Verquvo 5 Mg Tablet 14

Verquvo 5mg Tablet 14

Bayer Zydus Pharma Pvt Ltd

Strip of 14 Units

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Composition

Vericiguat (5 Mg)

Strength:

5 MG 2.5 MG 10 MG

Verquvo 5mg Tablet is mainly used to manage chronic heart failure in adults, particularly those who have recently been hospitalised. This medicine is part of a group known as soluble guanylate cyclase (sGC) stimulators.

The primary purpose of this medication is to aid in the proper functioning of the heart by helping it pump blood more efficiently. It achieves this by relaxing the blood vessels, which in turn improves blood flow and reduces stress on the heart.

It's important to take this medicine as directed by your doctor, who will determine the right dosage and frequency for you based on your specific condition and overall health. Always inform your doctor about any other medications you're currently taking or any pre-existing conditions before starting Verquvo 5mg Tablet. If you notice any side effects while taking this medication, inform your doctor immediately. It's crucial to continue taking the medicine for the full duration prescribed by your doctor to ensure maximum benefit.

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Verquvo 5mg Tablet is employed for the following:

Management of symptomatic chronic heart failure in adults.
Use in adults who have recently been hospitalised due to heart failure.
Improving blood flow and heart function by relaxing the blood vessels in the lungs.
Reduction of the potential risk of hospitalisation or death from heart failure.

Directions for Use of Verquvo 5mg Tablet 14

Swallow the tablet whole with a glass of water.
Avoid crushing or chewing the tablet.
Take this medicine strictly as per your doctor's advice.
If you have difficulty swallowing the tablet whole, it can be crushed and mixed with water immediately before use. Remember to swallow this mixture straight away without chewing.
Consult your doctor prior to altering the dosage or stopping this medicine.

Verquvo 5mg Tablet is taken orally.

While taking Verquvo 5mg Tablet, you might experience the following side effects:

Anaemia: This could result in symptoms like unusual tiredness, feeling light-headed, and cold hands and feet.
Breathing problems
Rapid Heartbeat
Swelling of Face or Throat
Skin Rash

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Verquvo 5mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are simple ways to manage a couple common side effects:

Rapid Heartbeat: Practice deep breathing exercises and avoid stimulants like caffeine to help calm a rapid heartbeat.
Skin Rash: Apply a cool compress and use a gentle moisturizer to soothe the affected area.

Verquvo 5mg Tablet contains vericiguat (5 mg), which works on the body as follows:

Stimulates Soluble Guanylate Cyclase (sGC): Vericiguat stimulates an enzyme called soluble guanylate cyclase (sGC) in your body. This enzyme is responsible for making cyclic guanosine monophosphate (cGMP), a substance that helps control the tone of your blood vessels and how much blood they can carry.
Promotes Vasodilation: By increasing levels of cGMP, vericiguat helps to relax and widen your blood vessels a process known as vasodilation. This makes it easier for blood to flow through them, reducing the workload on your heart and improving its function.

Pregnancy

Verquvo 5mg Tablet is contraindicated during pregnancy. If you are pregnant or planning to conceive, make sure to discuss this with your doctor before starting this medicine.

Breastfeeding

Breastfeeding should be avoided while taking Verquvo 5mg Tablet. Consult your doctor to understand the potential risks and benefits.

Alcohol

While there's no specific caution against drinking alcohol while taking Verquvo 5mg Tablet, it's always a good idea to discuss your alcohol intake with your doctor before starting on any new medication.

Liver

Caution is advised while taking Verquvo 5mg Tablet if you have liver problems. Discuss them with your doctor before starting this medicine.

Kidney

If you have a history of any kidney problems, it is advisable to consult your doctor before using Verquvo 5mg Tablet.

Using Machines & Driving

Verquvo 5mg Tablet may affect your ability to drive or operate machinery. If you feel dizzy or unwell after taking the medicine, avoid these activities and speak to your doctor.

Allergy

If you are allergic to vericiguat or any other ingredients in Verquvo 5mg Tablet, avoid using this medicine. Always inform your doctor about any known allergies before starting a new medication.

Children

Verquvo 5mg Tablet is intended for adult use only. It is not recommended for children under the age of 18.

Older Patients

Older patients should take Verquvo 5mg Tablet under medical supervision as they may be more susceptible to its effects. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Verquvo 5mg Tablet interacts with the following medicines:

Erectile Dysfunction Medicines: Medications such as sildenafil, tadalafil, vardenafil, and avanafil may interact with Verquvo 5mg Tablet. This interaction can potentially increase side effects or reduce the effectiveness of either medication.
Soluble Guanylate Cyclase Stimulators: These medicines, like riociguat, should not be used alongside Verquvo 5mg Tablet due to potential interactions.

Drug-Food Interactions

There are no specific food items known to interact with Verquvo 5mg Tablet.

Drug-Disease Interactions

Verquvo 5mg Tablet interacts with the following diseases:

Pregnancy: Verquvo is contraindicated in pregnant women due to the risk of birth defects. Women of reproductive potential should have a negative pregnancy test before starting Verquvo.

Daily Dose

The daily dose of Verquvo 5mg Tablet should be taken as directed by your doctor. This dosage can vary depending on factors like your health condition and how you respond to the medicine. Always stick to the prescribed dosage, and never adjust it without your doctor's guidance.

Over Dose

Taking more than the recommended dose of Verquvo 5mg Tablet may lead to an increased risk of side effects such as unusual tiredness or light-headedness. If you suspect you've taken too much, let your doctor know as soon as possible.

Missed Dose

If you forget to take your scheduled dose of Verquvo 5mg Tablet, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your normal schedule. Always avoid doubling up on doses without consulting your doctor.

Store your Verquvo 5mg Tablet in a cool and dry place.
The ideal temperature for storage is below 30°C.
Avoid exposure to excessive light or moisture.
Always keep this medicine out of the reach of children.
Remember to use Verquvo 5mg Tablet before its expiry date.

If you're managing chronic heart failure with Verquvo 5mg Tablet, consider reducing your salt intake. Excessive sodium can make your heart work harder and exacerbate heart failure symptoms.
Regular, moderate physical activity can help you manage heart failure. However, it's essential to consult your doctor about the right type and amount of exercise that's safe for you.

Fact Box

Drug Category	Soluble Guanylate Cyclase Stimulator
Therapeutic Category	Heart Failure Medicine
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Chronic Heart Failure

What Is Verquvo 5mg Tablet Used For?

Verquvo 5mg Tablet is used to manage chronic heart failure in adults, specifically those who've recently been hospitalised due to heart failure.

How Does Verquvo 5mg Tablet Work?

The medicine works by stimulating an enzyme that helps relax blood vessels, thus improving blood flow and reducing the heart's workload.

How Should Verquvo 5mg Tablet Be Taken?

Verquvo 5mg Tablet is taken orally with food. If swallowing is difficult, it can be crushed and mixed with water immediately before consumption.

What Are the Side Effects of Verquvo 5mg Tablet?

The main side effect is anaemia, causing symptoms like pale skin and tiredness. More serious, but less common effects can include severe allergic reactions.

Can Verquvo 5mg Tablet Be Taken During Pregnancy?

No, Verquvo 5mg Tablet shouldn't be taken during pregnancy due to the risk of birth defects. Women of reproductive potential should use effective contraception during treatment.

Are There Any Drug Interactions With Verquvo 5mg Tablet?

Yes, medications for erectile dysfunction like sildenafil or tadalafil may interact with Verquvo 5mg Tablet. You should inform your doctor about any medicines you're taking.

How Should Verquvo 5mg Tablet Be Stored?

The tablets should be stored at room temperature, in a cool, dry place and out of reach of children.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

Bayer House, Central Avenue, Hiranandani Estate, Thane (west) Thane 400607 India

Country of origin: INDIA

References

Merck Sharp & Dohme Corp. (2021). HIGHLIGHTS OF PRESCRIBING INFORMATION [Press release]. https://www.accessdata.fda.gov/drugsatfda_docs/label/2021/214377s000lbl.pdf
Chiles, R., & Al-Horani, R. A. (2022). Vericiguat: a new hope for heart failure patients. Cardiovascular Therapeutics, 2022, 1–6. https://doi.org/10.1155/2022/1554875
Khan, M. S., Xu, H., Fonarow, G. C., Lautsch, D., Hilkert, R., Allen, L. A., DeVore, A. D., Alhanti, B., Yancy, C. W., Albert, N. M., Butler, J., & Greene, S. J. (2023). Applicability of Vericiguat to patients hospitalized for heart failure in the United States. JACC. Heart Failure, 11(2), 211–223. https://doi.org/10.1016/j.jchf.2022.11.007
Vericiguat: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB15456

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