Zonegran 100 Mg Tablet 10

Zonegran Tablet 10

Eisai Pharmaceuticals India Ltd

Strip of 10 Units

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MRP ~~₹262~~

₹214.84

₹26.20/Units

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Composition

Zonisamide (100 Mg)

Zonegran Tablet is primarily used to manage epilepsy, specifically, partial seizures. This medicine falls under the category of anti-epileptic medications.

In addition to managing partial seizures, this medicine can also be used to control seizures affecting the entire brain, known as generalized seizures. It suppresses abnormal electrical activity in the brain, thereby preventing and controlling these seizures.

This medicine must be taken as directed by your doctor, who will consider your health condition and other factors to prescribe the appropriate dosage and frequency. It's important to inform your doctor of any health issues you have or any other medications you are currently taking. If you notice any side effects while on this medicine, let your doctor know immediately. Remember to take this medicine for the duration prescribed by your doctor for optimal results.

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Zonegran Tablet is used for the following:

Management of partial seizures in adults: These are seizures that affect only a part of the brain.
Control of generalized seizures in adults: Generalized seizures involve all areas of the brain.
As an adjunctive therapy along with other anti-epileptic medicines: This means Zonegran Tablet is used along with other medications to better manage epilepsy.

Directions for Use of Zonegran Tablet 10

Here's how you should take Zonegran Tablet:

Swallow the tablet whole with a glass of water. Avoid crushing or chewing it.
Do not exceed the dose recommended by your doctor.
It's crucial not to stop taking this medicine without first consulting your doctor.

Zonegran Tablet is taken orally.

The use of Zonegran Tablet may lead to the following side effects:

Drowsiness
Dizziness
Loss of appetite
Memory impairment
Nausea
Diarrhoea
Confusion
Difficulty in concentrating

Managing the Side Effects:

Most side effects are temporary and generally harmless, which are resolved by discontinuing the use of Zonegran Tablet. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor.

Here are some tips on managing common side effects:

Nausea: Try taking Zonegran Tablet with food to lessen this effect.
Drowsiness: Consider taking this medicine at night if it makes you sleepy during the day.

Zonegran Tablet contains Zonisamide (100mg) which acts on the body in the following ways:

Carbonic Anhydrase Inhibition: Zonisamide is a carbonic anhydrase inhibitor. This means it can reduce abnormal electrical discharges in the brain, which are the primary cause of seizures.
Neurotransmitter Effects: Zonisamide may also influence neurotransmitters like GABA, dopamine, and serotonin. These substances play a role in regulating the excitability of neurons, meaning that they control how often and how easily neurons fire. By affecting these neurotransmitters, zonisamide can help control and prevent seizures.

Pregnancy

Caution is advised while taking Zonegran Tablet if you are pregnant. It is best to consult your doctor before using this medicine.

Breastfeeding

Nursing mothers should take precautions while taking Zonegran Tablet. Consult your doctor to understand the potential risks and benefits.

Alcohol

It's advisable not to consume alcohol while on Zonegran Tablet, as it might enhance drowsiness and dizziness. Confirm with your doctor for detailed advice.

Liver

If you have a history of liver disease, exercise caution when taking Zonegran Tablet. Discuss your health concerns with your doctor before starting this medication.

Kidney

Caution is recommended for those with kidney health issues considering taking Zonegran Tablet. Consult your doctor before using this medication.

Using Machines & Driving

Zonegran Tablet may cause drowsiness or dizziness, affecting your ability to drive or operate machinery. Ensure you know how this medicine affects you before engaging in these activities.

Allergy

If you are allergic to zonisamide or any other sulfonamides, Zonegran Tablet is contraindicated. Make sure to discuss any known allergies with your doctor before starting this medicine.

Children

Zonegran Tablet should not be given to children under 16 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Zonegran Tablet under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are over 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Zonegran Tablet interacts with the following medicines:

Carbonic Anhydrase Inhibitors: Medications like acetazolamide may interact with Zonegran Tablet, potentially leading to increased side effects due to additive inhibitory effects on the enzyme carbonic anhydrase.
Opioids: Medicines such as morphine or codeine can interact with Zonegran Tablet, possibly intensifying drowsiness and mental confusion.
Antihistamines: Medicines like cetirizine or loratadine may interact with Zonegran Tablet, potentially enhancing sedative effects and causing dizziness or drowsiness.

Drug-Food Interactions

Drug-Disease Interactions

Zonegran Tablet interacts with the following diseases:

Kidney Disease: Individuals with kidney disease should use caution when taking Zonegran Tablet as it may increase the risk of kidney stone formation.
Liver Disease: Patients with liver disease need to be careful as this medicine could exacerbate their condition.
Lung or Breathing Problems: People with lung or breathing issues should exercise caution when using Zonegran Tablet as it may worsen their condition.
Mental Health Issues: Individuals with mental health problems need to be cautious because this medicine might trigger episodes of depression or suicidal thoughts.

Daily Dose

Your doctor will decide the daily dose of Zonegran Tablet considering factors such as your condition and response to the medicine. It's crucial to adhere to this prescribed dosage and not exceed it without your doctor's advice.

Over Dose

In case you accidentally take more Zonegran Tablet than prescribed, you might feel unusually drowsy or experience slow breathing. If you notice these symptoms, inform your doctor about the situation.

Missed Dose

If you forget to take your regular dose of Zonegran Tablet, take it as soon as you remember. However, if it's nearly time for the next dose, skip the missed one and continue with your regular schedule. Don't increase your dose without consulting your doctor.

Store your Zonegran Tablet at room temperature, ideally between 20°C and 25°C.
Protect it from light and moisture to maintain its efficacy.
Always keep this medicine out of the reach of children.
Ensure you use the medicine before its expiry date.

Since Zonegran Tablet is used to manage epilepsy, it's important to avoid triggers that may induce seizures. Certain food items, such as caffeine or alcohol, can be potential triggers. Try to limit your intake of these.
Regular exercise can be beneficial in managing epilepsy. However, make sure you do not overexert yourself as intense physical activities can sometimes trigger seizures. Always consult your doctor before starting any new exercise regimen.

Fact Box

Drug Category	Anticonvulsant, Carbonic Anhydrase Inhibitor
Therapeutic Category	Anti-epileptic
Available Dosage Types	Tablet
Habit Forming	No
Ailment	Partial Seizures, Generalized Seizures

What is Zonegran Tablet used for?

Zonegran Tablet helps to manage seizures in adults with epilepsy, specifically partial seizures that affect a part of the whole brain.

How does Zonegran Tablet work?

Zonegran Tablet reduces abnormal electrical activity in the brain, preventing seizures. The exact mechanism is unknown, but it likely impacts neurotransmitters.

How should I take Zonegran Tablet?

You must take the medicine as directed by your doctor.

What precautions should I take while using Zonegran Tablet?

Inform your doctor of any allergies, current medications, and health issues. The medicine should be used with caution if you have a history of kidney stones or liver disease.

What are the side effects of Zonegran Tablet?

Common side effects include drowsiness, dizziness, loss of appetite, nausea, and confusion. Less common but serious side effects can include allergic reactions and kidney stones.

Can Zonegran Tablet interact with other medicines?

Yes, Zonegran Tablet may interact with medicines such as carbonic anhydrase inhibitors, orlistat, antacids and medicines causing drowsiness. Discuss all medications with your doctor before use.

What should I do if I miss a dose of Zonegran Tablet?

Take the missed dose as soon as you remember unless it's near the time for the next dose. Do not take double doses to compensate.

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 7 years

BDS, MDS

Reviewed by

Dr. Osama Ahmed

Dental/Medical Writer, Editor, Reviewer | 2 years

Bachelor of Dental Surgery

Check out Editorial Policy

Manufacturer details

6th Floor, A Wing, Marwah Centre, Krishanlal Marwah Marg, Andheri East, Mumbai, Maharashtra 400072

Country of origin: INDIA

References

MedlinePlus. (n.d.). Zonisamide. Retrieved 1 April 2024, from https://medlineplus.gov/druginfo/meds/a603008.html
U.S. Food and Drug Administration. (2016). Zonisamide. Retrieved 1 April 2024, fromhttps://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020789s034lbl.pdf
Brodie, M. J., Ben-Menachem, E., Chouette, I., & Giorgi, L. (2012). Zonisamide: its pharmacology, efficacy and safety in clinical trials. Acta neurologica Scandinavica. Supplementum, (194), 19–28. https://doi.org/10.1111/ane.12016
Kadian R, Kumar A. Zonisamide. [Updated 2023 May 16]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK507903/
Leppik I. E. (2004). Zonisamide: chemistry, mechanism of action, and pharmacokinetics. Seizure, 13 Suppl 1, S5–S10. https://doi.org/10.1016/j.seizure.2004.04.016

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