Tgr 160 Mg Tablet 10

Tgr Tablet 10

Intas Pharmaceuticals Ltd

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Composition

Fenofibrate (160 Mg)

TGR Tablet is primarily used to manage high levels of cholesterol and triglycerides in your blood. This medicine is part of a group of medications known as fibrates, which are used to regulate lipid levels in the body.

Besides managing cholesterol and triglyceride levels, this tablet also helps to increase the level of good cholesterol (HDL) in your blood. It is used for managing conditions such as hyperlipidemia and mixed dyslipidemia (Fredrickson Types IIa and IIb), and reducing the risk of pancreatitis in patients who have extremely high levels of triglycerides.

Before starting this medication, it's important to consult your doctor regarding the appropriate dosage and frequency. Discuss any pre-existing health conditions or ongoing medications with your doctor. While on this medication, if you notice any side effects, promptly inform your doctor. For the best results, continue taking TGR Tablet for the entire duration prescribed by your doctor.

TGR Tablet is utilised for the following:

Decreasing high levels of LDL cholesterol, also known as 'bad' cholesterol
Lowering overall cholesterol levels in the blood
Reducing excessive triglycerides
Boosting HDL cholesterol, often referred to as 'good' cholesterol
Managing medical conditions characterised by abnormally high lipid levels, specifically hyperlipidemia and mixed dyslipidemia (Fredrickson Types IIa and IIb)
Preventing pancreatitis in individuals with very high triglyceride levels

Swallow the tablet whole with a drink of water.
Do not crush or chew the tablet.
Make sure you take this medicine at the same time each day for optimal results.
Always remember to take your medicine during a meal.

TGR Tablet is taken orally.

Taking TGR Tablet could result in the following side effects:

Stomach pain
Nausea and vomiting
Diarrhoea or constipation
Headache and dizziness
Joint pain and back pain
Fatigue
Sleep disturbances: You may experience trouble falling asleep or staying asleep.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of TGR Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are a couple of tips to manage common side effects:

Stomach pain: Try taking TGR Tablet with your meals.
Diarrhoea or constipation: Ensure you drink plenty of fluids while taking this medicine.

TGR Tablet contains fenofibrate (160 mg) which works on your body through several mechanisms:

Activation of PPARα: Fenofibrate activates a receptor in your body called peroxisome proliferator-activated receptor α (PPARα). By doing so, it increases the breakdown of fatty substances in your blood.
Enhanced Lipolysis: The activation of PPARα leads to enhanced lipolysis and removal of particles rich in triglycerides from the blood.
Reduction in Apoprotein C-III Production: Fenofibrate also reduces the production of apoprotein C-III which is involved in fat metabolism.
Alteration of LDL Particles: This medicine alters the size and composition of LDL particles, making them less likely to cause hardening of arteries (atherogenesis).
Increased Affinity for Cholesterol Receptors: Larger LDL particles have a higher affinity for cholesterol receptors due to fenofibrate, leading to rapid catabolism.

Pregnancy

Caution is advised while taking TGR Tablet if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's crucial to discuss with your doctor prior to starting TGR Tablet.

Alcohol

It's recommended to limit alcohol consumption while on TGR Tablet as it may exacerbate certain side effects.

Liver

If you have a history of liver problems, careful consideration is needed before using TGR Tablet. This medicine may affect liver function and should be used with caution in mild to moderate liver impairment.

Kidney

Patients with kidney problems should exercise caution before using TGR Tablet, especially those with severe renal impairment. Always consult your doctor if you have any kidney health concerns.

Using Machines & Driving

TGR Tablet may cause dizziness or fatigue. If these symptoms occur, avoid driving or operating machinery until they subside.

Allergy

If you're allergic to fenofibrate or any other ingredients in TGR Tablet, do not take this medicine. Seek immediate medical attention if an allergic reaction occurs.

Children

TGR Tablet is not recommended for use in children under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take TGR Tablet under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

TGR Tablet interacts with the following medicines:

Anticoagulants: Medicines such as warfarin may have their effects heightened, leading to prolonged prothrombin time/INR when taken with TGR Tablet.
Bile Acid Sequestrants: Medicines like cholestyramine and colestipol can decrease the absorption of fenofibrate, so it's important to take TGR Tablet at least 1 hour before or 4-6 hours after these agents.
Immunosuppressants: Taking cyclosporine with TGR Tablet might increase the risk of renal function impairment.

Drug-Food Interactions

There are no known specific food interactions with TGR Tablet. However, it is generally recommended to maintain a balanced diet for optimal health.

Drug-Disease Interactions

TGR Tablet interacts with the following diseases:

Kidney Disease: Patients with kidney disease or impaired renal function should use TGR Tablet cautiously as it could potentially worsen their condition.
Liver Disease: Individuals with liver diseases or abnormal liver function tests should be careful when taking this medicine as it could exacerbate their condition.
Gallbladder Disease: Those suffering from gallbladder disease or gallstones need to be cautious when using TGR Tablet as it might aggravate their condition.
Hypothyroidism and Diabetes Mellitus: Patients diagnosed with hypothyroidism or diabetes mellitus need to be cautious while using this medicine as it could potentially affect their disease management.

Daily Dose

The dosage of TGR Tablet should be as recommended by your doctor. This dose may vary depending on factors such as the severity of your condition and how you respond to the medication. It's crucial to stick to the prescribed dosage and not to exceed it without consulting your doctor.

Over Dose

In case of an accidental overdose of TGR Tablet, you may experience symptoms like stomach pain, diarrhoea, headache, and fatigue. If you notice these or any other unusual symptoms, inform your doctor.

Missed Dose

If you miss a dose of TGR Tablet, take it as soon as you recall. However, if it's nearly time for your next dose, skip the missed one and continue with your usual schedule. Remember to never increase your dosage without consulting your doctor.

Store TGR Tablet at room temperature below 30°C.
Keep the medicine away from direct light and moisture.
Always keep TGR Tablet out of reach of children.
Make sure to use this medicine before its expiry date.

Since TGR Tablet manages high cholesterol, incorporate a low-fat, high-fibre diet into your meal plan. This includes fruits, vegetables, and whole grains.
Regular physical activity can help control your cholesterol levels. Aim for at least 30 minutes of exercise most days of the week.

Fact Box

Drug Category	PPARα Activator
Therapeutic Category	Lipid-Regulating Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	High Cholesterol, Hyperlipidemia, Mixed Dyslipidemia

What is TGR Tablet used for?

TGR Tablet is used to manage high levels of bad cholesterol, total cholesterol, and triglycerides in the blood.

How does TGR Tablet work?

TGR Tablet works by enhancing the breakdown of fatty substances in your blood, thus improving your lipid profiles.

Can I take TGR Tablet with food?

Yes, it's advisable to take TGR Tablet with meals as this optimises the absorption of fenofibrate into your body.

Are there any side effects to TGR Tablet?

Common side effects include stomach pain, nausea, diarrhoea, headache and joint pain. Serious side effects should be reported to your doctor immediately.

Are there any precautions I need to take when using TGR Tablet?

Caution is needed if you have kidney or liver disease, gallbladder disease, thyroid problems or diabetes. Always inform your doctor about these conditions.

Can TGR Tablet interact with other medicines?

Yes, TGR Tablet can interact with certain medicines like anticoagulants and immunosuppressants. Always consult your doctor about other medicines you are taking.

How should I store TGR Tablet?

Store your TGR Tablet at room temperature, away from light and moisture. Keep it out of reach from children and pets.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

HIGHLIGHTS OF PRESCRIBING INFORMATION. (2018). [Prescribing information]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021656s029lbl.pdf
Fenofibrate: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB01039
Sidhu, G., & Tripp, J. (2023, March 13). Fenofibrate. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK559219/
Ezhov, M. V., & Arutyunov, G. P. (2023). Effectiveness and Safety of Fenofibrate in Routine Treatment of Patients with Hypertriglyceridemia and Metabolic Syndrome. Diseases, 11(4), 140. https://doi.org/10.3390/diseases11040140
Gunwal, D., Dutt, B., Choudhary, M., & Budhwar, V. (2021, August 5). A comprehensive review on the drug: fenofibrate. International Journal of Research in Pharmaceutical Sciences -. https://ijrps.com/index.php/home/article/view/238

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