Zonisep 25 Capsule 10

Sun Pharma Laboratories Ltd.

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Composition

Zonisamide (25 Mg)

Strength:

50 MG 100 MG 25 MG

Zonisep 25 Capsule is primarily used for managing partial seizures in adults. It belongs to a group of medicines known as antiepileptic medicines.

This medicine can be used alone or in combination with other antiepileptic medicines. It may be used for conditions like Parkinson's disease.

Before you start taking this medicine, it is important to consult your doctor who will determine the right dosage for you. Ensure to inform your doctor about any pre-existing conditions or ongoing medications. If you notice any side effects, notify your doctor immediately. For optimal results, continue taking the medicine for the duration prescribed by your doctor.

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Zonisep 25 Capsule is used for the following:

Managing partial seizures: This is when uncontrolled electrical disturbances occur in one area of your brain.
Adjunctive therapy in adults with epilepsy: Here, Zonisep 25 Capsule is used along with other medications to manage epilepsy.

Directions for Use of Zonisep 25 Capsule 10

Follow these instructions while taking Zonisep 25 Capsule:

Swallow the capsule whole with a glass of water.
Do not crush or chew the capsule.
If you miss a dose, take it as soon as you remember. However, if it's close to your next dose, skip the missed one.

Zonisep 25 Capsule is taken orally.

Taking Zonisep 25 Capsule may cause the following common side effects:

Drowsiness
Dizziness
Loss of appetite and weight loss
Nausea and diarrhoea
Confusion
Irritability
Depression
Headache
Double vision
Rash and itching

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Zonisep 25 Capsule. However, if you experience any serious side effects or worsening of any of the symptoms, please consult your doctor. Here are some general guidelines for managing common side effects:

Drowsiness and Dizziness: Consider taking this medicine at night to avoid these effects during the day.
Nausea and Diarrhoea: Try taking Zonisep 25 Capsule with food or milk to lessen these effects.

Zonisep 25 Capsule contains zonisamide (25 mg), which works on your body in several ways:

Blocking Voltage-Sensitive Sodium Channels: Zonisamide stabilises neuronal membranes and inhibits the spread of seizure discharges by blocking these channels.
Reducing Calcium Ion Flow: By reducing the flow of calcium ions into neurons, zonisamide helps control the release of neurotransmitters and neuronal excitability.
Enhancing GABA Activity: The medicine enhances the activity of GABA, a neurotransmitter that inhibits brain activity, thus helping manage seizures.
Weak Inhibition of Carbonic Anhydrase: Zonisamide inhibits carbonic anhydrase; however, this action is thought to contribute minimally to its antiseizure properties.

Pregnancy

Zonisep 25 Capsule should only be taken during pregnancy if the potential benefits outweigh the risks, as it may harm the unborn baby. Make sure to consult your doctor before starting this medicine.

Breastfeeding

Breastfeeding while taking this medication is not recommended. If you are breastfeeding, it's important to consult your doctor to understand the potential risks and benefits.

Alcohol

Avoid drinking alcohol while taking Zonisep 25 Capsule as it can increase the risk of side effects like drowsiness and dizziness.

Liver

Caution is advised while taking Zonisep 25 Capsule in case of liver impairment. If you have liver problems, discuss them with your doctor before starting this medicine. This medicine may affect liver function.

Kidney

If you have a history of kidney problems, caution is advised before using Zonisep 25 Capsule. It is a good idea to consult your doctor before taking this medicine.

Using Machines & Driving

Zonisep 25 Capsule may cause drowsiness and dizziness, so avoid driving or operating machinery until you know how the medication affects you.

Allergy

Zonisep 25 Capsule should not be used if you are allergic to zonisamide, sulfonamides, or any of the inactive ingredients.

Children

Zonisep 25 Capsule is not recommended for children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Zonisep 25 Capsule under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70.

Drug-Drug Interactions

Zonisep 25 Capsule interacts with the following medicines:

Antiepileptic medicines: Medicines like carbamazepine, phenytoin, and valproate may interact with Zonisep 25 Capsule, potentially altering the effectiveness and increasing the risk of side effects.
Oral contraceptives: Zonisep 25 Capsule may reduce the effectiveness of oral contraceptives.
Carbonic anhydrase inhibitors: Medicines such as acetazolamide and topiramate can interact with Zonisep 25 Capsule, potentially leading to adverse effects.
CYP3A4 inducers and inhibitors: Medicines like rifampin, ketoconazole, and erythromycin can affect how Zonisep 25 Capsule works in your body.

Drug-Food Interactions

Drug-Disease Interactions

Zonisep 25 Capsule interacts with the following diseases:

Liver disease: Patients with liver disease should use Zonisep 25 Capsule cautiously, as dose adjustments may be necessary.
Kidney disease: Those suffering from kidney disorders should also take care as this medication could affect kidney function.

Daily Dose

Your daily dose of Zonisep 25 Capsule is determined by your doctor, based on your individual requirements. The dosage can vary due to factors such as your response to the medicine and the severity of your condition. Always follow the dosage instructions given by your doctor.

Over Dose

If you accidentally take more than the prescribed dose, you may experience increased side effects such as dizziness, fatigue, and confusion. If these symptoms persist or worsen, inform your doctor.

Missed Dose

When you miss a dose of Zonisep 25 Capsule, take it as soon as you remember. However, if it's nearly time for your next dose, leave out the missed one and continue with your normal schedule. Do not increase your dosage without consulting with your doctor.

Store Zonisep 25 Capsule in a cool and dry place where the temperature is below 30°C.
Keep it protected from light and moisture.
Ensure it's out of the reach of children.
Always use this medicine before the expiry date mentioned on the packaging.

Stay well-hydrated: This can help reduce the risk of kidney stones, a possible side effect of Zonisep 25 Capsule.
Maintain a balanced diet: Since loss of appetite and weight loss are common side effects, it's important to ensure you're eating nutritiously to maintain your health while on this medication.

Fact Box

Drug Category	Antiepileptic
Therapeutic Category	Antiseizure
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Partial seizures, Epilepsy

What is the main use of Zonisep 25 Capsule?

Zonisep 25 Capsule is primarily used to manage partial seizures, which are sudden electrochemical disturbances in a part of the brain.

How does Zonisep 25 Capsule work?

Zonisep 25 Capsule works on certain channels and chemical substances in your brain which together help stabilise the nerve activity and prevent seizure discharges in the brain.

Can I take this medicine with food?

You can take this medicine with or without food. Consult your doctor for appropriate advice.

What should I do if I miss a dose?

If you miss a dose, take it as soon as you remember. However, if it's close to your next dose time; then skip the missed dose and continue with your next dose.

Can I stop taking Zonisep 25 Capsule when I feel better?

No, you shouldn't stop taking this medicine without consulting your doctor, even if you're feeling better.

Is it safe to drive after taking this medicine?

No, as this medicine may cause drowsiness and dizziness; thus hampering your ability to drive.

Can I take this medicine during pregnancy?

Consult your doctor before using this medication while pregnant. It is usually advised to use it if the potential benefits outweigh the risks.

Last Updated On 23 Dec. 2024 | 10:53AM (IST)

Certified Content

Written by

Dr Nikita Lobo

Medical Editor & Reviewer | 8 years

BDS, MDS

Reviewed by

Dr. Saniya K Mulla

Medical Writer & Reviewer | 6 years

MBBS

Check out Editorial Policy

Manufacturer details

SUN HOUSE CTS No. 201, 201, Western Express Hwy, Ram Nagar, Goregaon, Mumbai, Maharashtra 400063

Country of origin: INDIA

References

DailyMed. (n.d.). Zonisamide - Zonisamide capsule. https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=ab0631ca-5339-4570-bc27-f1dd92de1d6f. Accessed 1 April 2024.
U.S. Food & Drug Administration. (2016). Zonisamide. https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/020789s034lbl.pdf. Accessed 1 April 2024.
Kadian, R., & Kumar, A. (2022). Zonisamide. PubMed; StatPearls Publishing. https://www.ncbi.nlm.nih.gov/books/NBK507903/
Zonisamide: MedlinePlus Drug Information. (n.d.). Medlineplus.gov. https://medlineplus.gov/druginfo/meds/a603008.html

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We, at Truemeds make a diligent attempt to deliver accurate, expert- drafted and thoroughly reviewed medicine related information to our consumers. However, it should, by no means, be considered a substitute for prescription from a certified doctor or a trustworthy doctor-patient relationship. In fact we detest any form of self medication without expert advice. The sole purpose of the information on our portal is to educate our consumers, which helps improve the communication between a doctor and a patient. The information by no means is complete in its entirety and should not be used to diagnose or treat any medical condition. No amount of information can replace the experience and expertise of a doctor, therefore his/her advice always holds priority and should be followed appropriately.

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