Tenvir L 300/300 MG Tablet 10

Cipla Ltd.

Pack of 10 Units
BOTTLE of 30 Units

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MRP ~~₹1415.5~~

₹1132.4

₹141.55/Units

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Composition

Lamivudine (300 Mg) + Tenofovir Disoproxil Fumarate (300 Mg)

Tenvir L 300/300 MG Tablet is primarily used to treat HIV (human immunodeficiency virus) infection in adults, adolescents and children weighing at least 30 kg. This medication belongs to the class of nucleotide reverse transcriptase inhibitors (NRTIs).

This tablet is also used to reduce the risk of getting HIV‐1 infection in adults and adolescents (weighing at least 35 kg) who are not HIV-infected (i.e. HIV‐negative) but are at high risk of getting infected with HIV.

It is essential to take this medicine orally as directed by your doctor. You should inform your doctor about any preexisting conditions or ongoing medications before starting the medicine. If you notice any side effects while on this medicine, it is crucial to notify your doctor immediately. Make sure you continue taking this tablet for the duration prescribed by your doctor for optimal results.

Tenvir L 300/300 MG Tablet is used in the following conditions:

To treat HIV (human immunodeficiency virus) infection in adults, adolescents and children.
To reduce the risk of getting HIV‐1 infection in adults and adolescents (weighing at least 35 kg) who are not HIV infected.

Directions for Use of Tenvir L 300/300 MG Tablet 10

Swallow the tablet whole with a glass of water.
It can be taken with or without food.
Take it at the same time every day for best results.
Do not alter the dosage without consulting your doctor.

Tenvir L 300/300 MG Tablet is taken orally.

Side Effects of Tenvir L 300/300 MG Tablet 10

Common side effects of Tenvir L 300/300 MG Tablet include:

Nausea
Fatigue
Diarrhoea
Dizziness
Headache

If any side effects persist or worsen, consult your doctor immediately.

Managing the Side Effects:

Most side effects are temporary, generally harmless, and resolve upon stopping the use of Tenvir L 300/300 MG Tablet. However, if you experience serious side effects or worsening of any symptoms, notify your doctor.

Here are a few guidelines for managing common side effects:

Nausea: Take the tablet with food to minimise discomfort.
Dizziness: Avoid activities requiring alertness, such as driving.
Fatigue: Rest and stay hydrated.

How Tenvir L 300/300 MG Tablet 10 Works?

Tenvir L 300/300 MG Tablet contains two active components:

Lamivudine (300 mg): It works by blocking the reverse transcriptase enzyme, which prevents the virus from replicating in human cells.
Tenofovir Disoproxil Fumarate (TDF) (300 mg): It inhibits viral replication by interfering with the DNA chain elongation of the virus.

Together, these ingredients help suppress the growth of the HIV virus, thus reducing the risk of complications and improving the patient’s quality of life.

Pregnancy

Avoid using Tenvir L 300/300 MG Tablet unless prescribed by your doctor. Discuss the potential risks and benefits if you are pregnant.

Breastfeeding

Tenvir L 300/300 MG Tablet may pass into breast milk. Breastfeeding is not recommended for mothers with HIV to prevent transmission of the virus to the baby.

Alcohol

Avoid alcohol consumption while taking this medicine, as it may increase the risk of liver damage or worsen side effects.

Liver

Patients with liver impairment or Hepatitis B infection should use Tenvir L 300/300 MG Tablet cautiously. Regular monitoring of liver function is required.

Kidney

Tenvir L 300/300 MG Tablet is not recommended for patients with severe kidney impairment or those undergoing dialysis, as it may worsen renal function.

Using Machines & Driving

Tenvir L 300/300 MG Tablet may affect your ability to drive or operate machinery. If you experience dizziness or any other side effects that may impair your concentration, it is recommended to avoid such activities.

Allergy

Avoid Tenvir L 300/300 MG Tablet if you are allergic to Lamivudine, Tenofovir, or any inactive ingredient in the tablet. Inform your doctor of any known allergies.

Children

Tenvir L 300/300 MG Tablet is approved for use in children weighing at least 35 kg. The dosage should be adjusted by a paediatric specialist.

Older Patients

Elderly patients may have an increased risk of renal and hepatic side effects. Close monitoring is recommended for this age group.

Interactions of Tenvir L 300/300 MG Tablet 10

Drug-Drug Interactions

Tenvir L 300/300 MG Tablet may interacts with:

NSAIDs such as ibuprofen: Using NSAIDs with Tenvir L 300/300 MG Tablet may increase the risk of kidney damage, especially with prolonged use or pre-existing kidney issues.
Antiviral medication such as Ribavirin: Combining Ribavirin with this medication can cause severe liver complications, particularly in patients with advanced liver disease.
Other HIV medications such as Adefovir: Co-administration with Adefovir may result in additive toxicity, heightening the risk of kidney and liver damage.

Drug-Food Interactions

There are no specific food restrictions with this medication.

Drug-Disease Interactions

Patients with the following conditions should use Tenvir L 300/300 MG Tablet cautiously:

Pancreatitis: Patients with a history of pancreatitis should use this medication cautiously, as it may exacerbate the condition.
Liver Dysfunction: This medication should be used with caution in patients with impaired liver function to avoid further complications.
Renal Impairment: Patients with kidney problems must use this medication under strict medical supervision due to the increased risk of toxicity.

Daily Dose

The daily dose of Tenvir L 300/300 MG Tablet should be taken as your doctor prescribes. The dosage may change based on individual factors such as age, the condition's severity, and treatment response.

Over Dose

Overdosing may result in severe side effects, including lactic acidosis, renal dysfunction, or pancreatitis. Seek immediate medical attention in such cases.

Missed Dose

If you miss a dose, take it as soon as you remember. If it is close to the next scheduled dose, skip the missed dose. Never double the dose to make up for a missed one.

Store Tenvir L 300/300 MG Tablet at room temperature (15-25°C), away from direct sunlight and moisture.
Keep the medicine out of reach of children.
Do not use this medicine after the expiry date has passed.

Monitor your bone health as this tablet may affect bone density; include calcium and vitamin D-rich foods in your diet and consult your doctor for supplements if needed.
Avoid smoking and practise safe habits to minimise any further strain on your immune system.

Fact Box

Drug Category	Nucleotide Reverse Transcriptase Inhibitors (NRTIs)
Therapeutic Category	Antiretroviral Therapy (ART)
Available Dosage Types	Tablet
Habit Forming	No
Ailment	HIV-1 Infection

What is Tenvir L 300/300 MG Tablet used for?

This tablet is primarily used for treating HIV-1 infection as part of combination therapy and may also be prescribed for chronic Hepatitis B in certain cases.

How does Tenvir L 300/300 MG Tablet work?

This medication works by inhibiting enzymes essential for the replication of HIV and Hepatitis B viruses, thereby reducing viral load and slowing disease progression.

Can I take Tenvir L 300/300 MG Tablet during pregnancy?

This medication should only be taken during pregnancy if prescribed by a doctor, as they will evaluate the potential benefits and risks to both the mother and baby.

What are the side effects of Tenvir L 300/300 MG Tablet?

Common side effects of this tablet include nausea, diarrhoea, fatigue, and dizziness. These side effects are generally mild but should be reported if persistent or severe.

Can I stop taking Tenvir L 300/300 MG Tablet if I feel better?

No, do not stop taking this medication without consulting your doctor, as discontinuation can lead to worsening of the condition or medication resistance.

Is it safe to take alcohol while on Tenvir L 300/300 MG Tablet?

Alcohol should be avoided while taking this tablet, as it may cause liver damage and increase the likelihood of side effects such as nausea and fatigue.

Last Updated On 27 Jan. 2025 | 5:32AM (IST)

Certified Content

Written by

Dr. Sachin Singh

Medical Team Lead | 6 years

MBBS

Reviewed by

Dr. Mandeep Chadha

Lead Medical Content Reviewer | 11 years

MBBS, DNB (OBGY)

Check out Editorial Policy

Manufacturer details

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Country of origin: INDIA

References

VUDINE AND TENOFOVIR DISOPROXIL FUMARATE(N.d.). Fda.Gov. Retrieved January 12, 2025, from https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/022344PI.pdf
Lamivudine/tenofovir disoproxil fumarate 300mg/300mg tablets. (N.d.). Gov.Rw. Retrieved January 12, 2025, from https://rwandafda.gov.rw/wp-content/uploads/2023/09/Lamivudine
Lamivudine 300 mg and tenofovir disoproxil fumarate 300 mg . (N.d.). Gov.Ng. Retrieved January 12, 2025, from https://www.nafdac.gov.ng/wp-content/uploads/Files/SMPC/Feb2_2022/TamivudineTenofovir-disoproxil-fumarate-Tablets-300300-mg.pdf

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