Sinate Od Tablet 30

Serum Institute Of India Ltd

Strip of 30 Units

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MRP ~~₹264~~

₹216.48

₹8.80/Units

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Composition

Doxylamine (20 Mg) + Folic Acid (5 Mg) + Vitamin B6 / Pyridoxine (20 Mg)

Sinate-Od Tablet is primarily used to manage nausea and vomiting during pregnancy in women whose symptoms persist even after other management strategies. This medicine is a combination medication, falling under the category of anti-nausea medications.

In addition to managing morning sickness, this medicine has an important role in promoting healthy foetal development. By providing essential nutrients, it helps support the growth and wellness of the developing foetus.

Before starting this medicine, you should consult your doctor for advice on dosage and frequency. It's also important to inform your doctor about any ongoing medicines or pre-existing conditions you might have. If any side effects occur while taking this medicine, make sure to notify your doctor promptly. For best results, take the Sinate-Od Tablet for the duration prescribed by your doctor.

Customers also bought

Managing nausea and vomiting during pregnancy.
Providing folic acid supplementation to pregnant women.
Supporting healthy nerve, skin, and red blood cell function.

Directions for Use of Sinate Od Tablet 30

Here's how to take Sinate-Od Tablet:

Swallow the tablet whole with water.
Do not chew, crush or split the tablet.
It's suggested to take this medication on an empty stomach.
Do not exceed the recommended dosage without consulting your doctor.

Sinate-Od Tablet is taken orally.

The following common side effects may occur when taking Sinate-Od Tablet:

Dizziness
Rash
Disorientation
restlessness
Drowsiness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Sinate-Od Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Drowsiness: Consider taking Sinate-Od Tablet at night if it makes you feel sleepy during the day.
Restlessness: If you feel restless after taking this medicine, try to take it when you have some time to relax afterwards.

Sinate-Od Tablet is composed of three potent ingredients:

Doxylamine Succinate (20 mg): As an antihistamine, doxylamine works by blocking histamine, a substance that can cause allergy symptoms in your body. In doing so, it helps reduce nausea and vomiting associated with pregnancy.
Vitamin B6/Pyridoxine Hydrochloride (20 mg): This B-vitamin contributes to the health of nerves, skin, and red blood cells. Pyridoxine can be used together with doxylamine to effectively manage nausea and vomiting during pregnancy.
Folic Acid (5 mg): This B-vitamin is crucial for creating healthy red blood cells. More importantly for pregnant women, folic acid aids in preventing neural tube defects in the developing foetus during early pregnancy.

Pregnancy

Sinate-Od Tablet is meant for managing nausea and vomiting during pregnancy. However, you should always consult your doctor before taking this medicine.

Breastfeeding

Use of Sinate-Od Tablet during breastfeeding is contraindicated due to the potential for sedation in the infant. Please discuss this with your doctor before starting this medicine.

Alcohol

Concurrent use of alcohol and Sinate-Od Tablet is contraindicated, as it could lead to severe drowsiness which may increase the risk of falls or accidents.

Liver

If you have any liver issues, it's best to consult your doctor before taking Sinate-Od Tablet. Your doctor can decide whether this medicine is suitable for you based on your health status.

Kidney

Caution is advised while taking Sinate-Od Tablet if you have a history of any kidney problems. It's always a good idea to consult your doctor before starting this medicine.

Using Machines & Driving

Sinate-Od Tablet may cause drowsiness or sleepiness due to its anticholinergic properties. Avoid activities requiring complete mental alertness, such as driving or operating heavy machinery, while using this medicine until cleared by your doctor.

Allergy

If you are allergic to doxylamine succinate, other ethanolamine derivative antihistamines, pyridoxine hydrochloride or any inactive ingredients in the formulation, avoid taking Sinate-Od Tablet.

Children

Caution is advised while giving Sinate-Od Tablet to children under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Sinate-Od Tablet under medical supervision as they may be more susceptible to its side effects. If you are above 70 years of age or have liver and kidney issues, it is advised to consult your doctor before using this medicine.

Drug-Drug Interactions

Sinate-Od Tablet interacts with the following medicines:

Monoamine oxidase inhibitors (MAOIs): Medicines like phenelzine and tranylcypromine can interact with Sinate-Od Tablet, potentially increasing and extending the impact of doxylamine on the central nervous system.
Central Nervous System (CNS) depressants: When taken with Sinate-Od Tablet, CNS depressants like benzodiazepines and barbiturates can intensify drowsiness, thereby increasing the risk of accidents or falls.

Drug-Food Interactions

Sinate-Od Tablet is not known to interact with food. Consult your doctor for more information.

Drug-Disease Interactions

Sinate-Od Tablet interacts with the following diseases:

Asthma: The anticholinergic properties of doxylamine in Sinate-Od Tablet may cause breathing difficulties in people with asthma.
Glaucoma: Patients with this eye condition should use Sinate-Od Tablet cautiously as it may increase the pressure within the eye.
Stenosing peptic ulcer: This medicine should be used carefully in individuals suffering from this type of stomach ulcer due to the potential for gastric obstruction.
Urinary bladder-neck obstruction: Doxylamine's anticholinergic effects could aggravate this condition, so caution is advised when using Sinate-Od Tablet.

Daily Dose

Sinate-Od Tablet needs to be taken as directed by your doctor, who will determine your dosage based on factors like your health condition and response to the medicine. Always adhere to the prescribed dosage and never alter it without consulting your doctor.

Over Dose

Taking more Sinate-Od Tablets than prescribed could lead to unpleasant side effects such as drowsiness or upset stomach. If you suspect an overdose, let your doctor know.

Missed Dose

In case you forget to take Sinate-Od Tablet at the usual time, take it as soon as you remember. If it's close to the time for your next dose, skip the missed one and stick to your regular schedule. Do not increase the dose without speaking to your doctor.

Store Sinate-Od Tablet at room temperature, specifically below 30°C.
Keep the medicine away from light and moisture to maintain its effectiveness.
Always keep Sinate-Od Tablet out of reach of children to ensure their safety.
Use the medicine before the expiry date.

Stay hydrated: Drinking plenty of fluids can help manage nausea and vomiting associated with pregnancy.
Eat smaller, more frequent meals: Instead of three large meals, consider having five or six smaller meals throughout the day. This can help prevent an empty stomach, which may trigger nausea in some pregnant women.

Fact Box

Drug Category	Antihistamine, Vitamins
Therapeutic Category	Antiemetic, Nutritional Supplement
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Nausea and Vomiting during Pregnancy, Folate Deficiency

What does Sinate-Od Tablet contain?

Sinate-Od Tablet contains doxylamine succinate (20 mg), vitamin B6 or pyridoxine hydrochloride (20 mg), and folic acid (5 mg).

How does Sinate-Od Tablet work?

The tablet works by combining an antihistamine (doxylamine), which reduces nausea, with folic acid and pyridoxine, both essential for healthy cell formation.

Who should take Sinate-Od Tablet?

This medicine is for women experiencing nausea and vomiting during pregnancy when other management methods haven't worked.

How should Sinate-Od Tablet be taken?

Take Sinate-Od Tablet orally as prescribed by your doctor. If symptoms persist, consult your doctor about adjusting the dose.

Can I take Sinate-Od Tablet if I'm breastfeeding?

Sinate-Od Tablet isn't recommended during breastfeeding as it may cause sedation in the infant.

Are there any side effects of Sinate-Od Tablet?

The most common side effect is somnolence or sleepiness. If you experience this, avoid activities requiring full alertness.

Can I use other medicines while taking Sinate-Od Tablet?

Avoid using monoamine oxidase inhibitors (MAOIs) and CNS depressants while taking Sinate-Od Tablet; consult your doctor for advice.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Snigdha Sharma

Clinical Health & Medical Reviewer | 6 years

MBBS

Check out Editorial Policy

Manufacturer details

212/2, Hadapsar, Off Soli Poonawalla Road, Pune 411028 India

Country of origin: INDIA

References

DICLEGIS (doxylamine succinate and pyridoxine hydrochloride) label. (2016). U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/209661lbl.pdf
New Drug Application (083141). (n.d.). U.S. Food and Drug Administration. https://www.accessdata.fda.gov/drugsatfda_docs/nda/pre96/083141.pdf
Doxylamine: MedlinePlus drug information. (n.d.). MedlinePlus Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682537.html
Pyridoxine: MedlinePlus drug information. (n.d.). MedlinePlus Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a682587.html
How and when to take folic acid. (2022). nhs.uk. https://www.nhs.uk/medicines/folic-acid/how-and-when-to-take-folic-acid/

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