Trivolib 2 Tablet 15

Akums Drugs And Pharmacueticals Ltd

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MRP ~~₹355~~

₹284

₹23.67/Units

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Composition

Glimepiride (2 Mg) + Metformin (500 Mg) + Voglibose (0.2 Mg)

Trivolib 2 Tablet is primarily used to manage type 2 diabetes mellitus in adults. It is a combination medicine that belongs to the category of antidiabetic agents.

Besides managing diabetes, the medicine also helps reduce the risk of cardiovascular complications associated with diabetes, especially for patients with pre-existing cardiovascular disease. It provides a particularly beneficial role when diet, exercise, and a single antidiabetic medication are not sufficient enough to control blood sugar levels.

You must consult your doctor for the appropriate dosage and frequency of this medication. Remember to inform your doctor about any pre-existing conditions or ongoing medications before starting this medicine. If you experience any side effects while taking this medicine, let your doctor know immediately. To ensure the best results, continue taking the medicine for the duration prescribed by your doctor.

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Trivolib 2 Tablet is used for the following health conditions:

Managing type 2 diabetes mellitus in adults
Reducing the risk of cardiovascular complications, such as heart attacks or strokes

Directions for Use of Trivolib 2 Tablet 15

Swallow the tablet whole with a glass of water. Avoid breaking, chewing, or crushing it.
It's important to take the tablet at the same time each day to maintain consistent levels of medication in your body.
Remember to take this medicine with food; this can help avoid an upset stomach and improve absorption.
Keep taking the medicine even if you're feeling well.
Always take the medicine in the dosage and frequency prescribed by your doctor.

Trivolib 2 Tablet is taken orally.

Trivolib 2 Tablet may have the following common side effects:

Nausea and vomiting
Diarrhoea
Abdominal pain
Loss of appetite
Headache
Blurred vision
Hypoglycaemia: This is when your blood glucose levels become too low.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the medicine. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

You can also effectively manage common side effects like nausea, vomiting, diarrhoea, and abdominal pain at home by taking the medicine with or after your meals.

Trivolib 2 Tablet works in the human body in the following ways:

Glimepiride (2 mg): As a sulphonylurea, glimepiride stimulates the pancreas to produce more insulin, lowering blood sugar levels.
Voglibose (0.2 mg): It is an alpha-glucosidase inhibitor that inhibits the activity of the alpha-glucosidase enzyme, responsible for the conversion of carbohydrates into glucose. Voglibose, thus, decelerates this process, helping reduce post-meal spikes in blood sugar levels.
Metformin hydrochloride (500 mg): Metformin, a biguanide component, reduces liver-produced glucose, improves insulin sensitivity, and supports glucose uptake and utilisation by body tissues. It also slows down glucose absorption from the intestines.

Pregnancy

Trivolib 2 Tablet is contraindicated in pregnancy as it may cause harm to the foetus. Please consult your doctor if you're pregnant or planning to conceive before starting this medication.

Breastfeeding

The medicine is contraindicated while breastfeeding as the components of the tablet may pass into breast milk and affect the nursing infant. It's best to discuss with your doctor the potential risks and benefits of the medicine.

Alcohol

Avoid alcohol consumption while on this medication as it may result in hypoglycaemia (low blood glucose levels) and can also increase the risk of lactic acidosis (a condition where there is a buildup of lactic acid in your body).

Liver

This medicine is contraindicated in patients with severe liver disease as it may increase the risk of lactic acidosis. Always discuss your liver health with your doctor to understand potential risks.

Kidney

Trivolib 2 Tablet is also contraindicated in patients with severe kidney disease. Always consult your doctor before taking this medicine.

Using Machines & Driving

This medicine may cause side effects like blurred vision which could affect your ability to drive or operate machinery. If so, avoid such activities until these symptoms subside.

Allergy

The medicine is contraindicated if you're allergic to glimepiride, metformin hydrochloride, voglibose, or any other component of the tablet. Always discuss your allergies with your doctor.

Children

This medicine isn't recommended for children under 18 years of age. Always consult your doctor before giving any medication to a child.

Older Patients

Older patients, especially those with liver or kidney issues, should use the medicine under medical supervision as they may be more susceptible to its side effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Trivolib 2 Tablet may interact with the following medications:

Thiazide diuretics: Medicines like hydrochlorothiazide or indapamide when taken with the tablet might reduce the effectiveness of the medicine.
Corticosteroids: Medicines like prednisolone or dexamethasone can increase blood glucose levels, possibly reducing the effectiveness of the tablet.
Non-steroidal anti-inflammatory drugs (NSAIDs): The medicine may interact with NSAIDs like aspirin and ibuprofen and can further lower blood glucose levels.
Monoamine oxidase inhibitors (MAOIs): MAOIs like phenelzine and selegiline may potentiate the blood glucose-lowering effects of Trivolib 2 Tablet, causing adverse effects.
Anti-seizure medications: Medicines like phenytoin may increase blood glucose levels, potentially impacting the effectiveness of the tablet.

Drug-Food Interactions

Trivolib 2 Tablet may interact with certain foods, such as:

High-fat meals: Foods high in fats like dairy products, whole eggs, and fatty fish can reduce the effectiveness of the medicine.
Sodium-rich foods: Foods rich in sodium like processed cheese and seafood can increase the risk of cardiovascular diseases associated with diabetes.

Drug-Disease Interactions

Trivolib 2 Tablet may interact with the following diseases:

Type 1 diabetes: This medicine is contraindicated in patients with type 1 diabetes.
Diabetic ketoacidosis: Patients with diabetic ketoacidosis are contraindicated from taking this medicine.
Severe liver or kidney disease: People with severe liver or kidney disease are also contraindicated from using this medicine due to the risk of developing lactic acidosis.
Heart disease: Patients with heart disease may require careful monitoring when taking the medicine due to potential cardiovascular effects.

Daily Dose

Your doctor will prescribe the daily dose of Trivolib 2 Tablet. As this can differ based on individual factors, such as how severe your condition is and how you respond to the medicine, you must stick to this prescribed dosage.

Over Dose

If you accidentally take an overdose of the medicine, you may experience side effects such as low blood glucose levels, nausea, diarrhoea, or abdominal pain. If these symptoms persist or get worse, inform your doctor.

Missed Dose

If you forgot to take your medicine, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store the medicine at room temperature, below 30°C.
Keep it in a dry place, far away from heat and direct sunlight.
Ensure the medicine is kept out of reach of children.
Always remember to use this medicine before its expiry date.

Regular exercise can help your body use the insulin produced more effectively, thus aiding blood glucose control. Try including moderate physical activities like brisk walking or swimming in your daily routine.
Follow a balanced diet low in sugars and carbohydrates, as this could reduce the post-meal spike in blood sugar levels.

Fact Box

Drug Category	Sulphonylurea, Alpha-Glucosidase Inhibitor, Biguanide
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 diabetes mellitus

What is Trivolib 2 Tablet used for?

This medicine is used to manage type 2 diabetes mellitus in adults, especially when blood sugar levels are not properly controlled by diet, exercise, and single antidiabetic medicine.

How does Trivolib 2 Tablet work?

The medicine contains three active ingredients that work together to regulate blood sugar levels: glimepiride increases insulin production, metformin hydrochloride reduces glucose production, and voglibose slows down the conversion of carbohydrates into glucose.

How should I take Trivolib 2 Tablet?

You should take this medicine in the dosage and frequency prescribed by your doctor. The tablet should be swallowed whole and not crushed, chewed, or broken.

What are the common side effects of Trivolib 2 Tablet?

The common side effects of the medicine include hypoglycaemia, nausea, diarrhoea, abdominal pain, and loss of appetite. If these symptoms persist, consult your doctor.

Can I take Trivolib 2 Tablet if I have liver disease?

The medicine is contraindicated in patients with severe liver disease as it may increase the risk of lactic acidosis. Always consult your doctor before taking this tablet.

Can Trivolib 2 Tablet interact with other medicines?

Yes, it may interact with other antidiabetic medicines, thiazide diuretics, corticosteroids, NSAIDs, etc. Always inform your doctor about all the medications you're taking.

How should I store Trivolib 2 Tablet?

Store the tablet at room temperature, away from direct sunlight, heat, and moisture. Keep out of reach of children and dispose of expired medication properly.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Ashmita Borgohain

Medical Content Writer & Editor | 12 years

MSc (Applied Genetics)

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 3 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

PLOT NO 26 A 27 SECTOR 8 A IIF SIDCUL RANIPUR HARIDWAR 249403 UTTARAKHAND

Country of origin: INDIA

References

AMARYL. (n.d.). AMARYL (glimepiride tablets) 1, 2, and 4 mg. https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020496s021lbl.pdf
AstraZeneca. (2014). HIGHLIGHTS OF PRESCRIBING INFORMATION. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/205649s004lbl.pdf
Glimepiride: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB00222#
Voglibose: An Alpha Glucosidase Inhibitor. (2013, December 15). ncbi.nlm.nih.gov. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919386/
Corcoran, C., & Jacobs, T. F. (2023, August 17). Metformin. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK518983/
Kappe, C., Zhang, Q., Nyström, T., & Sjöholm, Å. (2014). Effects of high-fat diet and the anti-diabetic drug metformin on circulating GLP-1 and the relative number of intestinal L-cells. Diabetology & Metabolic Syndrome, 6(1). https://doi.org/10.1186/1758-5996-6-70

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