Xarelto 25 Mg Tablet 14

Xarelto 2.5mg Tablet 14

Bayer Pharmaceuticals Pvt. Ltd.

Strip of 14 Units

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Composition

Rivaroxaban (2.5 Mg)

Strength:

20 MG 2.5 MG

Xarelto 2.5mg Tablet is primarily prescribed to prevent atherothrombotic events in adults following an acute coronary syndrome (ACS). This medicine is part of a group of medications known as anticoagulants.

This medicine also helps prevent venous thromboembolism (VTE) in patients undergoing hip or knee replacement surgery. By reducing the formation of blood clots, it can lower the risk of severe health problems such as deep vein thrombosis (DVT) and pulmonary embolism (PE).

Before starting this medicine, it's important to consult your doctor to discuss your medical history and any ongoing medications. Inform your doctor immediately if you notice any side effects while taking this medicine. For optimal results, make sure you continue taking the medicine for the duration prescribed by your doctor.

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Xarelto 2.5mg Tablet is used for the following:

Reducing the risk of heart attack and stroke in patients with specific cardiovascular conditions
Preventing atherothrombotic events in adults after acute coronary syndrome (ACS)
Acting in combination with aspirin alone or aspirin plus clopidogrel to prevent blood clots in arteries
Lowering the risk of deep vein thrombosis (DVT) and pulmonary embolism (PE) in patients undergoing knee or hip replacement surgery

Directions for Use of Xarelto 2.5mg Tablet 14

Swallow the tablet whole with a glass of water.
If you cannot swallow the tablet whole, it may be crushed and mixed with water or applesauce immediately before use.
Avoid taking more than the recommended dose without consulting your doctor.
Always remember not to stop using this medicine without first consulting your doctor.

Xarelto 2.5mg Tablet is taken orally.

Xarelto 2.5mg Tablet may have the following side effects:

Bleeding: This is a common side effect that results in blood loss from the body.
Peripheral oedema: Swelling in your limbs caused by fluid build-up.
Dizziness
Headache
Abnormal liver function

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Xarelto 2.5mg Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Bleeding: If you notice signs of bleeding, such as unusual bruising or blood in your urine or stools, stop taking Xarelto 2.5mg Tablet and seek immediate medical attention.
Peripheral oedema: If you notice swelling in your limbs, try elevating them when resting and avoid standing for long periods.

Xarelto 2.5mg Tablet contains rivaroxaban (2.5 mg), which operates in the body through the following mechanisms:

Factor Xa Inhibition: Rivaroxaban works by selectively inhibiting a key enzyme called factor Xa in your body. This enzyme plays a crucial role in blood clot formation.
Decreased Thrombin Generation: By inhibiting factor Xa, rivaroxaban effectively reduces the generation of thrombin, a protein that helps blood to clot.
Reduced Blood Clot Formation: The overall effect of these actions is to reduce the formation of blood clots in both veins and arteries, without directly affecting platelet aggregation, which are cells that help your blood clot.
Predictable Pharmacokinetics: Rivaroxaban demonstrates predictable pharmacokinetics, meaning the way the medicine is absorbed, distributed, metabolised and excreted in the body is consistent and predictable. This allows for fixed oral dosing without the need for routine coagulation monitoring.

Pregnancy

Xarelto 2.5mg Tablet should be avoided during pregnancy due to the risk of bleeding in the mother and fetus. If you are pregnant or planning to conceive, consult your doctor before using this medicine.

Breastfeeding

This medicine should not be used while breastfeeding. It could potentially cause serious adverse reactions in nursing infants. If you are breastfeeding, it's crucial to discuss this with your doctor.

Alcohol

Caution is advised when consuming alcohol while taking Xarelto 2.5mg Tablet, as it may enhance the effect of the medication and increase the risk of bleeding.

Liver

If you have liver problems, discuss them with your doctor before starting Xarelto 2.5mg Tablet. This medicine may affect liver function and should be used with caution in patients with mild to moderate liver impairment.

Kidney

Exercise caution if you have a history of kidney problems. Xarelto 2.5mg Tablet should be used carefully in patients with severe renal impairment and is not recommended for those with extremely low levels of renal functioning.

Using Machines & Driving

No specific precautions are known regarding driving or operating machinery while taking this medicine, but if you feel dizzy or faint, avoid such activities until you feel better.

Allergy

Xarelto 2.5mg Tablet is contraindicated if you have severe hypersensitivity reactions to rivaroxaban. Consult your doctor if you know or suspect that you may be allergic to any of its ingredients.

Children

Caution is advised while giving Xarelto 2.5mg Tablet to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take this medicine under medical supervision, as they may be more susceptible to its side effects. Your doctor will guide you based on your health status, especially if you are above 70 years of age and have liver or kidney issues.

Drug-Drug Interactions

Xarelto 2.5mg Tablet interacts with the following medicines:

Strong CYP3A4 Inhibitors: Medicines like ketoconazole and ritonavir may interact with Xarelto 2.5mg Tablet, potentially increasing the levels of rivaroxaban in your body.
Moderate CYP3A4 Inhibitors: Medicine like erythromycin and diltiazem, when taken with Xarelto 2.5mg Tablet, can lead to slightly higher levels of rivaroxaban.
Strong CYP3A4 Inducers: Medicines like carbamazepine, phenytoin, and St. John's wort may reduce the effectiveness of Xarelto 2.5mg Tablet by decreasing its exposure.

Drug-Food Interactions

Certain foods can interact with Xarelto 2.5mg Tablet:

Grapefruit Juice: This can increase the levels of rivaroxaban in your body, so it's best avoided while on this medication.

Drug-Disease Interactions

Xarelto 2.5mg Tablet interacts with the following diseases:

Bleeding Disorders: If you have a history of bleeding disorders, Xarelto 2.5mg Tablet could increase your risk of bleeding further.
Severe Hypertension: If you have uncontrolled high blood pressure, this medicine might elevate your risk of bleeding.
Ulcerative Gastrointestinal Disease: Patients with active ulcerative gastrointestinal disease might face an increased risk of gastrointestinal bleeding with this medicine.
Renal Impairment: Patients with severe renal impairment should use Xarelto 2.5mg Tablet cautiously as it can increase exposure to rivaroxaban.

Daily Dose

Your doctor will determine the daily dose of Xarelto 2.5mg Tablet. This depends on your health factors and how you respond to the medicine. Always stick to the prescribed dosage.

Over Dose

If you accidentally take too much Xarelto 2.5mg Tablet, you might experience symptoms like dizziness and headaches. If these symptoms persist or worsen, inform your doctor promptly.

Missed Dose

If you forget to take your Xarelto 2.5mg Tablet, take it as soon as you remember. If it's nearly time for your next dose, leave out the missed one and continue your regular schedule. Never alter your dosage without consulting your doctor.

Store Xarelto 2.5mg Tablet at room temperature, ideally between 20°C and 25°C.
Protect the medicine from moisture and excessive heat.
Keep the tablet in its original bottle to ensure its quality.
Ensure the cap is securely replaced after each opening.
Keep out of reach of children.
Use before the expiry date printed on the package.

If you're taking Xarelto 2.5mg Tablet due to a heart-related issue, try to maintain a low-fat diet. This helps in managing your condition by reducing cholesterol levels which can contribute to heart disease.
Regular, gentle exercise like walking or swimming can help improve circulation, reducing the risk of blood clots. Remember, consult your doctor before starting any new exercise programme.

Fact Box

Drug Category	Factor Xa Inhibitor
Therapeutic Category	Anticoagulant
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Acute Coronary Syndrome, Venous Thromboembolism

What is Xarelto 2.5mg Tablet used for?

Xarelto 2.5mg Tablet is used, along with aspirin, to prevent heart attacks, strokes and cardiovascular death in high-risk patients after an acute coronary event.

How does Xarelto 2.5mg Tablet work?

Xarelto contains rivaroxaban which inhibits factor Xa, a key enzyme in clot formation. This reduces the risk of blood clot formation in arteries and veins.

Can Xarelto 2.5mg Tablet be taken with food?

You must take the medicine as directed by your doctor.

What are the side effects of Xarelto 2.5mg Tablet?

Common side effects include bleeding, peripheral oedema (swelling), dizziness, headache, and abnormal liver function tests. Consult your doctor if these persist or worsen.

Are there any precautions to take while using Xarelto 2.5mg Tablet?

Avoid using Xarelto if you have active bleeding or severe hypersensitivity to rivaroxaban. Caution is advised in patients with high bleeding risk or severe renal impairment.

Can I use other medicines while taking Xarelto 2.5mg Tablet?

Certain medicines can interact with Xarelto affecting its efficacy and safety. Always consult your doctor before starting any new medication whilst on Xarelto.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

7238+35P, Digvijay Cooperative Housing Society, Kalher, Bhiwandi, Maharashtra 421302

Country of origin: INDIA

References

U.S. Food and Drug Administration. (2011). Clinical Pharmacology and Biopharmaceutics Review(s). Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/nda/2011/022406orig1s000clinpharmr.pdf
Rivaroxaban. (n.d.). Retrieved 13 October 2024, from
https://go.drugbank.com/drugs/DB06228
Rivaroxaban: Medlineplus drug information. (n.d.). Retrieved 13 October 2024, from
https://medlineplus.gov/druginfo/meds/a611049.html
Singh, R., & Emmady, P. D. (2024). Rivaroxaban. In StatPearls. StatPearls Publishing. Retrieved 13 October 2024, from
https://www.ncbi.nlm.nih.gov/books/NBK557502/
Rivaroxaban. (2012). In LiverTox: Clinical and Research Information on Drug-Induced Liver Injury. National Institute of Diabetes and Digestive and Kidney Diseases. Retrieved 13 October 2024, from
https://www.ncbi.nlm.nih.gov/books/NBK548015/

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