Clindamycin + Nicotinamide
ANTIACNEUses of Clindamycin + Nicotinamide
- Clindamycin and Nicotinamide are commonly used to treat acne and inflammatory skin conditions.
- Clindamycin, an antibiotic, works by penetrating the skin and eliminating acne-causing bacteria, while Nicotinamide reduces inflammation, soothes irritation, and improves skin texture.
- This combination also helps reduce hyperpigmentation and enhances overall skin tone.
Side effects of Clindamycin + Nicotinamide
The side effects of Clindamycin + Nicotinamide are:
- Mild burning
- Itching
- Redness
- Dryness
- Worsening of acne
How Clindamycin + Nicotinamide works
- Clindamycin + Nicotinamide belongs to the group of antibacterial and anti-inflammatory agents, which treat pimples (acne).
- Clindamycin is an antibiotic that inhibits bacterial protein synthesis, thereby preventing the growth and reproduction of certain bacteria. It helps to combat bacterial infections associated with acne.
- Nicotinamide, also known as niacinamide or vitamin B3, exhibits anti-inflammatory properties. It helps reduce the redness, swelling, and inflammation associated with acne. Additionally, nicotinamide regulates the production of sebum, an oily substance produced by the skin. Balancing sebum production helps prevent clogged pores and the formation of acne lesions.
Certified content
Written By
B. Pharm
Reviewed By
B. Pharm, MSc.
Expert Advice
Dosage Forms Available for Clindamycin + Nicotinamide
- Clindamycin + Nicotinamide is applied topically (gel).
Age And Dosage Restrictions for Clindamycin + Nicotinamide
- This combination can be used in adults and children above 12 years of age.
Contraindications of Clindamycin + Nicotinamide
- It is contraindicated in patients with a history of hypersensitivity to clindamycin, nicotinamide, or other lincomycin preparations.
Medications To Avoid With Clindamycin + Nicotinamide
- Avoid taking neuromuscular blocking agents (atracurium) and applying topical antibiotics containing erythromycin and metronidazole. These medications may alter the safety and effectiveness of Clindamycin + Nicotinamide.
Overdose and Missed Dose
- Apply this combination on the affected area as your doctor prescribes. Follow their prescribed dosage and do not exceed it without consulting them.
- You may apply the missed dose of this combination as soon as you remember and continue with your regular dosing schedule.
Management of Side Effects
- The side effects of this combination are temporary and resolve on discontinuation. If side effects worsen or persist, consult your doctor for a possible treatment plan adjustment.
Use In Driving And Operating Machinery
- It is unlikely to impair the mental alertness or coordination required while driving.
Use in Pregnancy and Lactation
- Caution is advised in pregnancy and breastfeeding.
Caution in Other Conditions
- Caution is advised in patients with sensitive skin, Crohn’s disease or ulcerative colitis, and atopic eczema.
Special Dietary & Lifestyle Recommendation
- Apply a broad-spectrum sunscreen before sun exposure, as topical clindamycin may increase sensitivity to sunlight. This precaution helps prevent sunburn and minimises the risk of hyperpigmentation.
- Use non-comedogenic moisturisers to keep the skin hydrated and protected.
- Avoid excessive touching, picking, or squeezing of acne lesions, leading to further inflammation and potential scarring.
- Avoid harsh scrubbing or over-washing, which can irritate the skin and worsen acne.
- Do not apply it to open wounds, cuts, or damaged skin, as it may cause irritation or blood absorption of its ingredients.
Frequently asked questions
1. Does Clindamycin + Nicotinamide effectively remove acne marks?
This combination primarily target active acne by reducing inflammation and controlling bacterial growth. It might not be efficient in removing acne marks or scars. Consult your dermatologist for scar reduction treatment options.
2. Can Clindamycin + Nicotinamide be applied to the face?
Yes, this combination can be applied to the face, but it should be done as per the instructions provided by a doctor or as directed on the product label.
3. Is Clindamycin + Nicotinamide effective for dark spots?
No, this combination is not effective for dark spots. It primarily treats acne vulgaris and its associated symptoms and is not specifically formulated or indicated for removing dark spots or hyperpigmentation. Consult your dermatologist for dark spot treatment options.
4. How long does Clindamycin + Nicotinamide take to work?
Consistent use of this combination may be required for several weeks to observe noticeable improvements. The time it takes for this gel to work can vary depending on individual factors and the severity of the acne condition.
5. Can I drive after applying Clindamycin + Nicotinamide?
This combination is intended for topical application and is not likely to affect your ability to operate machinery or drive a vehicle.
6. Is Clindamycin + Nicotinamide available over the counter, or do I need a prescription?
This combination usually requires a prescription and is unavailable over the counter.
7. Does Clindamycin + Nicotinamide affect fertility?
This combination is applied topically and is not known to affect fertility.
8. Can Clindamycin + Nicotinamide be applied to private parts?
This combination is generally not recommended for application on private parts.
9. Can Clindamycin + Nicotinamide be used as a spot treatment for single pimples?
Yes, Clindamycin + Nicotinamide can be used as a spot treatment for single pimples. Clindamycin helps reduce bacterial growth, while Nicotinamide (Vitamin B3) reduces inflammation and redness.
10. Can Clindamycin + Nicotinamide be used for other skin conditions besides acne?
Yes, Clindamycin + Nicotinamide can be used for other skin conditions such as rosacea and certain inflammatory skin disorders. Both ingredients help reduce inflammation and improve skin appearance.
11. Can Clindamycin + Nicotinamide be used on other parts of the body besides the face?
Yes, Clindamycin + Nicotinamide can be applied to other parts of the body where acne or other skin conditions occur. Ensure to follow instructions and consult a healthcare provider for the best results.
12. Can Clindamycin + Nicotinamide cause skin peeling?
Clindamycin + Nicotinamide may cause mild skin peeling or dryness, especially when you first start using it. If peeling is severe or persistent, consult a healthcare provider.
13. Is Clindamycin + Nicotinamide safe for long-term use?
Clindamycin + Nicotinamide is generally safe for long-term use when used as directed by a healthcare provider. However, long-term use should be monitored to avoid potential side effects like irritation or resistance.
Clindamycin + Nicotinamide in other salts
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