Carbamazepine
ANTIEPILEPTICUses of Carbamazepine
- Carbamazepine is an anti-epileptic medicine that is used either as monotherapy or in conjunction with other medications to manage specific seizure types in individuals with epilepsy.
- Additionally, it is prescribed for the treatment of trigeminal neuralgia, a condition characterised by facial nerve pain.
Side effects of Carbamazepine
- Dizziness
- Constipation
- Drowsiness
- Constipation
- Dry mouth
- Problems in walking and coordination
- Altered speech
- Abnormal thinking
How Carbamazepine works
- Carbamazepine is an anticonvulsant medication that exerts its effects by stabilising electrical activity in the brain and nerves.
- In epilepsy, it prevents the accumulation of electrical signals in nerve cells, subsequently reducing the release of the neurotransmitter glutamate associated with seizures.
- In treating nerve pain, it stabilises electric signals in the nerves, inhibiting the transmission of pain signals to the brain.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available
- Carbamazepine is available for use via the oral route (tablet, a chewable tablet, an extended-release (long-acting) tablet, an extended-release capsule, and as a suspension (liquid)).
Age and Dose Restrictions
- This medicine is meant for adults and children above 5 years of age.
Contraindications
- Carbamazepine is contraindicated in patients with known allergies to carbamazepine and who have a history of previous bone marrow depression.
Other Medications To Avoid With This Medicine
- It is advisable to avoid concurrent use of antipsychotics (aripiprazole, quetiapine), anxiolytics (alprazolam), antidepressants (amitriptyline, duloxetine, sertraline, fluoxetine), antibiotics (erythromycin), analgesics (codeine, oxycodone, acetaminophen, tramadol), anticonvulsants (gabapentin, lamotrigine, pregabalin, phenytoin, topiramate), thyroid hormones (levothyroxine), antipsychotic agents (lithium), sedatives (melatonin), anticoagulants (warfarin), antihistamines (diphenhydramine), and vitamins (cholecalciferol) alongside Carbamazepine. Prior consultation with your healthcare provider is essential before considering any prescription or over-the-counter medications.
Overdose and Missed Dose
- Overdose of this medicine may cause symptoms like unconsciousness, seizures, muscle twitching, abnormal movements, unsteadiness, drowsiness, irregular or slowed breathing, vision changes, and difficulty urinating. If you observe these symptoms, inform your doctor and follow the advice accordingly.
- If you forget to take this medicine, take it as soon as you remember. But avoid repeating the dose.
Use In Driving And Operating Machinery
- This medicine may affect your ability to drive or operate heavy machinery. Avoid driving if you feel dizzy after taking this medicine.
Use in Pregnancy and Lactation
- Carbamazepine is not recommended during pregnancy or breastfeeding.
Special Dietary & Lifestyle Recommendation
- Avoid alcohol when you are taking Carbamazepine.
- People dealing with epilepsy are advised to contemplate lifestyle adjustments, including dietary modifications such as adopting a ketogenic diet, which is low in carbohydrates and high in healthy fats, and maintaining a regular sleep pattern along with Carbamazepine.
- Avoid grapefruit juice when taking Carbamazepine, as it can affect the working of Carbamazepine.
Frequently asked questions
1. How much time does Carbamazepine take to work?
The onset of action of this medicine may require 1 to 2 weeks for full efficacy to be realised.
2. What warnings and precautions should I take while taking Carbamazepine?
Individuals with a known allergy to Carbamazepine or its components should refrain from its usage. Consumption of alcohol or grapefruit juice alongside this medication is contraindicated due to potential interactions that may heighten the risk of severe side effects, including muscle pain. Complete disclosure of medical history and ongoing medications warrants communication with your doctor.
3. Can I stop taking Carbamazepine if I feel healthy?
Do not stop taking this medicine without consulting your doctor, even if you feel healthy.
4. Is it safe for patients with kidney or liver issues?
Consult your doctor before taking this medicine if you have kidney or liver issues to ensure its safety and proper dosage.
5. Can I take Carbamazepine before or after surgery?
Continue using this medicine both pre and post-surgery. Note that this medicine may attenuate the efficacy of certain muscle relaxants, necessitating potential dosage adjustments. Inform your healthcare provider about your carbamazepine regimen in case of surgical procedures.
6. Will Carbamazepine affect contraception?
Yes, this medicne can affect contraception. Inform your doctor before using any contraceptives.
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