Bisacodyl
Uses of Bisacodyl
- Bisacodyl is used on a short-term basis to treat occasional constipation and to empty the bowels before surgery and certain medical procedures, such as colonoscopy. It belongs to the class of medications known as stimulant laxatives.
- Additionally, Bisacodyl is effective in managing neurogenic bowel dysfunction in patients with spinal cord injuries.
Side effects of Bisacodyl
Abdominal cramps or pain
Nausea and vomiting
Diarrhoea
Dizziness or faintness
Anorectal irritation or burning (with suppositories/enemas)
How Bisacodyl works
Bisacodyl is used to treat constipation or to empty the bowels before surgical procedures.
Bisacodyl belongs to a class of medicines known as stimulant laxatives.
It works inside the large intestine. Here, it gets changed into its active form, bis-(p-hydroxyphenyl)-pyridyl-2-methane (BHPM), by the bacteria naturally found there. BHPM alters the transport of electrolytes, importantly sodium and potassium, leading to the accumulation of fluid in the colon. This helps to soften the stool. In addition, it stimulates the muscles of the colon causing contractions, known as peristalsis, through the release of certain chemicals including prostaglandin E2. It also acts on the nerve endings in the intestine, which further aids in promoting peristalsis.
Certified content
Written By
Doctor of Medicine
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Bisacodyl can be taken orally (enteric-coated tablets). It is also available as rectal suppositories and enemas for rectal administration.
Age and Dose Restrictions
This medicine is meant for adults and children above 6 years of age.
Contraindications
Bisacodyl is contraindicated in patients with known hypersensitivity to it or any of the inactive ingredients. Patients with intestinal obstruction, severe dehydration, acute surgical abdominal conditions, toxic megacolon and undiagnosed rectal bleeding are advised not to take this medicine.
Other Medications to Avoid
This medication may interact with diuretics (such as furosemide, and hydrochlorothiazide), antacids (such as aluminium hydroxide, and magnesium hydroxide), oral anticoagulants (like warfarin, and apixaban) and other laxatives (like senna, lactulose).
Overdose and Missed Dose
An overdose of Bisacodyl may cause severe vomiting, diarrhoea or abdominal pain. If you suspect an overdose, immediately inform your doctor and follow the advice accordingly.
If you forget to take this medicine, take it as soon as you remember. However, if it is close to the time for your next dose, skip the missed dose and continue your regular dosing schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve after discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
If you experience nausea, try taking this medicine with food.
Drink plenty of water to manage the side effects of thirst or dry mouth.
Use in Driving and Operating Machinery
Bisacodyl may cause dizziness or faintness in some individuals. If you feel dizzy or faint after taking this medicine, avoid driving or operating heavy machinery.
Use in Pregnancy and Lactation
Bisacodyl tablets are generally not recommended in pregnancy. This medicine should be used during pregnancy and breastfeeding only if clearly needed and recommended by your doctor.
Caution in Other Conditions
Patients with severe dehydration should exercise caution when taking Bisacodyl. Individuals with spinal cord injuries may need dose adjustments and should consult their doctor before starting this medicine.
Special Dietary and Lifestyle Recommendations
Increase dietary fibre intake by consuming whole grains, fruits and vegetables to ease constipation.
Staying hydrated by drinking enough fluids can help prevent constipation.
Regular physical activity can stimulate intestinal activity and help manage constipation.
Frequently asked questions
Is Bisacodyl a steroid?
No, Bisacodyl is not a steroid. It belongs to the class of medications known as stimulant laxatives.
Does Bisacodyl have any effect on sleep?
Bisacodyl is not directly associated with affecting sleep. However, it can cause abdominal cramps or discomfort that might disrupt sleep. If such a situation arises, please consult your doctor.
Will Bisacodyl affect fertility?
There are no known effects of Bisacodyl on fertility in humans.
How should I store Bisacodyl tablets?
Store Bisacodyl tablets at room temperature (15-30°C) in a tightly closed container, away from heat, light, and moisture. Keep out of reach of children and pets.
Is it safe to take Bisacodyl daily?
Long-term daily use of stimulant laxatives like Bisacodyl is not recommended, as this can lead to laxative dependence and electrolyte disturbances. It should be used for short-term relief from constipation or bowel preparation.
How much time does Bisacodyl take to work?
Oral Bisacodyl typically induces a bowel movement within 6-12 hours, while rectal forms (suppositories, enemas) work more quickly, usually within 1 hour.
What is the best time to take Bisacodyl?
Bisacodyl should be taken on an empty stomach for optimal efficacy. However, it would be best if you always took it as directed by your doctor.
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