Zomelis 50 Mg Tablet 15

Zomelis 50mg Tablet 15

Eris Lifesciences Ltd

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Composition

Vildagliptin (50 Mg)

Zomelis Tablet is predominantly used to manage type 2 diabetes in adults. It's a part of the antidiabetic medication group, specifically known as dipeptidyl peptidase-4 (DPP-4) inhibitors.

Beyond its main use, this tablet can be used in combination with diet and exercise when single-antidiabetic therapy doesn't bring about sufficient control of blood sugar levels. It also teams up well with other antidiabetic medicines such as metformin, sulfonylurea, or thiazolidinedione. However, it's not recommended for managing type 1 diabetes or diabetic ketoacidosis.

Before starting this medicine, let your doctor know about any ongoing medications or pre-existing conditions you might have.

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Zomelis Tablet is beneficial in these health conditions:

Improving control of blood sugar levels in adults with type 2 diabetes mellitus
Serving as an additional therapy when diet and exercise alone do not provide adequate blood sugar control
Use in combination with other antidiabetic medicines like metformin, a sulfonylurea, or a thiazolidinedione, to enhance glucose control

Directions for Use of Zomelis 50mg Tablet 15

Here's how to take Zomelis Tablet properly:

Swallow the tablet whole, without crushing or chewing it.
You can take the medicine with or without food.
Always drink a glass of water while taking this tablet.
If you forget a dose, take it as soon as you remember. But if it's nearly time for your next dose, skip the missed one. Never take two doses at once.
For any specific advice on how to use this medicine, consult your doctor.

Zomelis Tablet is taken orally.

Zomelis Tablet may have the following common side effects:

Nasopharyngitis: This refers to the common cold, which includes symptoms like a runny nose, sore throat, and cough.
Headache
Tremor
Dizziness
Fatigue
Nausea
Peripheral Edema: This means swelling in your hands, feet, or ankles.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolves on discontinuing the use of Zomelis Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Hypoglycemia: Try taking Zomelis Tablet with your meals to reduce the chance of your blood sugar dropping too low.
Nausea: If you feel nauseous after taking this medicine, you can try taking it after meals to lessen this effect.

Zomelis Tablet contains Vildagliptin (50 mg). The working process of this medicine includes:

DPP-4 Inhibition: Vildagliptin acts by blocking the enzyme DPP-4. This enzyme is responsible for breaking down incretin hormones GLP-1 and GIP which are released by our intestine.
Increased Incretin Hormones Action: By inhibiting DPP-4, Vildagliptin increases and prolongs the actions of incretin hormones. This results in more insulin being released when there is glucose in your body and reducing levels of glucagon.

Pregnancy

Zomelis Tablet is not recommended for use during pregnancy unless clearly necessary. If you are pregnant or planning to conceive, ensure to discuss this with your doctor before starting this medicine.

Breastfeeding

Zomelis Tablet should not be used while breastfeeding. Consult your doctor to understand the potential risks and benefits.

Alcohol

It's best to avoid alcohol while taking Zomelis Tablet as it can increase the risk of low blood sugar (hypoglycaemia) and may also worsen some side effects like dizziness and fatigue.

Liver

Caution is advised while taking Zomelis Tablet if you have any liver problems. This medicine may affect liver function, so discuss this with your doctor before starting the medication.

Kidney

For patients with moderate or severe kidney impairment, a lower dose of Zomelis Tablet is recommended. Make sure to consult your doctor if you have a history of kidney problems before taking this medicine.

Using Machines & Driving

Zomelis Tablet might cause dizziness as a side effect. If you experience dizziness after taking this medicine, avoid driving or operating heavy machinery until you feel well enough.

Allergy

If you're allergic to Vildagliptin or any other components in Zomelis Tablet, it's essential to inform your doctor before starting the medication.

Children

Zomelis Tablet has not been established for use in children under 18 years of age. Always consult with your doctor before giving this medicine to a child.

Older Patients

Older patients should take Zomelis Tablet under medical supervision as they may be more susceptible to its side effects, especially those with liver or kidney issues.

Drug-Drug Interactions

Zomelis Tablet interacts with the following medicines:

Sulfonylureas: When taken together with Zomelis Tablet, medications like glipizide or gliclazide may increase the risk of low blood sugar or hypoglycemia. It might be necessary to lower the dose of the sulfonylurea.
ACE inhibitors: If you're using medicines such as enalapril or lisinopril, it's advised to exercise caution when taking Zomelis Tablet. There could be an increased risk of swelling beneath the skin surface, known as angioedema, especially in patients with renal impairment.

Drug-Food Interactions

There are no specific food items that are known to interact with Zomelis Tablet. You can take it before or after meals.

Drug-Disease Interactions

Zomelis Tablet interacts with the following diseases:

Liver Disease: If you have a liver condition, it's important to monitor your liver function regularly when taking Zomelis Tablet. There have been rare cases of liver dysfunction associated with Vildagliptin.
Pancreatitis: Patients who have a history of inflammation of the pancreas should exercise caution when taking Zomelis Tablet. There's a risk of developing acute pancreatitis. If symptoms like severe abdominal pain occur, you should discontinue the medication and consult your doctor.

Daily Dose

The daily dose of Zomelis Tablet should be taken as instructed by your doctor. The specific dosage may vary based on individual factors such as the severity of your condition and how you respond to the medicine. It's crucial to adhere to the prescribed dosage and not exceed it without consulting your doctor.

Over Dose

An overdose of Zomelis Tablet might lead to some common side effects becoming more pronounced. If you suspect you've taken an extra dose, don't panic, but do inform your doctor, who can provide appropriate advice based on your symptoms.

Missed Dose

If you forget to take a dose of Zomelis Tablet, take it as soon as you remember. If it's nearly time for your next dose, skip the missed one and continue with your regular dosage schedule. Never try to compensate for a missed dose by taking extra medication without consulting your doctor.

Store Zomelis Tablet in its original package to shield it from moisture.
Keep the medicine at room temperature, ideally between 10°C and 25°C.
Try to store Zomelis Tablet in a dry and dark place.
Always keep this medication out of reach of children.
Make sure you use Zomelis Tablet before the expiry date printed on the package.

Regular physical activity can help manage blood sugar levels, so try to incorporate exercises into your daily routine. It's always beneficial for individuals with type 2 diabetes mellitus.
Monitor your diet carefully. Aim for a balanced intake that restricts high-sugar foods and beverages. This can go a long way in controlling your blood glucose levels, which is crucial when you're taking Zomelis Tablet.

Fact Box

Drug Category	DPP-4 Inhibitor
Therapeutic Category	Antidiabetic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Type 2 Diabetes

What is the main use of Zomelis Tablet?

Zomelis Tablet is used to manage blood sugar levels in adults with type 2 diabetes mellitus, alongside diet and exercise.

Can Zomelis Tablet be used for type 1 diabetes?

No, Zomelis Tablet is not indicated for managing type 1 diabetes or diabetic ketoacidosis. It's meant for type 2 diabetes.

How does Zomelis Tablet work in the body?

Zomelis Tablet works by increasing hormones that stimulate insulin release and reduce glucagon levels, thus regulating blood sugar.

Can I drink alcohol while taking Zomelis Tablet?

It's best to avoid alcohol as it can increase hypoglycemia risk and worsen side effects like dizziness and fatigue.

Will taking Zomelis Tablet lead to weight gain?

Vildagliptin, the active ingredient in Zomelis Tablet, does not cause significant weight gain or loss. It's considered weight-neutral.

When can I expect to see results after starting Zomelis Tablet?

Blood sugar control improvements can be seen within 2 weeks of starting Zomelis Tablet; the full effect may take up to 3 months.

Can I take other medicines while on Zomelis Tablet?

Yes, but always consult your doctor before starting any new medicine while taking Zomelis Tablet to avoid potential interactions.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

Shivarth Ambit, Plot No. 142/2, Ramdas Road, Off SBR, Near Swati Bungalows, Ahmedabad, Gujarat - 380054

Country of origin: INDIA

References

Bosi, E., Camisasca, R. P., Collober, C., Rochotte, E., & Garber, A. J. (2010). Effects of Vildagliptin on glucose control over 24 weeks in patients with type 2 diabetes inadequately controlled with metformin. Diabetes Care, 33(4), 822-827. Retrieved from https://pubmed.ncbi.nlm.nih.gov/20964454/. Accessed on 1 April 2024.
U.S. Food and Drug Administration. (2008). NDA 21-995 Galvus (Vildagliptin) Tablets. Retrieved from https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/021995s007lbl.pdf. Accessed on 1 April 2024.
Croxtall, J. D., & Keam, S. J. (2008). Vildagliptin: a review of its use in the management of type 2 diabetes mellitus. Drugs, 68(16), 2387–2409. https://doi.org/10.2165/0003495-200868160-00009

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