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Benzoyl Peroxide

Uses of Benzoyl Peroxide

  • The primary use of Benzoyl Peroxide is in managing mild to moderate acne vulgaris (chronic skin condition that occurs when hair follicles become clogged with oil and dead skin cells). It belongs to the group of topical acne medications.

  • Besides treating acne, Benzoyl Peroxide is also used off-label for managing other skin conditions like rosacea (long-term, non-contagious skin condition that causes redness), folliculitis (skin condition that causes inflammation and infection of one or more hair follicles), and seborrheic dermatitis (chronic skin condition that causes flaky, oily, and itchy or inflamed patches of skin).

Side effects of Benzoyl Peroxide

  • Local skin reactions like erythema (abnormal redness of the skin), dryness, peeling

  • Burning or stinging sensation

  • Allergic contact dermatitis in rare cases

  • Temporary skin bleaching or discolouration of hair/fabrics

How Benzoyl Peroxide works

  • Benzoyl Peroxide is an antibacterial and anti-inflammatory agent.

  • It works by releasing free-radical oxygen that oxidises bacterial proteins in Propionibacterium acnes (the primary bacteria causing acne). This reduces the amount of P. acnes in sebaceous follicles, reducing bacterial activity. It also loosens the connections between the skin's outermost cells, promoting exfoliation. This aids in unclogging blocked pores and prevents the formation of comedones or blackheads and whiteheads. Lastly, it also has an anti-inflammatory effect. By reducing P. acnes, it decreases the production of inflammatory substances that cause redness and swelling in acne lesions. In this way, this medicine manages acne effectively.

Certified content

Written By

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Dr Nikita LoboMedical Editor & Reviewer| 7 years

BDS, MDS

Reviewed By

Dr. Osama Ahmed
Dr. Osama AhmedDental/Medical Writer, Editor, Reviewer| 2 years

Bachelor of Dental Surgery

Expert Advice

Dosage Forms Available

  • Benzoyl Peroxide is available in various topical formulations, including creams, gels, lotions, pads, soaps, liquids, and foams.

Age and Dose Restrictions

  • Benzoyl Peroxide is generally safe for use by adults and teenagers suffering from acne vulgaris (chronic skin condition). For children, it is always advisable to consult a doctor before use.

Contraindications

  • This medicine is contraindicated in individuals who have a known hypersensitivity to Benzoyl Peroxide or any other ingredients in its formulation. It should not be used on broken skin or open wounds, or if you have lung or breathing disease (asthma).

Other Medications to Avoid

  • Benzoyl Peroxide can interact with other potentially irritating agents (e.g., harsh cleansers, alcohol-based preparations, astringents, spices, lime) and topical acne medications (e.g., adapalene, isotretinoin).

Overdose and Missed Dose

  • Overdose of Benzoyl Peroxide may result in excessive dryness or peeling of the skin. If you suspect an overdose, stop the medication and consult your doctor immediately.

  • If you forget to apply this medicine at the scheduled time, apply it as soon as you remember. However, if it is close to the time for your next application, skip the missed dose and continue with your regular schedule.

Management of Side Effects

  • Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Applying a moisturizer can help manage skin dryness.

  • Reducing application frequency may alleviate skin irritation and burning sensation.

Use in Driving and Operating Machinery

  • As a topical medication, Benzoyl Peroxide does not affect your ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • The safety of Benzoyl Peroxide during pregnancy and breastfeeding has not been fully established. Consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Benzoyl Peroxide should be used with caution on sensitive areas such as the neck, underarms etc., to avoid skin irritation. Patients with sunburn should avoid applying this medicine as it may exacerbate the irritation. It should not be used alongside products containing sulfur, resorcinol, or salicylic acid due to the risk of temporary dark spots.

Special Dietary and Lifestyle Recommendations

  • Maintain a regular facial cleansing routine to keep your skin clean and free from excess oil and dirt.

  • Avoid touching your face with dirty hands to prevent the spread of bacteria that can exacerbate acne.

  • Avoid using harsh scrubs or exfoliants on acne-prone skin, as they can worsen inflammation.

Frequently asked questions

No, Benzoyl Peroxide is not an antibiotic. It is a type of organic peroxide compound with antibacterial, keratolytic, and comedolytic properties that helps manage acne.

While primarily indicated for treating acne, Benzoyl Peroxide is sometimes used off-label to manage other skin conditions such as rosacea, folliculitis, and seborrheic dermatitis.

Yes, it is recommended to use sunscreen after applying Benzoyl Peroxide because prolonged sun exposure can cause skin irritation when using this medication.

Benzoyl Peroxide works by reducing the bacteria causing acne and helping to unclog pores. It does not have any known effects on hormones.

During the initial weeks of use, Benzoyl Peroxide may cause skin purging where pimples and blackheads (small bumps due to clogged hair follicles) come to the surface. This is a normal and temporary phase and does not mean your acne is getting worse.

You may notice some improvement in 1-2 weeks of consistent use, with maximum benefit found in 4-8 weeks.

Benzoyl Peroxide can be applied daily if prescribed by a doctor, but it is prudent to start with a lower strength and gradually increase if needed, particularly if skin irritation occurs.

Terms & Conditions


Benzoyl Peroxide in other salts

Available medicines for BENZOYL PEROXIDE
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Clinfresh Soap 75gm
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Benzac Ac 5% Gel 30gm
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Perobar 2.5% Soap 75gm
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