Scabies

Scabies is a highly contagious skin condition that affects millions of people globally. Caused by the microscopic mite Sarcoptes scabiei, variety Hominis, scabies can lead to severe itching and a distinctive rash on the skin. The condition is transmitted through close skin-to-skin contact with an infected individual or by sharing infested personal items such as clothing, towels, or bedding. Despite being associated with poor hygiene, scabies can affect anyone, irrespective of age, socioeconomic status, or personal cleanliness. In this article, we will explore the various aspects of scabies, including its causes, symptoms, types, and treatment options, to help you better understand and manage this common skin infestation.

What is Scabies?

Scabies is a skin infestation caused by the tiny mite Sarcoptes scabiei. These mites burrow into the upper layer of the skin, where they live and lay eggs, leading to intense itching and a pimple-like rash. The rash typically appears in skin folds and other warm areas of the body, such as between the fingers, on the wrists, elbows, knees, armpits, waist, buttocks, and shoulder blades. In infants and young children, the rash may also develop on the head, face, neck, palms, and soles of the feet.

While scabies is generally recognised by its characteristic itching and rash, there are three main types of scabies, each with its own specific features:

• Typical scabies: This is the most common form of scabies, causing an itchy rash on the hands, wrists, and other common spots on the body. The rash usually consists of small, red, itchy bumps and thin, irregular burrow tracks.

• Nodular scabies: In this type, the infestation leads to the development of itchy, raised bumps or nodules, particularly around the genitals, armpits, or groin. These nodules are considered a hypersensitivity reaction to the presence of the female mite.

• Norwegian scabies (crusted scabies): This is a more severe and highly contagious form of scabies that usually affects individuals with weakened immune systems. It is characterised by thick, crusted skin lesions that contain thousands of mites and eggs. Unlike typical scabies, the rash associated with crusted scabies may not cause itching.

1. Common symptoms

• Intense itching: The most common symptom of scabies is intense itching, especially at night. This is caused by the body's allergic reaction to the Sarcoptes scabiei mite, its eggs, and faeces.

• Rash: Scabies often present with a pimple-like itchy rash. The rash commonly appears between fingers, in skin folds of the wrist, elbow, knee, or armpit, and on the penis, nipples, waist, buttocks, and shoulder blades.

• Burrows: Tiny raised, crooked lines on the skin surface are a characteristic sign of scabies. These are actually the burrows of the scabies mites.

• Specific areas affected: Scabies rash and symptoms commonly affect the wrists, elbows, armpits, nipples, penis, waist, buttocks, and the area between fingers.

2. Symptoms in infants and children

• Widespread rash: In infants and small children with scabies, the rash can be more widespread, covering most of the body, including palms, soles, and scalp.

• Irritability: Babies with scabies are often irritable and may have difficulty eating or sleeping owing to the discomfort caused by the infestation.

3. Severe forms

• Crusted (Norwegian) scabies: A more severe and highly contagious form of scabies, crusted or Norwegian scabies is characterised by thick skin crusts containing thousands of mites and eggs. This form is often seen in people with weakened immune systems.

1. Primary Cause

• Sarcoptes scabiei mites: Scabies is primarily caused by an infestation of tiny, eight-legged mites called Sarcoptes scabiei. These mites burrow into the top layer of human skin to live and feed, causing the characteristic symptoms of scabies.

2. Transmission

• Direct skin-to-skin contact: The most common method of transmission for scabies is direct skin-to-skin contact, including sexual contact.

• Infested furniture, clothes, and bedding: Though less common, scabies mites can also be spread through contact with infested items like furniture, clothes, and bedding.

1. Demographic and environmental factors

• Close living conditions: Scabies outbreaks are common in institutional settings such as hospitals, boarding schools, long-term care facilities, and refugee or internally displaced person camps due to overcrowding and increased skin-to-skin contact.

• Age: Scabies can affect people of all ages, but it is most common in children and the elderly. Young children are at higher risk due to their close contact with others in daycare or school settings. The elderly are more susceptible due to weakened immune systems and the likelihood of living in long-term care facilities.

• Compromised immune system: Individuals with weakened immune systems, such as those with HIV/AIDS, cancer, or organ transplant recipients, are at higher risk for contracting scabies and developing crusted scabies.

2. Behavioral Factors

• Skin-to-skin contact: Direct skin contact with an infected person, especially if they have an itchy rash, significantly increases the risk of transmission. This includes sexual contact, holding hands, or sharing a bed.

• Sharing personal items: Scabies mites can survive for a short period on clothing, bedding, or towels. Sharing these items with an infested person increases the risk of contracting scabies.

Scabies can lead to several complications if left untreated or improperly managed:

• Secondary bacterial infections: Scabies can pave the way for secondary bacterial infections, particularly with Streptococcus pyogenes and Staphylococcus aureus. These infections can manifest as impetigo, cellulitis, and in severe cases, pyelonephritis, abscesses, pyogenic pneumonia, sepsis, and even death.

• Persistent itching and insomnia: Even after successful treatment, patients may experience persistent itching for 2-4 weeks due to the immune system's reaction to dead mites and their products. This can lead to sleeplessness and may require additional treatments like antihistamines or topical steroids.

• Community outbreaks: Untreated or improperly treated scabies can spread rapidly within communities, especially in closed environments such as residential aged care facilities and schools, leading to outbreaks.

• Postscabietic reactions: Patients may experience reactions like Id reactions (auto-eczematisation) and epidermal changes due to topical treatments, which can prolong the recovery period.

1. Hygiene and cleanliness

• Regular handwashing: Frequent handwashing with soap and warm water, especially after direct contact with an infected person or their belongings, can help prevent the spread of scabies mites.

• Avoiding shared items: Do not share clothing, bedding, or towels with someone who has scabies. If you suspect contamination, wash these items in hot water and dry them on high heat to kill the mites.

• Cleaning the environment: Vacuum carpets, upholstered furniture, and car seats to remove any fallen mites. Consider using a steam cleaner for added effectiveness.

2. Early diagnosis and treatment

• Seek medical attention: If you suspect that you or a family member has scabies, consult a doctor for proper diagnosis and treatment. Early intervention can prevent the spread of the infestation.

• Treat all close contacts: When one person in a household is diagnosed with scabies, all household members and close contacts should be treated simultaneously, even if they do not have symptoms. This helps prevent re-infestation.

3. Awareness and education

• Know the signs and symptoms: Educate yourself and others about the signs and symptoms of scabies, such as intense itching (especially at night), a pimple-like rash, and threadlike burrows in the skin.

• Spread awareness: If you or someone in your family has scabies, inform close contacts, such as friends, classmates, or colleagues, so they can watch for symptoms and seek treatment if necessary.

1. Clinical diagnosis

• Visual inspection: In many cases, a doctor can diagnose scabies based on the appearance of the rash and the presence of burrows. They will visually inspect the skin, looking for characteristic signs of scabies infestation.

• Symptom review: The doctor will also ask about symptoms such as intense itching (especially at night), the location of the rash, and any potential exposure to scabies.

2. Microscopic examination

• Skin scraping: To confirm the diagnosis, the doctor may take a skin scraping from an affected area, such as a burrow. This sample is then examined under a microscope to look for mites, their eggs, or fecal matter.

• Ink test: In some cases, the doctor may apply ink to the affected area and then wipe it off. If burrows are present, the ink will seep into them, making them more visible.

3. Differential diagnosis

• Rule Out Other Conditions: Scabies symptoms can be similar to other skin conditions, such as eczema, psoriasis, or contact dermatitis. The doctor will consider these possibilities and may perform additional tests to rule them out.

4. Challenges in diagnosis

• Atypical presentations: In some cases, especially in infants, the elderly, or those with weakened immune systems, scabies may present atypically, making diagnosis more challenging.

• Delayed symptoms: It can take up to 6 weeks for symptoms to appear after initial infestation, which may delay diagnosis and treatment.

1. Medications

Scabies can be effectively managed and treated using several medication options, all of which require a prescription:

• Topical permethrin 5% cream: This is the first-line treatment for scabies and is approved for use in people aged 2 months and older. It is applied to the entire body from the neck down and left on for 8-14 hours before being washed off. Multiple applications may be necessary to eliminate all mites.

• Oral ivermectin: Although not approved for scabies, ivermectin is often prescribed, especially for cases of crusted scabies or in individuals with compromised immune systems. It is not recommended for pregnant women or children weighing less than 15 kg.

• Other topical treatments: These include crotamiton lotion 10%, sulfur ointment 5-10%, malathion lotion 0.5%, and spinosad topical suspension 0.9%. Each has its own specific application instructions and limitations.

2. Special Considerations

• Crusted scabies: This severe form of scabies requires intense treatment with both topical and oral medications. Ivermectin is often used in combination with topical permethrin, and multiple doses may be necessary.

• Children and infants: For young children and infants, only specific scabicides recommended by their paediatrician should be used. Sulfur ointment is safe for infants under 2 months old.

After treatment, itching can persist for several weeks due to a hypersensitivity reaction to the mites and their faeces. Additional treatments may be necessary if symptoms persist or new burrows or rashes appear.

Living with scabies requires a combination of good hygiene practices, treatment compliance, and symptom management:

• Hygiene and isolation: To prevent the spread of scabies, wash all bedding, towels, and clothes in hot water (at least 60°C) and dry them on a hot setting. Seal items that cannot be washed in a bag for 8 days or expose them to sunlight. Patients should avoid close contact with others for at least 24 hours after the first treatment.

• Treatment compliance: Treat all household contacts and recent sexual partners simultaneously to prevent reinfestation. Scabies treatment typically involves applying a scabicide cream or taking oral medication, with a repeat application usually required. Adherence to the treatment regimen is critical to avoid treatment failure.

• Managing symptoms: Intense itching can be managed with oral sedative antihistamines to improve sleep quality. However, be aware that these antihistamines can cause drowsiness and should be used with caution.

By following these guidelines, individuals with scabies can effectively manage the condition and prevent its transmission to others.

There are certain situations when it is important to seek medical attention:

• Severe or persistent symptoms: If you experience severe itching, extensive rash, or symptoms that do not improve after self-treatment, consult your doctor for further evaluation and treatment.

• High-risk individuals: If you are immunocompromised, pregnant, elderly, or have a chronic skin condition, seek medical advice before starting any scabies treatment.

• Recurrent infections: If you experience repeated scabies infections despite proper treatment, consult your doctor to rule out other underlying health issues or to identify potential sources of reinfestation.

• Concerns about treatment: If you have any concerns or questions about the appropriate use of scabies medications or experience adverse reactions to treatment, contact your doctor for guidance.

Remember, prompt medical attention can help prevent complications and ensure effective management of scabies.

• Scabies is a contagious skin condition caused by the Sarcoptes scabiei mite, which burrows into the skin and lays eggs, causing an intensely itchy rash.

• Scabies is transmitted through close skin-to-skin contact or, less commonly, through sharing contaminated bedding or clothing.

• Symptoms of scabies include intense itching (especially at night), a pimple-like rash, and burrow tracks on the skin. Commonly affected areas include the wrists, elbows, armpits, webbing between fingers, nipples, waist, buttocks, and genital area.

• Diagnosis is typically based on the appearance of the rash and the presence of burrows. In some cases, skin scraping may be examined under a microscope to confirm the presence of mites or eggs.

• Treatment usually involves applying a scabicide cream or lotion (such as permethrin or benzyl benzoate) to the entire body from the neck down and leaving it on for the recommended time. Oral medications like ivermectin may be prescribed in some cases.

• To prevent reinfestation, it is essential to treat all close contacts simultaneously, wash bedding and clothing in hot water, and practice good hygiene.