Topiranol 50 Mg Tablet 10

Topiranol 50 Tablet 10

Knoll Healthcare Pvt. Ltd.

Strip of 10 Units

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MRP ~~₹181.3~~

₹90.47

₹18.13/Units

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Composition

Topiramate (50 Mg)

Strength:

50 MG 25 MG

Topiranol 50 Tablet 10 is primarily used to manage certain types of seizure disorders. It falls under the category of anticonvulsants.

It is also effective in preventing migraines in adults and adolescents aged 12 years and above. However, it is not designed to stop an ongoing acute migraine attack.

Take this medicine as advised by your doctor. Before starting the medication, inform them about any pre-existing health conditions or medicines you are on. If you experience any side effects while on this medication, notify your doctor. Continue taking this tablet for the entire duration prescribed by your doctor for maximum benefit.

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Topiranol 50 Tablet 10 is used for managing the following conditions:

Controlling partial onset or primary generalised tonic-clonic seizures in patients of age 2 years and older
Assisting with the management of seizures associated with Lennox-Gastaut syndrome when used with other antiepileptic medications
Helping prevent migraine attacks in adults and adolescents aged 12 years and older, however, it doesn't stop acute migraine attacks

Directions for Use of Topiranol 50 Tablet 10

Here's how to take Topiranol 50 Tablet 10:

Swallow the tablet whole without breaking or chewing.
Take it with or without food, as you prefer.
Stay well-hydrated during the course of the medicine to reduce the risk of kidney stones.
If unsure about any aspect of using this medicine, consult your doctor for proper dosage guidance.

Topiranol 50 Tablet 10 is taken orally.

You might experience the following common side effects upon taking Topiranol 50 Tablet 10:

Fatigue
Drowsiness
Cognitive slowing
Abdominal pain
Nausea
Paraesthesia: Tingling or pricking sensation, often described as 'pins and needles.'
Anorexia: Less appetite than usual

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Topiranol 50 Tablet 10. However, if you experience serious side effects or worsening of symptoms, consult your doctor.

Here are some tips for managing common side effects:

Anorexia: Try taking this tablet with food to lessen this effect.
Abdominal pain: If you have abdominal pain, take this medicine after meals to reduce discomfort.

Topiranol 50 Tablet 10 contains topiramate (50 mg), and its therapeutic functions are as follows:

Reduction in neuronal firing: Topiramate helps block certain channels in your body that allow sodium ions to pass through, reducing sustained repetitive neuronal firing.
Enhancement of neurotransmission: It enhances the activity of GABA-mediated chloride channels, leading to an increase in inhibitory neurotransmission.
Decreases excitatory neurotransmission: Topiramate acts against AMPA/kainate glutamate receptors, which helps reduce excitatory neurotransmission.
Inhibits carbonic anhydrase: It also inhibits carbonic anhydrase isoenzymes II and IV.

These actions together help in suppressing seizure activity, preventing the spread to neighbouring neurons, and stabilising hyperexcitable neurons.

Pregnancy

If you are pregnant, Topiranol 50 Tablet 10 is not recommended. Consult your doctor before using this medicine.

Breastfeeding

It's advised that mothers who are breastfeeding proceed with caution when taking Topiranol 50 Tablet 10. Discuss potential risks and benefits with your doctor.

Alcohol

While taking Topiranol 50 Tablet 10, avoid alcohol as it may increase drowsiness and sedation. Discuss with your doctor if you have any concerns.

Liver

For those with mild to moderate liver impairment, use Topiranol 50 Tablet 10 with caution. It is not recommended for people with severe liver diseases. Discuss your liver health with your doctor before starting this medicine, as it may affect liver function.

Kidney

If you have any kidney problems, be cautious before taking Topiranol 50 Tablet 10. Consult your doctor before starting this medicine.

Using Machines & Driving

Topiranol 50 Tablet 10 may cause fatigue and dizziness which could impact your ability to drive or operate machinery. Ensure you understand how the medicine affects you before engaging in such activities.

Allergy

If you're allergic to topiramate or any other inactive ingredient in the formulation, Topiranol 50 Tablet 10 is contraindicated. Discuss any allergies with your doctor before starting this medication.

Children

Topiranol 50 Tablet 10 can be used in children for managing seizures in children aged 2 years and older and for migraine prevention in children aged 12 years and above. Always consult a paediatrician before giving this medication to your child.

Older Patients

Older patients may be more susceptible to side effects of Topiranol 50 Tablet 10 and should take it under medical supervision. If patients are above 70 years of age or have liver or kidney issues, they should consult their doctor before starting this medication.

Drug-Drug Interactions

Topiranol 50 Tablet 10 interacts with the following medicines:

CNS depressants: Medicines like diazepam and alprazolam may enhance the drowsiness and sedation effect when taken with this tablet.
Oral contraceptives: The efficacy of contraceptive pills like ethinylestradiol and levonorgestrel may be reduced when used with this tablet.
Carbonic anhydrase inhibitors: Medicines like acetazolamide and zonisamide may increase the risk of kidney stones and metabolic acidosis when used with this tablet.
Diuretics: This may interact with this tablet, increasing the risk of low potassium levels in your blood (hypokalaemia).
Antiepileptic medications: Like phenytoin, valproic acid can interact with this tablet, causing high ammonia levels in your blood (hyperammonaemia) and low body temperature (hypothermia).
Antidepressants: Like with fluoxetine, amitriptyline plasma levels can increase when used with this tablet, which could potentially lead to more side effects.

Drug-Food Interactions

Topiranol 50 Tablet 10 has no known interactions with any specific foods.

Drug-Disease Interactions

Topiranol 50 Tablet 10 interacts with the following diseases:

Liver dysfunction: Use this medicine carefully if you have liver issues, as it could potentially worsen your condition.
Renal impairment: If you have impaired kidney function, take this medicine cautiously, as it might worsen your condition.
Respiratory depression: People suffering from respiratory depression should be careful as this medicine could potentially worsen their condition.
Angle-closure glaucoma: Patients with this condition should be cautious as this tablet could increase eye pressure, worsening their condition.
Metabolic acidosis: If you're on metformin to manage diabetes and suffering from metabolic acidosis, avoid using this tablet.

Daily Dose

Take Topiranol 50 Tablet 10 as directed by your doctor. Your dosage may vary based on your health condition and your response to the treatment. Adhere to your doctor's prescribed dosage, and don't exceed it without consultation.

Over Dose

If you accidentally take more than your prescribed dose of Topiranol 50 Tablet 10, you may experience dizziness or confusion in a more severe form. In this situation, consult your doctor immediately for guidance.

Missed Dose

If you miss a dose of Topiranol 50 Tablet 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular dosing schedule. Don't increase your dosage without consulting your doctor.

Store Topiranol 50 Tablet 10 in a cool, dry place at room temperature.
Keep the medicine container closed tightly to protect it from moisture.
Do not store in the bathroom as it might increase exposure to moisture.
Always keep this medicine out of reach of children.
Use before the expiry date.

For those managing seizure disorders with Topiranol 50 Tablet 10, try to maintain a regular sleep pattern. Disrupted sleep can sometimes trigger seizures.
If you're using this tablet for migraine prophylaxis, consider reducing your intake of caffeine and chocolate. These can sometimes provoke migraines.

Fact Box

Drug Category	Anticonvulsant
Therapeutic Category	Antiepileptic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Seizure disorders, migraine prophylaxis

What is the function of Topiranol 50 Tablet 10?

Topiranol 50 Tablet 10 manages certain seizure disorders and prevents migraines, but it does not stop an active migraine attack.

Can Topiranol 50 Tablet 10 be used for children?

Yes, for managing seizures, only after medical consultation, it can be used in children aged 2 years and older, and for migraine prevention, in children aged 12 years and above.

What should I do if I miss a dose of Topiranol 50 Tablet 10?

Take the missed dose as soon as you remember unless it's nearly time for your next one. If so, skip the missed dose completely. Do not alter dosage without consulting your doctor.

Can I crush or chew Tormax tablet?

No, swallow Topiranol 50 Tablet 10 whole. Crushing or chewing is not recommended.

How long do I need to take Topiranol 50 Tablet 10 for seizure management?

The optimal duration varies for different individuals. Most patients need long-term use. Always consult your doctor before stopping this medicine.

Are there any side effects of taking Topiranol 50 Tablet 10?

Yes, common side effects include fatigue, dizziness, difficulty concentrating, and stomach upset with diarrhoea and abdominal pain. Consult your doctor if these persist or worsen.

Are there any precautions needed while taking Topiranol 50 Tablet 10?

Yes, it's crucial to maintain adequate hydration while on this medication to reduce the risk of kidney stones.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Divya Chauhan

Medical Writer & Reviewer | 6 years

BAMS, APG, PG

Check out Editorial Policy

Manufacturer details

M17, Pharma Tower,, Phase-1, Badli Industrial Area,, Badli, Delhi, 110042

Country of origin: INDIA

References

U.S. National Library of Medicine. (2022). Topiramate: MedlinePlus Drug Information. MedlinePlus. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a697012.html
U.S. Food and Drug Administration. (2022). TOPIRAMATE- topiramate tablet, film coated [Label]. Accessdata.fda.gov. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/020505s064,020844s054lbl.pdf
National Center for Biotechnology Information (2024). PubChem Compound Summary for CID 5284627, Topiramate. Retrieved June 18, 2024 from https://pubchem.ncbi.nlm.nih.gov/compound/Topiramate.
Topiramate: Uses, Interactions, Mechanism of Action | DrugBank Online https://go.drugbank.com/drugs/DB00273
Arnone D. (2005). Review of the use of Topiramate for treatment of psychiatric disorders. Annals of general psychiatry, 4(1), 5. https://doi.org/10.1186/1744-859X-4-5

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