Tremnil 2 Mg Tablet 10

Tremnil 2 Tablet 10

Shine Pharmaceuticals Ltd

Strip of 10 Units

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MRP ~~₹15.20~~

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Composition

Trihexyphenidyl (2 Mg)

Tremnil-2 Tablet is primarily used to manage symptoms associated with Parkinson's disease. It's part of a group of medicines known as anticholinergic agents, which work by blocking certain chemical messengers in the body.

In addition to managing Parkinson's disease, this medicine can also be used to manage involuntary movements or dyskinesia induced by certain antipsychotic medications. These conditions can lead to uncontrolled movements, stiffness, and restlessness, which this medicine can help manage effectively.

Before you start taking this medicine, it's important to consult your doctor who will decide the appropriate dosage for you. Let your doctor know about any pre-existing conditions or ongoing medications. If you experience any side effects while on this medication, inform your doctor immediately. Continue taking this medicine for the duration prescribed by your doctor for optimal results.

Tremnil-2 Tablet is used for the following:

Managing symptoms of Parkinson's disease: The medicine helps reduce muscle stiffness, tremors, and other movement problems associated with this condition.
Controlling medicine-induced involuntary movements: These are unwanted movements (dyskinesia) caused by certain psychiatric medicines.

Directions for Use of Tremnil 2 Tablet 10

Here are some general instructions to follow while taking Tremnil-2 Tablet:

Swallow the entire tablet with a glass of water. Do not crush or chew it.
Take the medicine at the same time each day to ensure optimal benefits.
Don't take more than your doctor's recommended dose.
If you need any clarification regarding your medication, consult your doctor.

Tremnil-2 Tablet is taken orally.

Taking Tremnil-2 Tablet may lead to the following side effects:

Dry mouth
Constipation
Blurred vision
Dizziness
Nausea
Confusion
Hallucinations: This side effect means that you might see, hear, feel, or smell something that isn't there.
Irregular heartbeat
Difficulty urinating: This could mean you find it hard to start urinating, or you're not able to fully empty your bladder.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Tremnil-2 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some tips on managing a couple of these common side effects:

Dry mouth: Try taking Tremnil-2 Tablet with a glass of water or sucking on ice cubes to alleviate the dryness.
Constipation: Increase your fibre intake and consume plenty of water.

Tremnil-2 Tablet contains one active ingredient, Trihexyphenidyl (2 mg), which works on the body as follows:

Reduction of Acetylcholine Activity: Trihexyphenidyl acts by reducing the activity of acetylcholine, a neurotransmitter that regulates muscle contractions. With less acetylcholine activity, your muscles can relax more easily.
Improved Motor Control: By blocking the effects of acetylcholine, trihexyphenidyl improves the control you have over your body movements. This results in reduced muscle rigidity and tremors, which are common symptoms in conditions like Parkinson's disease and medicine-induced dyskinesia.

Pregnancy

Caution is advised while taking Tremnil-2 Tablet if you are pregnant. It's best to consult your doctor before taking this medicine.

Breastfeeding

Tremnil-2 Tablet is not recommended for breastfeeding women. Discuss with your doctor to understand the potential risks and benefits.

Alcohol

It's advised to discuss with your doctor about the effects of alcohol consumption while on this medication.

Liver

Caution is advised while taking Tremnil-2 Tablet if you have any liver issues. This medicine may affect liver function, so it's important to consult your doctor before starting it.

Kidney

If you have a history of kidney problems, it's a good idea to consult your doctor before taking Tremnil-2 Tablet.

Using Machines & Driving

Tremnil-2 Tablet might cause dizziness or blurred vision. Therefore, caution is advised while driving or operating heavy machinery.

Allergy

Tremnil-2 Tablet is contraindicated for people allergic to trihexyphenidyl or any other components in the tablet. Always inform your doctor about any known allergies.

Children

Take caution while giving Tremnil-2 Tablet to children under 18 years of age. Always consult your doctor before giving this medicine to a child.

Older Patients

Older patients should take Tremnil-2 Tablet under medical supervision as they may be more susceptible to its side effects. If you are above 70, it's important to discuss this with your doctor who can guide you based on your health status.

Drug-Drug Interactions

Tremnil-2 Tablet interacts with the following medicines:

Anticholinergics: Tremnil-2 Tablet, which also contains an anticholinergic (trihexyphenidyl), may interact with other anticholinergic medicines such as atropine and scopolamine, potentially leading to increased side effects like dry mouth and blurred vision.
Antipsychotics: Taking this medication with antipsychotics like chlorpromazine or haloperidol might increase the risk of involuntary movements or other motor effects.
Tricyclic Antidepressants: Medicines like amitriptyline and imipramine might interact with Tremnil-2 Tablet, potentially influencing their intended effects or causing unwanted side effects.
Antihistamines: Concomitant use of antihistamines such as diphenhydramine or promethazine with Tremnil-2 Tablet may enhance the anticholinergic effect.

Drug-Food Interactions

There are no specific known interactions between Tremnil-2 Tablet and any food items.

Drug-Disease Interactions

Tremnil-2 Tablet interacts with the following diseases:

Narrow-angle Glaucoma: This medicine may exacerbate symptoms in people who have narrow-angle glaucoma.
Prostatic Hypertrophy: The condition can be worsened by the use of this medicine as it may lead to urinary retention.
Cardiovascular Disease: Patients suffering from cardiovascular disease should exercise caution while taking this medicine due to potential cardiac side effects.
Renal or Hepatic Impairment: Use of Tremnil-2 Tablet in individuals with renal or hepatic impairment should be under strict medical supervision since its metabolites are excreted through these systems.

Daily Dose

As a patient, you should take the Tremnil-2 Tablet as per your doctor's instructions. The dosage may vary depending on individual factors like how severe your condition is and how you respond to the medication. Always adhere to your prescribed dosage and consult your doctor before changing.

Over Dose

If you accidentally take more Tremnil-2 Tablets than prescribed, you may feel very drowsy or confused. You could also experience hallucinations or a rapid heartbeat. If these symptoms occur, inform your doctor.

Missed Dose

If you forget to take your regular dose of Tremnil-2 Tablet, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one and carry on with your usual schedule. Don't increase your dosage without consulting your doctor.

Store your Tremnil-2 Tablet in a dry place, protected from light and moisture.
Keep the medicine at room temperature, ideally between 15 to 30°C.
Ensure the storage area is out of reach for children.
Use the tablet before the expiry date printed on the pack.

Regular physical activity can help manage Parkinson's symptoms. Try simple exercises like walking or stretching, but remember to consult your doctor before starting any exercise routine.
Maintain a balanced diet rich in fibres. This can help manage constipation, a common side effect of using Tremnil-2 Tablet. Include fruits, vegetables, and whole grains in your meals.

Fact Box

Drug Category	Anticholinergic Agent
Therapeutic Category	Antiparkinsonian
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Parkinson's Disease, Medicine-Induced Extrapyramidal Symptoms

What is Tremnil-2 Tablet used for?

Tremnil-2 Tablet is used to manage muscle rigidity and tremors in Parkinson's disease and involuntary movements caused by certain antipsychotic medicines.

How does Tremnil-2 Tablet work?

The active ingredient, trihexyphenidyl, reduces the activity of a substance called acetylcholine that controls muscle contractions, helping to relax muscles and improve movement.

How should I take Tremnil-2 Tablet?

Tremnil-2 Tablet is taken orally with water, preferably with or after meals. Always remember to take your medicine at the same time each day.

What are the common side effects of Tremnil-2 Tablet?

Common side effects may include dry mouth, constipation, blurred vision, dizziness, and nausea. These can usually be managed by staying hydrated and eating a fibre-rich diet.

Are there any precautions I need to take while using Tremnil-2 Tablet?

If you have narrow-angle glaucoma, an enlarged prostate, blocked intestines, heart disease or kidney/liver problems, use Tremnil-2 Tablet with caution and consult your doctor.

Can I take other medications along with Tremnil-2 Tablet?

Certain medicines may interact with Tremnil-2 Tablet; it's important to inform your doctor about all the medications you're currently taking.

Is it safe to use Tremnil-2 Tablet during pregnancy or breastfeeding?

The safety of trihexyphenidyl during pregnancy isn't established and it's excreted in breast milk; thus consult your doctor before taking this medication if you're pregnant or breastfeeding.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

308-310, Dwarkesh Complex, Opp HCG Cancer Hospital, Sun Pharma Road, Atladra, Vadodara- 390 012 Gujarat, INDIA

Country of origin: INDIA

References

MedlinePlus. (n.d.). Trihexyphenidyl: MedlinePlus drug information. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a682160.html
U.S. Food and Drug Administration. (1998). Approval package for: ANDA 40184. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/anda/98/40184ap.pdf
Jilani, T. N., Sabir, S., Patel, P., & Sharma, S. (2024). Trihexyphenidyl. In StatPearls. StatPearls Publishing. Retrieved 15 October 2024, from https://www.ncbi.nlm.nih.gov/books/NBK519488/
Trihexyphenidyl. (n.d.). Retrieved 15 October 2024, from https://go.drugbank.com/drugs/DB00376
Trihexyphenidyl. (2012). In LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved 15 October 2024, from
https://pubmed.ncbi.nlm.nih.gov/31643310/

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