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Clindamycin

ANTIBIOTIC

Uses of Clindamycin

  • Clindamycin is in a class of medications called lincomycin antibiotics. Clindamycin is used to treat certain types of bacterial infections,  skin, including infections of the lungs, blood and internal organs.
  • Additionally, Clindamycin is utilised for severe infections like osteomyelitis, septicemia, and endocarditis when other antibiotics are ineffective

Side effects of Clindamycin

  • Stomach pain
  • Diarrhoea
  • Nausea
  • Metallic taste in the mouth
  • Thick and white vaginal discharge

How Clindamycin works

  • Clindamycin is an antibiotic that effectively combats bacterial infections by interfering with their protein synthesis.
  • Clindamycin targets bacterial ribosomes, which are the cellular structures responsible for protein production.
  • By binding to the ribosomes, it inhibits protein synthesis and prevents them from functioning correctly. 
  • As a result, without the ability to produce essential proteins, bacteria cannot grow and multiply

Certified content

Written By

docImg
Amit SharmaClinical Health & Medical Writer| 3 years

B. Pharm

Reviewed By

Amatul Ameen
Amatul Ameen Clinical Health & Medical Writer| 13 years

B. Pharm, MSc.

Expert Advice

Dosage Forms Available

  • Clindamycin is available via the oral route (capsule, solution), intramuscular (injection) and intravenous administration (infusion) and topical administration ( foam, gel and lotion).

Age And Dose Restrictions

  • It can be used for adults and children with appropriate dose adjustments.

Contraindications 

  • Clindamycin is CONTRAINDICATED in patients with severe diarrhoea, as it can aggravate the condition. 

Medications To Avoid With This Drug 

  • Avoid taking Erythromycin with Clindamycin. These can counteract each other’s effects when used together.

Overdose And Missed Dose

  • If you miss a dose of Clindamycin, take it as soon as you remember. But, if the next dose is near, skip the missed dose and resume the regular dosing regime.

Management Of Side Effects

  • Taking Clindamycin with meals can help manage the gastrointestinal side effects of the medicine.

Use In Driving And Operating Machinery

  • It is unlikely to impair the mental alertness or coordination required while driving.

Use In Pregnancy And Lactation

  • Caution is advised for use of Clindamycin in pregnant women and it is not recommended for breastfeeding women.

Caution In Other Conditions

  • It should also be cautiously used by older adults and patients with kidney disease, liver disease, an intestinal disorder such as colitis (inflamed colon) or inflammatory bowel disease (IBD), or a history of asthma, eczema, or allergic skin reaction.

Special Dietary And Lifestyle Recommendation

  • Clindamycin can disrupt the balance of intestinal bacteria; incorporate probiotic-rich foods like yoghurt or probiotic supplements to help maintain healthy gut flora.
  • It's advisable to avoid alcohol consumption while on Clindamycin, as it may increase the risk of gastrointestinal side effects.
  • Maintain a balanced fibre-rich diet to support digestive health and minimise the risk of antibiotic-associated diarrhoea.

Frequently asked questions

Clindamycin may improve the symptoms in 1-3 days, but it is essential to complete the course as prescribed to prevent recurrence of infection and development of antibiotic resistance.

Avoid medications like Erythromycin and neuromuscular blocking agents that may interact with Clindamycin.

Do not stop Clindamycin early; take the medicine till the prescribed duration to ensure the infection is fully treated.

Clindamycin is not habit-forming and is generally safe when used as directed.

It's best to avoid alcohol while taking Clindamycin, as it can increase the risk of side effects.

Clindamycin doesn't typically affect fertility. However, if you are concerned about the effect of this medicine on fertility, consult your doctor for personalised advice.

Clindamycin usually requires a prescription and is not available over the counter.

If you miss a dose of Clindamycin, take it as soon as you remember, but do not double the next dose.

Yes, Clindamycin can cause diarrhea as a side effect. This antibiotic can disrupt the balance of beneficial bacteria in the gut, potentially leading to a condition called antibiotic-associated diarrhea. In some cases, it can lead to a more serious intestinal condition called Clostridium difficile-associated diarrhea.

Clindamycin is considered a potent antibiotic effective against a wide range of bacterial infections. It is particularly strong against anaerobic bacteria and some Gram-positive bacteria, making it a valuable option for treating severe infections that other antibiotics might not effectively address.

The duration for taking Clindamycin safely varies depending on the type and severity of the infection being treated. Typically, it is prescribed for 7 to 14 days. However, it is crucial to follow your healthcare provider's instructions and complete the full course of treatment to ensure the infection is fully eradicated.

Clindamycin should not be used by individuals with a known allergy to it or those who have had a history of colitis or severe diarrhea associated with antibiotic use. Additionally, it should be used with caution in individuals with liver or kidney disease, as these conditions can affect how the medication is processed in the body.

The time it takes for Clindamycin to get rid of an infection depends on the type and severity of the infection. Improvement in symptoms can often be seen within a few days of starting the medication. However, it is important to complete the full prescribed course, typically 7 to 14 days, to ensure the infection is completely treated and to prevent the development of antibiotic resistance.

Terms & Conditions


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