet interacts with the following diseases:

Kidney Disease: This medicine should not be used if you have moderate to severe renal impairment or end-stage renal disease. It's vital to monitor kidney function regularly while on this medication.
Liver Disease: Use of Sgltd-M 10/1000 Tablet is not advised for those with liver disease due to the potential for further deterioration of liver function.
Metabolic Acidosis: People suffering from metabolic acidosis, including diabetic ketoacidosis, should avoid using this medication as it might worsen their condition.

Daily Dose

The daily dose of Sgltd-M 10/1000 Tablet should be taken as directed by your doctor. The dosage may vary based on factors such as your condition's severity and how well you respond to the medication. Always follow the prescribed dosage and never exceed it without consulting your doctor. For further details regarding dosage, refer to the package insert.

Over Dose

Overdosing on Sgltd-M 10/1000 Tablet could lead to symptoms similar to the side effects mentioned in the package insert. If you accidentally take more than the prescribed dose, contact your doctor. They will provide you with further instructions based on your symptoms.

Missed Dose

If you forget to take Sgltd-M 10/1000 Tablet at the scheduled time, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Remember, never adjust your dosage without consulting your doctor.

Store your Sgltd-M 10/1000 Tablet in a cool, dry place where the temperature stays between 15°C and 30°C.
Keep it away from direct light and moisture.
Ensure it's out of reach and sight of children.
Always remember to use this medicine before the expiry date marked on the pack.

Since Sgltd-M 10/1000 Tablet is used to manage type 2 diabetes, try to maintain a balanced diet low in sugar and high in fibre.
Regular physical activity can also help control your blood sugar levels, so aim for at least 150 minutes of moderate-intensity exercise each week.

Fact Box

Drug Category	SGLT2 Inhibitor, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus, Cardiovascular Risk Management

What is Sgltd-M 10/1000 Tablet used for?

Sgltd-M 10/1000 Tablet is used to manage type 2 diabetes mellitus in adults, as part of a healthy diet and exercise routine.

How does Sgltd-M 10/1000 Tablet work?

It contains two active ingredients that lower blood sugar levels. Dapagliflozin reduces the reabsorption of glucose, while metformin decreases glucose production and improves insulin sensitivity.

Can I take Sgltd-M 10/1000 Tablet if I have kidney problems?

If you have moderate to severe renal impairment, end-stage renal disease, or are on dialysis, you should not take this medicine. Always consult your doctor.

Are there any side effects of Sgltd-M 10/1000 Tablet?

Yes, common side effects include genital mycotic infections, nasopharyngitis, urinary tract infections, diarrhoea, headaches, nausea, influenza and back pain.

Can I take Sgltd-M 10/1000 Tablet if I'm pregnant or breastfeeding?

There aren't enough studies on its effects during pregnancy or breastfeeding. Consult your doctor to weigh potential benefits against possible risks.

What precautions should I take when using Sgltd-M 10/1000 Tablet?

Monitor renal function, watch for symptoms of lactic acidosis and hypotension, and be aware of the increased risk of genital mycotic infections and vitamin B12 deficiency.

How should I store my Sgltd-M 10/1000 Tablets?

Store at temperatures between 20°C to 25°C (68°F to 77°F), with permitted excursions between 15°C and 30°C (59°F and 86°F).

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

208, Okhla Industrial Estate, Phase-III, New Delhi South Delhi DL 110020 IN

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2014). FDA Label - Dapagliflozin and Metformin HCL. https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/202293s003lbl.pdf. Accessed 1 April 2024.
U.S. Food and Drug Administration. (2006). FDA Label - Metformin HCL. https://www.accessdata.fda.gov/drugsatfda_docs/label/2006/021748s002lbl.pdf. Accessed 1 April 2024.
DailyMed. (n.d.). Dapagliflozin and Metformin HCL - Dapagliflozin and Metformin hydrochloride tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=72ad22ae-efe6-4cd6-a302-98aaee423d69. Accessed 1 April 2024.
DailyMed. (n.d.). Metformin HCL - Metformin hydrochloride tablet, film coated. https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=1200ea71-8a9e-4e49-bb77-7d9fe0d84ae7. Accessed 1 April 2024.
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 9887712, Dapagliflozin. Retrieved November 17, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Dapagliflozin.

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Disclaimer

We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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