The primary use of Calcitriol/ Cholecalciferol is to treat and prevent vitamin D deficiency-related conditions. It belongs to the class of Vitamin D analogues.
Secondary uses of Calcitriol/ Cholecalciferol include management of conditions such as rickets in children, osteomalacia in adults, secondary hyperparathyroidism in patients with chronic kidney disease, postmenopausal osteoporosis, and also as a supplement when vitamin D requirements are high such as in growing children and elderly individuals.
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Calcitriol/ Cholecalciferol is a form of vitamin D. It works by aiding the body in absorbing calcium and phosphate from the food consumed. This helps to maintain good bone health and also helps muscles work well. Additionally, it also assists in maintaining the balance of these substances in the body, which is essential for the normal functioning of nerves, muscles, and the immune system. By controlling the levels of calcium and phosphate in the body, it helps to manage conditions such as rickets in children, osteomalacia in adults and bone disorders caused due to parathyroid gland problems.
BDS, MDS
BMS, FMC, MD Resident
Calcitriol/ Cholecalciferol can be taken orally (capsule and solution) and intravenous (injection) routes.
Calcitriol/ Cholecalciferol is intended for use in adults and children above the age of one year.
Calcitriol/ Cholecalciferol is contraindicated in patients with known allergy to vitamin D or any of the inactive ingredients in the formulation. It is also contraindicated in patients with severe renal or liver disease, hypercalcaemia (high blood calcium levels), and malabsorption syndromes.
Calcitriol/ Cholecalciferol may interact with seizure medicine (e.g., phenobarbital, phenytoin), cardiac glycosides (e.g., digoxin, digitalis), magnesium-containing medications (e.g., magnesium oxide, citrate of magnesia), and steroid medicine (e.g., prednisone, dexamethasone).
An overdose of Calcitriol/ Cholecalciferol may lead to serious side effects such as nausea, vomiting, constipation, muscle weakness, mental/mood changes, and abnormal heart rhythm. If you suspect an overdose, seek medical attention immediately.
If you miss a dose of Calcitriol/ Cholecalciferol, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not take double doses to make up for a missed one.
Most side effects of Calcitriol/ Cholecalciferol are temporary and tend to resolve once the body adjusts to the medication. However, if you experience persistent or worsening side effects, consult your doctor.
To manage symptoms of nausea or constipation, taking the medication with a meal may help.
To manage symptoms of dry mouth, sipping water frequently or chewing sugar-free gum may help stimulate saliva production.
Calcitriol/ Cholecalciferol does not usually affect your ability to drive or operate machinery. However, if you experience dizziness or any other side effect that could affect your concentration or alertness, avoid driving or operating heavy machinery.
The use of Calcitriol/ Cholecalciferol during pregnancy or lactation should be done only under the guidance of a doctor, who will decide whether the potential benefits outweigh any potential risks to the foetus or nursing infant.
Patients with heart disease should exercise caution when taking Calcitriol/ Cholecalciferol due to potential risks.
Expose your bare skin to the sun for 5–30 minutes a day to produce vitamin D naturally. However, you should still wear sunscreen and protective clothing to avoid sun damage.
Eat foods that are fortified with vitamin D such as almond, soy, and oat milks.
Frequently asked questions
No, Calcitriol/ Cholecalciferol is not a steroid. It is a form of Vitamin D3 which is crucial for maintaining good bone health and other physiological functions.
There is no direct link between Calcitriol/ Cholecalciferol and sleep. If you experience any sleep disturbances consult your doctor immediately.
No, Calcitriol/ Cholecalciferol does not have a direct impact on fertility. However, it is always recommended to discuss any concerns with your doctor before starting a new medication.
The safety of daily use of Calcitriol/ Cholecalciferol depends on several factors including the individual's specific medical condition, overall health status, and the advised dosage by the doctor.
The onset of action and time to achieve therapeutic effects of Calcitriol/ Cholecalciferol may vary depending on the condition being treated. In general, improvement in bone mineralization and calcium metabolism can be seen within a few weeks to months of starting therapy.
Calcitriol/ Cholecalciferol is essentially a form of vitamin D. While low vitamin D levels have been linked with mood disorders like depression, taking supplements like Calcitriol/ Cholecalciferol can help manage these conditions.
No, there is no direct evidence showing that taking Calcitriol/ Cholecalciferol can cause weight gain. If you have concerns about your weight or diet, it is best to discuss them with your doctor.
Calcitriol/ Cholecalciferol in other salts
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