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Azelastine + Fluticasone Propionate

Uses of Azelastine + Fluticasone Propionate

  • The primary use of Azelastine + Fluticasone Propionate is to manage symptoms of seasonal and perennial (year-round) allergic rhinitis in adults and children aged 6 years and above. It belongs to the class of antihistamine and corticosteroid medications.

  • In addition, it can also provide relief from itchy, watery eyes caused by allergies.

Side effects of Azelastine + Fluticasone Propionate

  • Bitter taste in the mouth

  • Headache

  • Nasal discomfort or burning sensation

  • Nosebleeds

  • Nausea

How Azelastine + Fluticasone Propionate works

  • Azelastine + Fluticasone Propionate is a combined antihistamine and corticosteroid nasal spray.

  • Azelastine, the antihistamine component, works mainly by blocking histamine receptors. Histamine is a substance released in the body during an allergic reaction and it causes symptoms like sneezing, itching, and runny nose. By blocking its receptors, Azelastine helps prevent these symptoms.

  • Fluticasone Propionate, on the other hand, is a synthetic corticosteroid. It works by reducing the inflammation in your nasal passages. As inflammation is a key factor in many allergic reactions, this reduction can help ease symptoms such as swelling and mucus production.

  • Together, these two components of Azelastine + Fluticasone Propionate work to provide fast and long-lasting relief from bothersome nasal allergy symptoms.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Azelastine + Fluticasone Propionate is available for use via the nasal route as a nasal spray.

Age and Dose Restrictions

  • This medicine is meant for use in adults and children aged 6 years and older.

Contraindications

  • Azelastine + Fluticasone Propionate is contraindicated in individuals with known allergies to any of its ingredients.

  • It should not be used by those with untreated fungal, bacterial, or tuberculosis infections of the respiratory tract.

Other Medications to Avoid

  • This combination may interact with cimetidine, ketoconazole and other azole antifungals (like fluconazole, itraconazole), potent CYP3A4 inhibitors (such as indinavir, ritonavir).

Overdose and Missed Dose

  • Overdose with Azelastine + Fluticasone Propionate nasal spray may result in symptoms like nasal irritation and headache. Supportive care is usually sufficient in managing these symptoms.

  • If you miss a dose of Azelastine + Fluticasone Propionate, administer it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for the missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • If experiencing a bitter taste after administration, rinsing the mouth with water may help.

  • Staying hydrated can help manage headache symptoms.

Use in Driving and Operating Machinery

  • Azelastine + Fluticasone Propionate may cause drowsiness. You should avoid driving or operating heavy machinery if you feel sleepy after using this nasal spray.

Use in Pregnancy and Lactation

  • The safety of using Azelastine + Fluticasone Propionate during pregnancy or while breastfeeding has not been established. It is important to consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Patients who have recently had nasal surgery or removed nasal polyps should use Azelastine + Fluticasone Propionate with caution. Consultation with a doctor is advised before using this medication under these conditions.

Special Dietary and Lifestyle Recommendations

  • For individuals using Azelastine + Fluticasone Propionate to manage allergic rhinitis, avoiding known allergens can help reduce the frequency and severity of symptoms.

  • Maintaining a dust-free environment at home and at work can also help minimize allergic reactions.

  • Consider using a dehumidifier in damp areas to prevent the growth of moulds that might aggravate nasal allergies.

  • Regular washing of bed linens in hot water can help eliminate dust mites.

  • For outdoor allergens like pollen, staying indoors on high pollen days and keeping windows closed can reduce exposure.

Frequently asked questions

Yes, Azelastine + Fluticasone Propionate is partly a steroid. Fluticasone Propionate is a steroid, while Azelastine is an antihistamine.

Yes, one of the side effects of Azelastine + Fluticasone Propionate can be sleepiness.

There are no known effects of Azelastine + Fluticasone Propionate on fertility. However, it is always advisable to consult your doctor if you have any concerns.

No specific diet restrictions are mentioned for Azelastine + Fluticasone Propionate. However, maintaining a healthy diet is always beneficial.

Yes, it is generally safe to use Azelastine + Fluticasone Propionate daily as prescribed by your doctor. However, children's growth should be monitored with prolonged use.

Some people may experience symptom relief within 30 minutes of administering the first dose of Azelastine + Fluticasone Propionate. However, it may take several days of regular use to achieve the full effect.

Azelastine + Fluticasone Propionate can be taken at any time of the day that works best for you, typically once or twice a day as prescribed by your doctor. It does not need to be taken with meals.

Terms & Conditions


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