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Betamethasone

TOPICAL STEROID

Uses of Betamethasone

  • Betamethasone is a corticosteroid used as an immunosuppressive and anti-inflammatory agent in a variety of conditions like skin diseases such as dermatitis, psoriasis, etc
  • It can be used in the treatment of several autoimmune disorders rheumatoid arthritis ,systemic lupus erythematosus, Crohn’s disease.
  • It is also used in various allergic conditions such as asthma and in some forms of leukaemia.
  • It is also indicated for use in pregnant women who are at risk of preterm delivery to aid foetal lung maturation.

Side effects of Betamethasone

  • Itching, redness, and burning at the site of the application
  • Muscle weakness
  • Increased risk of infections or flaring up of existing infections
  • Prolonged use can potentially cause Adrenal insufficiency and Psychiatric symptoms.

How Betamethasone works

  • Betamethasone is a corticosteroid (glucocorticoid)
  • It is a glucocorticoid receptor agonist that controls the rate of protein synthesis by which it inhibits the formation and migration of pro-inflammatory molecules and promotes anti-inflammatory activity, thereby leading to reduced inflammation.

Certified content

Written By

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Amit SharmaClinical Health & Medical Writer| 3 Years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 12 Years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Betamethasone is available for use via oral (tablet, capsule), parenteral (i/v, i/m), and topical (cream, lotion, gel) routes.

Age And Dose Restrictions

  • It can be used in both adults and children with appropriate dose calculation.

Contraindications 

  • It is contraindicated in patients allergic to betamethasone.

Medications To Avoid With This Drug

  • It is advisable to inform your doctor regarding all the medications that you are taking so that he/she can decide regarding the use of Betamethasone or its dose adjustment if needed.

Overdose And Missed Dose

  • If a dose is missed, it should be taken if there is a time gap from the subsequent dose. If not, then a routine dosing regimen should be followed.
  • Chronic high doses of betamethasone can cause cataracts, glaucoma, hypertension, water retention, hyperlipidemia, mood changes etc. It is important to inform your doctor regarding these effects who will taper the dose of betamethasone and initiate a symptomatic treatment. 

Use In Driving And Operating Machinery

  • It is unlikely to impair the mental alertness or coordination required while driving.

Use In Pregnancy And Lactation

  • Betamethasone use during pregnancy and lactation is permissible but requires caution.

Caution In Other Conditions

  • Caution is advised for use of Betamethasone in patients with kidney or liver disease.

Special Dietary And Lifestyle Recommendation

  • Alcohol consumption should be avoided when using betamethasone.
  • Betamethasone should not be stopped abruptly. Its dose is gradually tapered before stopping it. 
  • Patients who are on a longer duration of treatment with betamethasone should have restrictions on sodium and potassium intake. Also, patients suffering from cholesterol problems need to monitor their lipid levels closely. 

Frequently asked questions

Yes. However, take the advice of a doctor before using betamethasone in pregnancy.

Topical betamethasone takes 3 to 4 days to show their action.

Yes. However, take the advice of a doctor before using betamethasone while breastfeeding.

The precautions and warnings to be followed while taking betamethasone are; Do not use Betamethasone if you are allergic to it, Be careful when applying it around the eyes, and rinse your eyes with water if it accidentally enters your eyes, Be cautious about the use of betamethasone in children as their skin is softer and may need dose adjustment.

No. Betamethasone should not be stopped before completion of the prescribed duration as it can precipitate withdrawal symptoms.

Terms & Conditions


Betamethasone in other salts

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