Tazomac 45 Gm Injection 1

Tazomac 4.5gm Injection 1

Macleods Pharmaceuticals Pvt.ltd

Vial of 1 UNIT

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MRP ~~₹296.23~~

₹242.91

₹296.23/UNIT

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Composition

Piperacillin (4 Gm) + Tazobactam (0.5 Gm)

Tazomac Injection is primarily used to manage a wide range of bacterial infections. This medicine is a combination, belonging to the penicillin class of antibiotics.

Besides its main use, Tazomac can also be employed for additional purposes. These include combating lower respiratory tract infections like hospital-acquired pneumonia and ventilator-associated pneumonia, intra-abdominal infections, gynecological infections, skin and soft tissue infections, urinary tract infections and kidney infections. It is also effective in managing septicemia (blood infection) and may be used as a preventive measure before certain surgeries.

It is essential to consult your doctor for the correct dosage and frequency. Inform your doctor about any pre-existing diseases or ongoing medication before starting this medicine. Any side effects should be promptly reported to your doctor. Furthermore, it's crucial to continue this medication for the duration prescribed by your doctor for optimal results.

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Tazomac Injection is used for the management of the following conditions:

Lower respiratory tract infections, including hospital-acquired pneumonia and ventilator-associated pneumonia
Intra-abdominal infections such as complicated appendicitis or peritonitis
Gynecological infections like endometritis and pelvic inflammatory disease
Skin and soft tissue infections, particularly diabetic foot infections
Urinary tract infections (UTIs) and kidney infections
Blood infection, and other severe systemic infections
Prophylaxis before certain surgeries to prevent potential infection

Directions for Use of Tazomac 4.5gm Injection 1

Administer Tazomac Injection with these steps in mind:

Tazomac Injection is administered directly into a vein under medical supervision.
Ensure that the injection site is clean before administration.
The injection should be given slowly over a period of 30 minutes.
Never try to administer this medicine at home without professional help.
Always consult your doctor for personalized directions on how to use this medicine.

Tazomac Injection is administered intravenously.

Side Effects of Tazomac 4.5gm Injection 1

Tazomac Injection may have the following common side effects:

Diarrhea
Nausea
Vomiting
Abdominal Pain
Constipation
Altered Taste
Rash
Itching
Inflammation or pain at injection site

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Tazomac Injection. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhea: Ensure you stay hydrated by drinking plenty of fluids.
Nausea: Try having small meals throughout the day rather than three large ones.

Tazomac Injection contains two active ingredients:

Piperacillin (4 GM): This is a broad-spectrum, semisynthetic penicillin derivative. It manages bacterial growth by interfering with the formation of the bacterial cell wall.
Tazobactam (0.5 GM): As a beta-lactamase inhibitor, tazobactam prevents resistant bacteria from inactivating piperacillin, which extends its antibacterial activity.

Together, these two components provide effective coverage against many types of bacteria and help manage numerous bacterial infections successfully.

Pregnancy

Caution is advised while taking Tazomac Injection if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, using Tazomac Injection should be done with caution. Discuss the potential risks and benefits with your doctor.

Alcohol

No specific information is available about the interaction of Tazomac Injection and alcohol. However, it's always wise to avoid or limit alcohol consumption while on medication. Consult your doctor for guidance.

Liver

If you have liver health issues, discuss them with your doctor before starting Tazomac Injection. This medicine may affect liver function, so close monitoring is required.

Kidney

Tazomac Injection should be used with caution if you have kidney problems. Your doctor will guide you based on your health status.

Using Machines & Driving

No specific data suggests that Tazomac Injection affects your ability to drive or operate machinery. But if you experience any side effects like dizziness or fatigue, avoid such activities until you feel better.

Allergy

If you're allergic to penicillins or beta-lactamase inhibitors, do not use Tazomac Injection. Tell your doctor about any history of allergies to ensure this medicine is safe for you.

Children

Tazomac Injection is only recommended for children above 2 months of age under medical supervision. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should use Tazomac Injection under medical supervision as they may be more susceptible to its side effects. If you're above 70 years of age, discuss any liver and kidney issues with your doctor before starting this medicine.

Interactions of Tazomac 4.5gm Injection 1

Drug-Drug Interactions

Tazomac Injection interacts with the following medicines:

Blood Thinners: Tazomac Injection may increase the effects of medicines like warfarin and heparin, potentially leading to an increased risk of bleeding.
Chemotherapy Agents: Certain cancer medications such as methotrexate can interact with Tazomac Injection, potentially increasing their toxicity.
Gout Medicines: Medicines used to manage gout, like probenecid, can interfere with the renal excretion of Tazomac Injection, thereby increasing its blood levels and potential side effects.
Live Vaccines: Tazomac Injection may decrease the effectiveness of live vaccines such as BCG or typhoid vaccine.

Drug-Food Interactions

Tazomac Injection does not have any known significant interactions with food.

Drug-Disease Interactions

Tazomac Injection interacts with the following diseases:

Allergic Reactions: Patients with a history of severe allergic reactions to penicillin antibiotics or beta-lactamase inhibitors should avoid using Tazomac Injection.
Kidney Disease: Tazomac Injection is eliminated through kidneys, and hence patients with kidney disease may require dose adjustment to prevent drug accumulation and toxicity.
Liver Disease: People with liver disease should be cautious while using Tazomac Injection as it could potentially affect liver function.
Seizures: Patients with a history of seizures should use Tazomac Injection cautiously as it could potentially increase seizure frequency.

Daily Dose

The daily dose of Tazomac Injection should be administered as prescribed by your doctor. The dosage may vary depending on factors like how severe your condition is and how you're responding to the medication. It's crucial that you stick to the prescribed dosage and don't exceed it without consulting your doctor.

Over Dose

An overdose of Tazomac Injection could potentially result in side effects such as diarrhoea, nausea, or skin rashes. If you suspect you've been given too much of this medication, inform your doctor promptly.

Missed Dose

If you miss a dose of Tazomac Injection, arrange for it to be administered as soon as you remember. However, if it's almost time for your next scheduled dose, skip the missed one and continue with your regular schedule. Never alter your dosage without consulting your doctor.

Keep Tazomac Injection in a cool, dry place, ideally below 25°C.
Protect the product from light.
Safeguard the injection from children's reach.
Make sure to use the injection before its expiry date.

If you have urinary tract infections (UTIs) or kidney infections for which Tazomac Injection is administered, remember to drink plenty of fluids. This helps flush bacteria out of your urinary system.
For skin and soft tissue infections like diabetic foot infections, maintaining good blood sugar control through diet and exercise can help manage the infection. Avoid foods high in simple sugars and engage in regular physical activity.

Fact Box

Drug Category	Cell Wall Synthesis Inhibitor
Therapeutic Category	Antibiotic
Available Dosage Types	Injection
Habit Forming	No
Ailment	Pneumonia, Appendicitis, Urinary Tract Infections

1) What is Tazomac Injection used for?

Tazomac Injection is administered to manage serious bacterial infections like pneumonia, intra-abdominal infections, gynaecological infections, UTIs, and septicemia.

2) How does Tazomac Injection work?

Tazomac Injection contains two medicines - piperacillin and tazobactam. Piperacillin stops bacteria from growing by interfering with their cell walls, and tazobactam extends its effectiveness.

3) Who should not use Tazomac Injection?

Those with severe allergies to penicillin antibiotics, cephalosporins or beta-lactamase inhibitors should avoid Tazomac Injection. Consult your doctor if you have kidney disease or a history of seizures.

4) Can I use Tazomac Injection during pregnancy?

The safety of Tazomac Injection during pregnancy is not well established. Always consult your doctor before using any medication if you're pregnant.

5) How is Tazomac Injection administered?

Tazomac Injection is administered directly into a vein by a healthcare professional, typically in a hospital or clinical setting. It should never be self-administered.

6) What are the common side effects of Tazomac Injection?

Common side effects include nausea, diarrhoea, vomiting, rash, headache and changes in taste. If you experience persistent or severe side effects, contact your doctor immediately.

7) How should I store Tazomac Injection?

Store the dry powder below 25°C, away from light. Once mixed into a solution, it's stable for 24 hours at room temperature or 48 hours refrigerated.

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 5 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 10 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Atlanta Arcade, Marol Church Rd, Bori Colony, Vijay Nagar Colony West, Marol, Andheri East, Mumbai, Maharashtra 400059

Country of origin: INDIA

References

U.S. National Library of Medicine. (2022). Piperacillin and Tazobactam Injection. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a694003.html
U.S. Food and Drug Administration. (2009). Zosyn (Piperacillin and Tazobactam) Injection. FDA. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/065386lbl.pdf

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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