Zen Retard 400 Mg Tablet Er 10

Zen Retard 400 Tablet 10

Intas Pharmaceuticals Ltd

Strip of 10 Units

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MRP ~~₹52.19~~

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₹5.22/Units

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Composition

Carbamazepine (400 Mg)

Strength:

400 MG 300 MG

Zen Retard-400 Tablet is primarily employed to manage certain types of seizures in individuals with epilepsy. This medicine is part of a group of medications known as anticonvulsants.

In addition to managing seizures, this medicine is also used to alleviate the severe pain associated with trigeminal neuralgia, a chronic condition affecting the trigeminal nerve in the face.

Before starting on this medicine, it is vital to consult your doctor who will guide you on the appropriate dosage and frequency. Make sure to inform your doctor of any pre-existing conditions or ongoing medications. If you notice any side effects while on this medication, notify your doctor immediately. It's important to continue taking the medicine for the duration prescribed by your doctor for optimal results.

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Zen Retard-400 Tablet is used for the following:

Managing epilepsy: This medication aids in controlling certain types of seizures, including partial seizures, generalized tonic-clonic seizures, and mixed seizure patterns.
Alleviating trigeminal neuralgia pain: Zen Retard-400 Tablet helps reduce severe pain associated with this chronic condition affecting the facial nerve.

Directions for Use of Zen Retard 400 Tablet 10

Follow these instructions while taking Zen Retard-400 Tablet:

Swallow the tablet whole with a glass of water.
Avoid chewing, crushing or breaking the tablet.
For specific advice, consult your doctor.

Zen Retard-400 Tablet is taken orally.

Side Effects of Zen Retard 400 Tablet 10

You may experience the following side effects when taking Zen Retard-400 Tablet:

Dizziness
Fatigue
Nausea and vomiting
Constipation
Dry mouth
Blurred vision
Headache
Mild skin rash

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Zen Retard-400 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage common side effects:

Nausea and vomiting: Take Zen Retard-400 Tablet with food.
Constipation: Consider taking this medicine with plenty of water to increase hydration.

Zen Retard-400 Tablet contains carbamazepine (400 mg), which acts in the following ways:

Stabilises Nerve Membranes: Carbamazepine acts by stabilising the hyperexcited nerve membranes in your body. This action helps to manage and prevent seizures in people with epilepsy.
Inhibits Neuronal Firing: Alongside stabilising nerve membranes, carbamazepine also inhibits repetitive neuronal firing, further assisting in the control of seizures.
Reduces Synaptic Impulses: By reducing the spread of synaptic impulses, carbamazepine aids in controlling the spread of seizure activity.
Controls Pain Transmission: In cases of trigeminal neuralgia, carbamazepine manages the severe pain by inhibiting the transmission of pain signals through the trigeminal nerve.

Pregnancy

Zen Retard-400 Tablet should be used during pregnancy only if the potential benefit justifies the potential risk to the unborn baby. Always consult your doctor before taking this medicine if you are pregnant.

Breastfeeding

This medicine can pass into your breast milk, hence breastfeeding mothers should consult their doctor before using Zen Retard-400 Tablet.

Alcohol

Interaction with alcohol can affect how Zen Retard-400 Tablet works. If you drink alcohol, it is advisable to discuss this with your doctor before starting this medicine.

Liver

Caution is advised when taking Zen Retard-400 Tablet if you have liver problems. This medicine may affect liver function. Discuss your liver health with your doctor before starting this medicine.

Kidney

If you have a history of kidney problems, use Zen Retard-400 Tablet with caution. It is best to consult your doctor before starting this medicine.

Using Machines & Driving

Zen Retard-400 Tablet may cause dizziness, drowsiness, and fatigue which could affect your ability to drive or operate machinery. Be sure to understand how the medicine affects you before engaging in such activities.

Allergy

Do not take Zen Retard-400 Tablet if you're allergic to carbamazepine or any of the other ingredients in this medicine. Consult your doctor for alternatives if you have known allergies.

Children

Zen Retard-400 Tablet is meant for adult use. It should not be given to children under 18 years of age without medical supervision.

Older Patients

Older patients should take Zen Retard-400 Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised especially if patients are above 70 years of age as they might also have liver and kidney issues and might be on other medication. Your doctor will guide you based on your health status.

Interactions of Zen Retard 400 Tablet 10

Drug-Drug Interactions

Zen Retard-400 Tablet interacts with the following medicines:

Other Anticonvulsants: Medicines like phenytoin and valproic acid may interact with Zen Retard-400 Tablet, potentially altering its effectiveness in controlling seizures.
Antibiotics: Some antibiotics, such as erythromycin and clarithromycin, can affect how Zen Retard-400 Tablet works, possibly making it less effective.
Antifungals: If you take antifungal medicines like ketoconazole or itraconazole alongside Zen Retard-400 Tablet, the interaction may increase your risk of side effects.
Antidepressants: Certain antidepressants, like fluoxetine and fluvoxamine, can interfere with Zen Retard-400 Tablet, potentially leading to altered medicinal effects.
Calcium Channel Blockers: Medicines like diltiazem and verapamil may interact with Zen Retard-400 Tablet, potentially increasing the risk of side effects.
Hormonal Contraceptives: Zen Retard-400 Tablet can reduce the effectiveness of hormonal contraceptives, so you may need to use additional methods of contraception.

Drug-Food Interactions

Drug-Disease Interactions

Zen Retard-400 Tablet interacts with the following diseases:

Bone Marrow Depression: If you have a history of bone marrow depression, taking Zen Retard-400 Tablet could worsen your condition.
Liver or Kidney Impairment: Caution is advised if you have liver or kidney issues as this medicine could potentially exacerbate these conditions.
Cardiac Conduction Disturbances: For individuals with heart rhythm problems, Zen Retard-400 Tablet might cause complications due to its potential effect on cardiac conduction.
Increased Intraocular Pressure: If you have high eye pressure, Zen Retard-400 Tablet should be used carefully as it could potentially increase the pressure further.

Daily Dose

Your doctor will prescribe the daily dose of Zen Retard-400 Tablet. The dosage depends on your condition and how you respond to the medicine. Always follow your doctor's instructions.

Over Dose

Overdosing on Zen Retard-400 Tablet may cause drowsiness and nausea. If you think you've taken too much, don't panic but do inform your doctor about it.

Missed Dose

If you miss a dose of Zen Retard-400 Tablet, take it as soon as possible. However, if it's close to time for the next dose, skip the missed one.

Ensure Zen Retard-400 Tablet is stored at room temperature, between 15 and 30°C.
Keep the tablet in its original packaging to protect it from light and moisture.
Place the medicine in a secure location, out of reach of children.
Always check the expiry date and avoid using the tablet if it has expired.

If you're taking Zen Retard-400 Tablet for epilepsy, try maintaining a well-balanced diet. Certain foods like whole grains, fruits, vegetables, and lean protein can help manage your condition.
If you're using this medication for trigeminal neuralgia, consider keeping your stress levels low. Stress might trigger pain episodes. Mindful activities such as yoga or meditation may help you manage this. Please consult your doctor for personalised advice.

Fact Box

Drug Category	Anticonvulsant
Therapeutic Category	Anti-epileptic
Available Dosage Types	Tablet ER
Habit Forming	No
Ailment	Epilepsy, Trigeminal Neuralgia

What is Zen Retard-400 Tablet used for?

The medicine is used to manage epilepsy and trigeminal neuralgia, a condition causing severe facial pain.

How does Zen Retard-400 Tablet work?

It calms overactive nerves, reducing seizures in epilepsy and pain in trigeminal neuralgia.

How should I take Zen Retard-400 Tablet?

You must take the medicine as directed by your doctor.

What are the common side effects of Zen Retard-400 Tablet?

Common side effects include dizziness, fatigue, nausea, dry mouth, and mild skin rash.

Can I take other medicines with Zen Retard-400 Tablet?

Carbamazepine can interact with many medicines. Always inform your doctor about all other medications you are taking.

Can pregnant or breastfeeding women use Zen Retard-400 Tablet?

Only use if potential benefits outweigh risks to the baby. Consult your doctor before using.

How should I store Zen Retard-400 Tablet?

Store at room temperature (15-30°C) in a closed container away from light and moisture.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Corporate House, Near Sola Bridge, S. G. Highway, Thaltej, Ahmedabad 380054, Gujarat, India

Country of origin: INDIA

References

U.S. National Library of Medicine. (n.d.). DailyMed - CARBAMAZEPINE- carbamazepine tablet, chewable. DailyMed. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3a3344dc-9cc8-41da-859e-295d053597c1
U.S. Food and Drug Administration. (2015). Carbamazepine ER tab PSG. FDA. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/psg/Carbamazepine_ER%20tab_020234_RV03-15.pdf
Carbamazepine: Medicine to treat epilepsy and nerve pain. (2022, March 8). Nhs.Uk. Retrieved 24 October 2024, from
https://www.nhs.uk/medicines/carbamazepine/
Carbamazepine: Medlineplus drug information. (n.d.). Retrieved 24 October 2024, from https://medlineplus.gov/druginfo/meds/a682237.html
Carbamazepine. (n.d.). Retrieved 24 October 2024, from https://go.drugbank.com/drugs/DB00564

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