Siloford 8mg Tablet 10

Roussel Laboratories Pvt Ltd

Strip of 10 Units

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MRP ~~₹382~~

₹190.62

₹38.20/Units

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Composition

Silodosin (8 Mg)

Strength:

8 MG 4 MG

Siloford 8mg Tablet 10 is primarily used to manage symptoms of benign prostatic hyperplasia (BPH) in adult men. It belongs to a group of medicines known as alpha-adrenergic antagonists.

In addition to its main use, it significantly improves urinary symptoms associated with BPH, such as difficulty starting urination, a weak urine stream, frequent or urgent need to urinate, increased night-time urination, and the feeling of incomplete bladder emptying. However, it does not reduce the size of the prostate.

Always consult your doctor about any pre-existing conditions or ongoing medications before starting this treatment. If you experience any side effects, notify your doctor immediately. Continue taking the medicine for the duration prescribed by your doctor to achieve the best results.

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Siloford 8mg Tablet 10 is used for the following health conditions:

Management of benign prostatic hyperplasia (BPH) in adult men. This is a noncancerous enlargement of the prostate gland, which can cause uncomfortable urinary symptoms
Handling the difficulty in starting urination, which may be caused by BPH
Reducing the weak urine stream often experienced by men with BPH
Controlling frequent or urgent need to urinate, another symptom associated with BPH
Addressing the feeling of incomplete bladder emptying often experienced by those facing BPH

Directions for Use of Siloford 8mg Tablet 10

Swallow the medicine whole with a glass of water.
Do not crush or chew it.
It's crucial not to stop taking this medication without consulting your doctor first.

Siloford 8mg Tablet 10 is taken orally.

The common side effects of Siloford 8mg Tablet 10 might include:

Dizziness
Diarrhoea
Headache
Nasal congestion
Orthostatic hypotension: This refers to a drop in blood pressure when you move from sitting or lying down to standing up.
Retrograde ejaculation: This is an occurrence where there is an orgasm with reduced or no semen.
Nasopharyngitis: This is the medical term for the common cold.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Siloford 8mg Tablet 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of suggestions for managing common side effects:

Dizziness: Consider taking Siloford 8mg Tablet 10 at bedtime to lessen the impact of dizziness during your daily activities.
Diarrhoea: Try taking Siloford 8mg Tablet 10 with food to help mitigate this effect.

Siloford 8mg Tablet 10 contains silodosin (8 mg), which works on the body as follows:

Alpha-1 adrenoreceptor antagonist: Silodosin selectively binds to alpha-1A adrenergic receptors located in various parts of the urinary system, including the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.
Relaxes smooth muscles: By binding to these receptors, silodosin induces relaxation in these smooth muscles. This decreases resistance to urine flow and improves BPH symptoms.

Pregnancy

Breastfeeding

Alcohol

Moderation is advised when consuming alcohol while taking Siloford 8mg Tablet 10. Excessive drinking could heighten the risk of side effects like dizziness or fainting. It's best to discuss your alcohol consumption with your doctor.

Liver

If you have moderate liver problems, exercise caution when using Siloford 8mg Tablet 10. This medication is not recommended for those with severe liver impairment. Before starting the medicine, be sure to discuss any liver issues with your doctor.

Kidney

For individuals with severe kidney issues, caution is essential when taking Siloford 8mg Tablet 10. Consult your doctor to determine if this medication is appropriate for you.

Using Machines & Driving

Since Siloford 8mg Tablet 10 can cause side effects like dizziness and fainting, it is advisable to avoid risky activities, such as driving or operating heavy machinery, until you are aware of how the medication affects you.

Allergy

Do not take Siloford 8mg Tablet 10 if you're allergic to silodosin or any of its ingredients. If you've had an allergic reaction to similar medications in the past, inform your doctor before starting this medication.

Children

Siloford 8mg Tablet 10 should not be given to children under 18 years of age, as its safety and efficacy in this population has not been established.

Older Patients

Elderly male patients can take Siloford 8mg Tablet 10 under medical supervision, as they may be more susceptible to its side effects. Your doctor will provide guidance based on your health status.

Drug-Drug Interactions

Siloford 8mg Tablet 10 interacts with the following medicines:

CYP3A4 inhibitors: Medicines such as ketoconazole, clarithromycin, itraconazole, and ritonavir can significantly increase exposure to silodosin, potentially enhancing its effects and side effects.
Alpha-blockers: Using Siloford 8mg Tablet 10 with other alpha-blockers, like alfuzosin and doxazosin, may amplify the blood pressure-lowering effects.
Antihypertensive agents: Concurrent use with antihypertensive medications, such as captopril and lisinopril, may enhance hypotensive effects.
Phosphodiesterase type 5 (PDE5) inhibitors: Combining PDE5 inhibitors, like sildenafil and vardenafil, with Siloford 8mg Tablet 10 can increase the risk of symptomatic hypotension.

Drug-Food Interactions

Siloford 8mg Tablet 10 interacts with the following foods:

Grapefruit and grapefruit juice: These foods should be avoided during treatment with Siloford 8mg Tablet 10 as they can increase medicine exposure.

Drug-Disease Interactions

Siloford 8mg Tablet 10 interacts with the following diseases:

Renal impairment: Patients with severe renal impairment should exercise caution when taking Siloford 8mg Tablet 10, as it could worsen their condition.
Hepatic impairment: For those suffering from moderate to severe hepatic impairment, this medication needs to be used cautiously.
Hypotension: If you have a history of low blood pressure, the use of this medication could possibly further lower your blood pressure.

Daily Dose

Following your doctor's prescription is essential when taking Siloford 8mg Tablet 10. Your dosage may be adjusted based on factors such as your response to the medicine and the severity of your condition. Always stick to the prescribed dosage and avoid exceeding it without consulting your doctor.

Over Dose

An overdose of Siloford 8mg Tablet 10 may cause intensified side effects such as dizziness or a sudden drop in blood pressure when standing up. If you suspect an overdose, contact your doctor immediately to discuss your symptoms and seek appropriate advice.

Missed Dose

If you miss a dose of Siloford 8mg Tablet 10, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Do not store above 30°C.
Store in the original package in order to protect from light and moisture.
Keep out of reach of children.

If you're taking Siloford 8mg Tablet 10 to manage benign prostatic hyperplasia (BPH), try to limit your intake of caffeine and alcohol. These can stimulate your bladder and increase the frequency of urination.
Regular physical activity can help reduce symptoms of BPH. Try to incorporate exercises like walking or swimming into your daily routine. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Alpha-1 Adrenoreceptor Antagonist
Therapeutic Category	Urological Agent
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Benign Prostatic Hyperplasia, Urinary Symptoms

What is Siloford 8mg Tablet 10 used for?

Siloford 8mg Tablet 10 is used to manage the symptoms of benign prostatic hyperplasia (BPH), a noncancerous enlargement of the prostate gland in adult men.

How does Siloford 8mg Tablet 10 work?

Siloford 8mg Tablet 10 contains silodosin, which relaxes the muscles in the prostate and bladder neck, improving urine flow and reducing BPH symptoms.

Can I crush or break Siloford 8mg Tablet 10?

No, this tablet should be swallowed whole. If you have difficulty swallowing it, consult your doctor for appropriate alternatives.

What are some common side effects of Siloford 8mg Tablet 10?

Common side effects include retrograde ejaculation, dizziness, diarrhoea, low blood pressure upon standing, headaches, nasal congestion, and common cold symptoms. Consult your doctor if they persist or worsen.

Are there any situations where I should not take Siloford 8mg Tablet 10?

Do not take Siloford 8mg Tablet 10 if you are allergic to silodosin or any other ingredients in it. Avoid using it if you are taking strong CYP3A4 inhibitors, such as ketoconazole.

Should I inform my ophthalmologist about my use of Siloford 8mg Tablet 10?

Yes, if you are planning to undergo cataract or glaucoma surgery, inform your ophthalmologist, as Siloford 8mg Tablet 10 can cause complications during surgery.

Can I take grapefruit juice while on Siloford 8mg Tablet 10?

No, avoid grapefruit juice while taking Siloford 8mg Tablet 10, as it can increase medicine exposure and potentially lead to an overdose.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

GODOWN NO. B/19 PART-2, GUJRAT ESTATE SARKHEJ SANAND ROAD, SARKHEJ AHMEDABAD Ahmedabad GJ 382210 IN

Country of origin: INDIA

References

Silodosin: MedlinePlus drug information. (n.d.). MedlinePlus Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a609002.html
Villa L, Capogrosso P, Capitanio U, Martini A, Briganti A, Salonia A, Montorsi F. (2022). Silodosin: An Update on Efficacy, Safety and Clinical Indications in Urology. Adv Ther. 2019 Jan;36(1):1-18. https://pubmed.ncbi.nlm.nih.gov/30523608/
Jindan L, Xiao W, Liping X. Evolving Role of Silodosin for the Treatment of Urological Disorders A Narrative Review. Drug Des Devel Ther. 26;16:2861-2884. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9427207/
Silodosin uses, side effects & warnings. (n.d.). Drugs.com https://www.drugs.com/mtm/silodosin.html
Silodosin: Package insert. (n.d.). Drugs.com https://www.drugs.com/pro/silodosin.html

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