Zeptol Cr 400 Mg Tablet Pr 10

Zeptol Cr 400 Tablet 10

Sun Pharma Laboratories Ltd.

Strip of 10 Units

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MRP ~~₹52.19~~

₹42.8

₹5.22/Units

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Composition

Carbamazepine (400 Mg)

Strength:

300 MG 200 MG 400 MG

Zeptol CR 400 Tablet is primarily used to manage certain types of seizures associated with epilepsy. This medicine belongs to a class of medications known as anticonvulsants.

In addition to managing epilepsy, this tablet is also used to alleviate the facial nerve pain caused by a condition known as trigeminal neuralgia. It has been found to be particularly effective in patients over 50.

Before taking this medicine, you should consult your doctor, who will advise you on the appropriate dosage and frequency. You must inform your doctor about any pre-existing conditions or ongoing medications that you may have. Contact your doctor immediately if you experience any side effects while using this medicine. Remember to continue taking the medicine for the duration prescribed by your doctor to ensure optimal results.

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Zeptol CR 400 Tablet is typically used for:

Management of partial seizures with complex symptomatology: This type of seizure begins in one part of the brain and can affect the person's consciousness.
Control of generalized tonic-clonic seizures: These are the most common type of generalised seizure, involving the whole body in a series of spasms and contractions.
Handling mixed seizure patterns: This refers to individuals who experience more than one type of seizure.
Relieving pain associated with trigeminal neuralgia: This condition causes severe facial pain that feels like a shock.

Directions for Use of Zeptol Cr 400 Tablet 10

To correctly use Zeptol CR 400 Tablet, please follow these steps:

Swallow the tablet whole with a glass of water. Do not chew or crush it, as this can interfere with the extended-release function, leading to rapid absorption.
You can take this medication with or without food, according to your preference.
For specific dose instructions, kindly consult your doctor.

Zeptol CR 400 Tablet is taken orally.

Using Zeptol CR 400 Tablet might lead to a few common side effects, such as:

Dizziness
Drowsiness
Unsteady movements: You may experience difficulty with coordinated movements.
Blurred vision
Dry mouth: Also known as xerostomia, this is when your mouth feels unusually dry.
Swelling: You might notice swelling in certain parts of your body. This is referred to as oedema.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve on discontinuing the use of Zeptol CR 400 Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips to manage a couple of common side effects:

Dizziness: Try taking Zeptol CR 400 Tablet at night, before going to bed.
Nausea: If you feel nauseous after taking this medicine, try having it with your meals.

Zeptol CR 400 Tablet contains carbamazepine (400 mg), which has several mechanisms of action:

Reducing Polysynaptic Responses: Carbamazepine helps in diminishing polysynaptic responses, which are reactions involving more than one synapse in the nervous system.
Blocking Post-Tetanic Potentiation: This involves impeding an increased level of neuronal excitability following a repetitive stimulation.
Depressing Thalamic Potential and Bulbar and Polysynaptic Reflexes: Carbamazepine can suppress these forms of activity in our nervous system, helping manage epileptic seizures.
Raising Synaptic Threshold: This means it increases the level at which neurons in the brain are activated, which can help reduce seizures.
Reducing Temporal Stimulation Summation: Carbamazepine decreases the build-up of activity over time in certain nerve pathways, which can help control seizures.

Pregnancy

Zeptol CR 400 Tablet may cause harm to the unborn child. If you're pregnant, caution is advised. It is best to consult your doctor before taking this medicine.

Breastfeeding

This medicine is secreted in breast milk. Weigh the benefits against risks and consult your doctor before using Zeptol CR 400 Tablet while breastfeeding.

Alcohol

It's advisable to limit alcohol consumption while taking this medicine as it may increase the risk of side effects or alter the medication's effectiveness.

Liver

If you have severe liver disease, using Zeptol CR 400 Tablet isn't recommended. Caution is advised in case of mild to moderate liver impairment. Discuss with your doctor if you've any liver problems before starting this medicine.

Kidney

Exercise caution while taking this medicine if you have kidney health issues. Consulting your doctor prior to its use is advisable.

Using Machines & Driving

Zeptol CR 400 Tablet may make you feel dizzy or drowsy, affecting your ability to drive or operate machinery. Exercise caution until you know how it affects you.

Allergy

This medicine is contraindicated if you're allergic to carbamazepine or any other components of Zeptol CR 400 Tablet. Inform your doctor about any previous allergic reactions to medicines.

Children

Children under 12 years should take this medicine under medical supervision. It's crucial to consult a doctor before giving Zeptol CR 400 Tablet to a child.

Older Patients

Older patients may be more susceptible to the side effects of Zeptol CR 400 Tablet. If you're above 70 years, take this medication under medical supervision. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Zeptol CR 400 Tablet may interact with the following medicines:

Macrolide antibiotics: Medications like erythromycin and clarithromycin may interact with Zeptol CR 400 Tablet, potentially increasing carbamazepine levels in your body.
Other antiepileptic medications: Medicines such as phenytoin and phenobarbital can interact with Zeptol CR 400 Tablet, potentially decreasing the levels of carbamazepine in your bloodstream.
Oral contraceptives: Zeptol CR 400 Tablet can reduce the effectiveness of oral contraceptives due to its ability to induce the enzyme CYP3A4.
Immunosuppressants: Cyclosporine levels may be decreased when used alongside Zeptol CR 400 Tablet due to induction of the enzyme CYP3A4.
Anticoagulants: The medicine can also reduce the effectiveness of warfarin, an anticoagulant medication.

Drug-Food Interactions

Zeptol CR 400 Tablet could interact with grapefruit juice. Below is a known interaction:

Grapefruit Juice: Consuming grapefruit juice while taking Zeptol CR 400 Tablet may increase carbamazepine levels in your body.

Drug-Disease Interactions

Zeptol CR 400 Tablet may interact with the following diseases:

Liver Disease: Individuals with severe liver disease should use Zeptol CR 400 Tablet cautiously as it could exacerbate their condition.
Kidney Disease: Due to potential adverse effects, the medicine should be used with caution in patients with severe kidney disease.
Cardiac Disorders: People with a history of cardiac conduction disturbances should take this medication cautiously.

Daily Dose

The daily dosage of Zeptol CR 400 Tablet should be taken as directed by your doctor. The dose can change based on individual factors such as your health condition and response to the medicine. Sticking to the prescribed dosage and not increasing it without your doctor's advice is vital. For further details, read the package insert.

Over Dose

Overdose symptoms may include dizziness, unsteadiness, drowsiness, nausea, and vomiting. Contact your doctor for guidance if you've taken more than the recommended dose and experience these symptoms.

Missed Dose

If you forget to take your Zeptol CR 400 Tablet at the scheduled time, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue your regular schedule. Don't double up on doses. Always consult your doctor if you're unsure.

Store your Zeptol CR 400 Tablet at room temperature.
Keep it away from direct light and moisture.
Ensure the medicine is kept out of reach and sight of children.
Remember to use it before the expiry date printed on the pack.

If you have epilepsy, try to maintain a regular sleep schedule. Disrupted sleep patterns can sometimes trigger seizures.
For those dealing with trigeminal neuralgia, avoid consuming very cold or hot food and beverages, as extreme temperatures may trigger facial pain.

Fact Box

Drug Category	Anticonvulsant
Therapeutic Category	Antiepileptic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Epilepsy, Trigeminal Neuralgia

What is Zeptol CR 400 Tablet used for?

Zeptol CR 400 Tablet is an anticonvulsant medication that helps manage certain types of seizures in epilepsy and pain associated with trigeminal neuralgia.

How does Zeptol CR 400 Tablet work?

Zeptol CR 400 Tablet contains carbamazepine, which reduces synaptic activity and blocks post-tetanic potentiation, likely helping control seizures and relieve pain.

Can I take this medicine with food?

Yes, you can take Zeptol CR 400 Tablet with or without food. Remember not to chew or crush the tablet; swallow it whole.

What are the common side effects of Zeptol CR 400 Tablet?

Common side effects include dizziness, drowsiness, unsteadiness, nausea, vomiting, blurred vision, headache, dry mouth, and swelling.

Can I take Zeptol CR 400 Tablet if I'm pregnant?

Carbamazepine in Zeptol CR 400 Tablet can harm the foetus. If you're pregnant or planning to conceive, consult your doctor before taking this medicine.

Can Zeptol CR 400 Tablet interact with other medicines?

Yes. It interacts with medicines metabolised by CYP3A4 enzyme like oral contraceptives and warfarin. Always consult your doctor before starting any new medication.

What should I do if I overdose on Zeptol CR 400 Tablet?

Overdose can result in dizziness, nausea, and even coma. If you suspect an overdose, seek immediate medical attention.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Meenakshi Maruwada

Medical Content Writer & Strategist | 8 years

BDS, PGCAD, GMHE (IIM-B)

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

DailyMed. (n.d.). CARBAMAZEPINE carbamazepine tablet. Retrieved 1 April 2024, from https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3a3344dc-9cc8-41da-859e-295d053597c1
WebMD. (n.d.). Carbamazepine Oral : Uses, Side Effects, Interactions, Pictures, Warnings & Dosing. Retrieved 1 April 2024, from https://www.webmd.com/drugs/2/drug-1493-5/carbamazepine-oral/carbamazepine-oral/details
U.S. Food and Drug Administration. (2015). CARBAMAZEPINE ER tablet. Retrieved 1 April 2024, from https://www.accessdata.fda.gov/drugsatfda_docs/psg/Carbamazepine_ER%20tab_020234_RV03-15.pdf

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