Adapalene + Clindamycin

Dosage Forms Available

• This combination is applied topically (gel and cream).

Age and Dose Restrictions

• This combination can be used in adults and children above 12 years of age.

Contraindications

• It is contraindicated in patients with a history of hypersensitivity to adapalene or clindamycin or other lincomycin preparations.

Medications to Avoid with This Drug

• Avoid taking neuromuscular blocking agents and applying topical antibiotics containing erythromycin. These medications may alter the safety and effectiveness of Adapalene + Clindamycin.

Overdose and Missed Dose

• Apply this combination on the affected area as your doctor prescribes. Follow their prescribed dosage and do not exceed it without consulting them.
• You may apply the missed dose of this combination as soon as you remember and continue with your regular dosing schedule.

Management of Side Effects

• The side effects of this combination are temporary and resolve on discontinuation. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.

Use In Driving And Operating Machinery

• It is unlikely to impair the mental alertness or coordination required while driving.

Use in Pregnancy and Lactation

• Caution is advised in pregnancy and breastfeeding.

Caution in Other Conditions

• Caution is advised in patients with sensitive skin, allergic contact dermatitis, and a history of ulcerative or antibiotic-associated colitis.

Special Dietary & Lifestyle Recommendation

• Do not apply this combination directly to the nipple and areola to avoid getting it into your baby’s mouth.
• Apply a broad-spectrum sunscreen before sun exposure, as topical clindamycin may increase sensitivity to sunlight. This precaution helps prevent sunburn and minimises the risk of hyperpigmentation.
• Use non-comedogenic moisturisers to keep the skin hydrated and protected.
• Avoid excessive touching, picking, or squeezing of acne lesions, leading to further inflammation and potential scarring.
• Avoid harsh scrubbing or over-washing, which can irritate the skin and worsen acne.
• Do not apply it to open wounds, cuts, or damaged skin, as it may cause irritation or blood absorption of its ingredients.