Sgltr Tablet 10

Mankind Pharmaceuticals Ltd.

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Composition

Remogliflozin Etabonate (100 Mg)

SGLTR Tablet is specifically designed to manage type 2 diabetes mellitus in adults. It's part of a group of medicines known as sodium-glucose co-transporter-2 (SGLT2) inhibitors.

In addition to its primary use, this medicine plays a vital role in reducing blood sugar levels, thereby improving glycemic control. This medicine can be used on its own or in combination with other antidiabetic medications, such as metformin, when diet and exercise alone aren't sufficient to maintain optimal glycemic control.

It is essential to take this medicine as directed by your doctor. Inform your doctor about any pre-existing conditions or ongoing medications before you start taking this tablet. If you experience any side effects while on this medication, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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SGLTR Tablet is used for the following:

Managing type 2 diabetes mellitus in adults: This medicine helps control your blood sugar levels.
Improving glycemic control: This means SGLTR Tablet helps reduce your overall blood sugar levels.
Use as an adjunct to diet and exercise: When diet and physical activity alone don't manage your blood sugar levels effectively, SGLTR Tablet can be added to your routine.
Combination therapy with other antidiabetic medicines: If other diabetes medicines like metformin aren't effective enough on their own, doctors might prescribe SGLTR Tablet along with them.

Here's how you should take SGLTR Tablet:

Swallow the tablet whole with a glass of water.
You can take it with or without food, whichever suits you better.
Make sure you drink plenty of fluids throughout the day.
Never chew or break the tablet.

SGLTR Tablet is taken orally.

SGLTR Tablet may have the following common side effects:

Genital mycotic infections: These are fungal infections that can occur in the genital area.
Urinary tract infections
Increased urination
Thirst
Constipation
Nausea
Dizziness
Back pain

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of SGLTR Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Increased urination: Try to take SGLTR Tablet in the morning to manage this.
Nausea: If you feel nauseous after taking this medicine, consider taking it with a meal to lessen this effect.

SGLTR Tablet contains Remogliflozin Etabonate (100 Mg), which works on the body as follows:

Inhibits SGLT2: Remogliflozin Etabonate blocks a protein called SGLT2 in your kidneys. This protein is responsible for the reabsorption of glucose, a type of sugar, in your body.
Reduces Blood Sugar: By blocking the activity of SGLT2, Remogliflozin Etabonate effectively reduces the reabsorption of filtered glucose and increases urinary glucose excretion, lowering blood sugar levels. This action is independent of insulin and complements other antidiabetic medications that work through different pathways.

Pregnancy

SGLTR Tablet is contraindicated in pregnancy. If you are pregnant or planning to conceive, it's crucial to discuss this with your doctor before starting this medicine.

Breastfeeding

SGLTR Tablet is contraindicated for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

Caution is advised while consuming alcohol during the course of SGLTR Tablet. Excessive alcohol intake may lead to dehydration and might interfere with the medicine's efficacy.

Liver

Caution is advised while taking SGLTR Tablet if you have liver problems. Before starting this medicine, discuss them with your doctor, as it might affect liver function.

Kidney

SGLTR Tablet is contraindicated in patients with severe kidney impairment or those undergoing dialysis. It's important to discuss any kidney health issues with your doctor before taking this medication.

Using Machines & Driving

Whenever taking a new medication, be cautious about driving or operating machinery until you know how it affects you. SGLTR Tablet may cause dizziness, so it's best to understand how you react to it before engaging in such activities.

Allergy

SGLTR Tablet should not be taken if you have known hypersensitivity to Remogliflozin Etabonate or any other ingredients in the tablet. If you've previously had allergic reactions to similar medications, consult your doctor for advice.

Children

Caution is advised while giving SGLTR Tablet to those under 18. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take SGLTR Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

SGLTR Tablet interacts with the following medicines:

Diuretics: Can increase the risk of dehydration and low blood pressure. Specific medicines include furosemide and hydrochlorothiazide.
Insulin and Insulin Secretagogues: There's a chance of low blood sugar, so you might need to adjust your dose. This includes medicines like insulin glargine and glipizide.
Lithium: SGLTR Tablet might increase lithium levels in your blood. Regular monitoring is recommended if you are on lithium therapy.
Cardiac glycosides: Medicines like digoxin may interact with SGLTR Tablet, leading to high digoxin levels in the body. Monitoring digoxin levels is advised.

Drug-Food Interactions

Drug-Disease Interactions

SGLTR Tablet interacts with the following diseases:

Genital Mycotic Infections: If you have a history of these infections, you should use SGLTR Tablet cautiously, as it could increase your risk of getting another infection.
Urinary Tract Infections: Individuals with urinary tract infections should use this medicine carefully as it may lead to recurrent infections.
Renal Impairment: If you have kidney disease, your dose may need adjusting because this medicine can decrease kidney function slightly.

Daily Dose

Your doctor will prescribe the daily dosage of SGLTR Tablet you need to take. This may vary based on factors like how severe your condition is and how your body responds to the medicine. It's crucial to follow your doctor's instructions. Don't increase the dose without consulting your doctor.

Over Dose

Overdosing on SGLTR Tablets can lead to side effects like increased urination, thirst, nausea, and dizziness. If you accidentally take more than your prescribed dose, don't panic, but inform your doctor about it.

Missed Dose

Take it as soon as you remember. If it's nearly time for your next dose, don't worry about the missed one and simply continue with your regular dosing schedule. But remember, never adjust your dose without talking to your doctor first.

Store your SGLTR Tablet at room temperature, specifically between 15-30°C.
Keep it in a tightly closed container to protect it from moisture.
Always shield it from direct sunlight.
Ensure it's kept out of the reach of children.
Never forget to use the tablet before its expiry date.

Include regular exercise in your routine. This can help manage your blood sugar levels, making SGLTR Tablet more effective for managing type 2 diabetes.
Adopt a balanced diet low in sugars and refined carbohydrates. Such foods can spike your blood sugar levels, undermining the effectiveness of SGLTR Tablet.

Fact Box

Drug Category	SGLT2 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes Mellitus

What illness does SGLTR Tablet manage?

SGLTR Tablet is used to manage type 2 diabetes in adults by decreasing blood sugar levels.

How does SGLTR Tablet work?

It inhibits a protein in the kidneys that absorbs glucose, resulting in more glucose being passed out through urine, reducing blood sugar levels.

Can I use other diabetes medicines with SGLTR Tablet?

Yes, you can take it alongside other diabetes medicines like metformin if your blood sugar level isn't adequately controlled by diet and exercise alone.

Are there any side effects of SGLTR Tablet?

Some common side effects include yeast infections, urinary tract infections, increased urination, thirst, constipation, nausea, dizziness, and back pain.

What precautions should I take while using SGLTR Tablet?

Ensure adequate fluid intake to prevent dehydration, and inform your doctor if you have a history of genital yeast infections or urinary tract infections.

Can I take SGLTR Tablet if I am pregnant or breastfeeding?

The safety of this medicine during pregnancy and lactation hasn't been established. Please consult your doctor before using it.

What should I do if I miss a dose of SGLTR Tablet?

Take it as soon as you remember unless it's almost time for your next dose. Never double up on doses to compensate for a missed one.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

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Manufacturer details

208, Okhla Industrial Estate, Phase-III, New Delhi South Delhi DL 110020 IN

Country of origin: INDIA

References

Mohan, V., Mithal, A., Joshi, S. R., Aravind, S., & Chowdhury, S. (2020). Remogliflozin Etabonate in the treatment of type 2 diabetes: Design, development, and place in Therapy. Drug Design, Development and Therapy, 14, 2487-2501. https://doi.org/10.2147/dddt.s221093
Remogliflozin etabonate. (2024, October 3). DrugBank Online | Database for Drug and Drug Target Info. https://go.drugbank.com/drugs/DB12935
PubChem. (n.d.). Remogliflozin etabonate. National Center for Biotechnology Information. https://pubchem.ncbi.nlm.nih.gov/compound/Remogliflozin-etabonate
Shimizu, K., Fujikura, H., Fushimi, N., Nishimura, T., Tatani, K., Katsuno, K., Fujimori, Y., Watanabe, S., Hiratochi, M., Nakabayashi, T., Kamada, N., Arakawa, K., Hikawa, H., Azumaya, I., & Isaji, M. (2021). Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor. Bioorganic & Medicinal Chemistry, 34, 116033. https://www.sciencedirect.com/science/article/abs/pii/S0968089621000419

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