Subitral 50 Mg Capsule 10

Subitral 50 MG Capsule 10

Indoco Remedies Ltd

Strip of 10 Units

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MRP ~~₹90~~

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Prescription required for this medicine

Store Below 30^o C

Composition

Itraconazole (50 Mg)

Strength:

100 MG 50 MG

Subitral 50 MG Capsule 10 is primarily employed to manage various fungal infections caused by Trichophyton species, Microsporum species, and Epidermophyton floccosum. It's part of a group of medicines known as antifungals.

The medicine also helps manage ringworm infections of the skin, hair, and nails. It's suitable for managing oral and esophageal candidiasis caused by Candida species and systemic fungal infections such as aspergillosis, cryptococcosis, histoplasmosis, and blastomycosis.

Remember to take this medicine orally as directed by your doctor. Before starting this medicine, let your doctor know about any pre-existing conditions or ongoing medications. Report any side effects promptly to your doctor. For the best outcome, continue taking the medicine for the duration prescribed by your doctor.

Subitral 50 MG Capsule 10 is used for managing these conditions:

Ringworm infections of the skin, hair, and nails
Oral and oesophageal candidiasis
Systemic fungal infections such as aspergillosis
Cryptococcosis, histoplasmosis, and blastomycosis

Directions for Use of Subitral 50 MG Capsule 10

Follow the precise dosage and timing instructions provided by your doctor.
Do not change or exceed the prescribed dose without consulting your doctor.
Consult your doctor before discontinuing the medication; do not stop taking it without their guidance.
Adhere to the dietary recommendations given by your doctor.

Subitral 50 MG Capsule 10 is taken orally.

Side Effects of Subitral 50 MG Capsule 10

Taking Subitral 50 MG Capsule 10 may result in the following common side effects:

Headache
Nausea and vomiting
Abdominal pain
Diarrhoea
Rash
Dizziness

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve by discontinuing the use of Subitral 50 MG Capsule 10. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Nausea and Vomiting: Follow the dietary recommendations provided by your doctor.
Abdominal Pain: Take Subitral 50 MG Capsule 10 after light meals to lessen this effect.

Subitral 50 MG Capsule 10 contains itraconazole (50 mg) and works on the body in the following ways:

Inhibits fungal enzyme: Itraconazole acts by blocking a fungal enzyme called lanosterol 14α-demethylase. This particular enzyme is critical for the production of ergosterol, a significant component of the fungal cell membrane.
Disrupts cell membrane: By impeding the synthesis of ergosterol, itraconazole increases the permeability of the fungal cell membrane, leading to the release of essential cellular components.
Leads to fungal cell death: The disruption caused to the fungal cell membrane eventually results in the death of the fungal cell.

Through these mechanisms, Subitral 50 MG Capsule 10 effectively manages a variety of fungal infections.

Pregnancy

Caution is advised while taking Subitral 50 MG Capsule 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

Subitral 50 MG Capsule 10 is not recommended for breastfeeding women. Consult your doctor to understand the potential risks and benefits.

Alcohol

There's no known interaction between Subitral 50 MG Capsule 10 and alcohol, but it's always good practice to discuss your alcohol consumption with your doctor.

Liver

Caution is advised while taking Subitral 50 MG Capsule 10 in case of liver issues. If you have liver problems, discuss them with your doctor before starting this medicine. This medicine may affect liver function.

Kidney

Caution is advised before using Subitral 50 MG Capsule 10 if you have a history of kidney problems. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

No particular caution needs to be taken while driving or operating machinery when on Subitral 50 MG Capsule 10, but if you experience side effects such as dizziness, avoid these activities until you feel better.

Allergy

Avoid taking this medicine if you know you're allergic to itraconazole or other ingredients in Subitral 50 MG Capsule 10. Always inform your doctor about any known allergies.

Children

Subitral 50 MG Capsule 10 should be given to children under 18 years of age only under medical supervision. Always consult your doctor before giving this medicine.

Older Patients

Older patients should take Subitral 50 MG Capsule 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Interactions of Subitral 50 MG Capsule 10

Drug-Drug Interactions

Subitral 50 MG Capsule 10 interacts with the following medicines:

Statins: Medicines like simvastatin and lovastatin may interact with Subitral 50 MG Capsule 10, potentially leading to an increased risk of muscle damage.
Benzodiazepines: When taken with Subitral 50 MG Capsule 10, benzodiazepines like midazolam and triazolam may have their effects increased.
Calcium Channel Blockers: Medicines such as felodipine and nisoldipine can interact with Subitral 50 MG Capsule 10, possibly leading to an enhanced blood-pressure-lowering effect.
Immunosuppressants: The effectiveness of immunosuppressants like cyclosporine and tacrolimus may be increased when used with Subitral 50 MG Capsule 10.
Anticoagulants: Co-administration of warfarin with Subitral 50 MG Capsule 10 may increase the risk of bleeding.

Drug-Food Interactions

There are no specific food items that interact with this medicine.

Drug-Disease Interactions

Subitral 50 MG Capsule 10 interacts with the following diseases:

Liver Disease: If you have a history of liver disease, use Subitral 50 MG Capsule 10 cautiously as it can worsen liver function.
Heart Failure: Patients with heart failure need to be careful while taking this medication, as it can exacerbate their condition.

Daily Dose

The daily recommended dose of Subitral 50 MG Capsule 10 should be taken as per your doctor's instructions. Your dosage may vary based on individual factors, such as the severity of your condition and your response to the medicine. It's crucial to follow your doctor's prescribed dosage and not to exceed it without consultation.

Over Dose

Overdosing on Subitral 50 MG Capsule 10 might lead to common side effects like nausea, vomiting, diarrhoea, and stomach pain. If you've accidentally taken more than the prescribed dosage and have these symptoms, it's important to let your doctor know.

Missed Dose

If you've missed a dose of Subitral 50 MG Capsule 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the one you missed and continue with your normal schedule. Always avoid taking extra medicine without speaking to your doctor first.

Store Subitral 50 MG Capsule 10 at a temperature below 30°C.
Keep it in a dry place, shielded from bright light and excessive moisture.
Always ensure it is kept out of the reach and sight of children.
Use it before the expiry date printed on the product packaging.

Fungal infections often thrive in warm, moist environments. Keep your skin clean and dry. This can help manage the conditions for which Subitral 50 MG Capsule 10 is prescribed.
Ensure a balanced diet rich in fruits, vegetables, and whole grains. This can boost your immune system and aid your body in fighting off fungal infections.

Fact Box

Drug Category	Fungal Enzyme Inhibitor
Therapeutic Category	Antifungal
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Ringworm Infections, Candidiasis, Aspergillosis

What is Subitral 50 MG Capsule 10 used for?

It manages various fungal infections such as ringworm, oral and oesophagal candidiasis, and systemic fungal infections like aspergillosis.

How does Subitral 50 MG Capsule 10 work?

It contains an active ingredient called itraconazole, which reduces fungal growth by disrupting a vital process in their cells, resulting in fungal cell death.

How should Subitral 50 MG Capsule 10 be taken?

To improve absorption, the medicine should be swallowed whole with a meal. You should also follow your doctor's instructions regarding the duration and frequency of use.

What are the common side effects of Subitral 50 MG Capsule 10?

Common side effects include headache, nausea, vomiting, abdominal pain, diarrhoea, rash, and dizziness. Consult your doctor if you experience any of these symptoms.

Are there any precautions to take while using Subitral 50 MG Capsule 10?

Yes, individuals with liver disease should use this medication with caution. Also, inform your doctor about any other medications you are currently taking.

Can Subitral 50 MG Capsule 10 be taken during pregnancy or while breastfeeding?

It's classified as pregnancy category C, which means potential risk to the foetus. It is also passed into breast milk, so consult your doctor before using it.

What if I accidentally take more than the prescribed dose of Subitral 50 MG Capsule 10?

Overdosage might cause nausea, vomiting, diarrhoea, and abdominal pain. If this happens, seek medical help immediately.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

Indoco House, 166 CST Road, Kalina, Santacruz (East),

Country of origin: INDIA

References

U.S. National Library of Medicine. (2024). Label: Itraconazole- Itraconazole capsule. DailyMed. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=68165d90-953c-e2f5-e053-2a91aa0ada25
U.S. Food and Drug Administration. (2018). Itraconazole clinical pharmacology review. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2018/208901Orig1s000OtherR.pdf
Itraconazole: MedlinePlus drug information. (2023, April 15). MedlinePlus - Health Information from the National Library of Medicine. https://medlineplus.gov/druginfo/meds/a692049.html
Itraconazole - StatPearls - NCBI bookshelf. (2023, April 17). National Center for Biotechnology Information. https://www.ncbi.nlm.nih.gov/books/NBK557874/

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