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Clobetasone

Uses of Clobetasone

  • Clobetasone is primarily used to manage various skin conditions, including eczema, dermatitis, psoriasis, insect bites and stings, and nappy rash. It belongs to the group of glucocorticoids, which are classes of corticosteroids.

  • In addition to the primary uses, doctors may sometimes prescribe Clobetasone for other off-label uses based on their medical judgement.

Side effects of Clobetasone

  • Burning or stinging sensation at the application site

  • Itching or redness of the treated skin

  • Skin dryness or irritation

  • Folliculitis (inflammation of hair follicles)

  • Skin thinning or atrophy

How Clobetasone works

  • Clobetasone is a topical corticosteroid.

  • It functions by binding to glucocorticoid receptors in skin cells. By doing this, it regulates gene transcription, leading to a decrease in pro-inflammatory mediators such as cytokines, prostaglandins, and leukotrienes.

  • This action reduces inflammation and adjusts the immune response at the skin level, helping to manage symptoms of various skin conditions.

Certified content

Written By

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Ashmita BorgohainMedical Content Writer & Editor| 12 years

MSc (Applied Genetics)

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • Clobetasone is available for topical use as creams, ointments, and lotions.

Age and Dose Restrictions

  • Clobetasone may be used by both adults and children aged 12 years and over.

Contraindications

  • Clobetasone is contraindicated for individuals with known hypersensitivity to the medication or any of its components. It should not be used on skin that is infected or has untreated bacterial, viral, or fungal infections.

Other Medications to Avoid

  • While Clobetasone does not have significant interactions with other medications when applied topically, it is essential to inform your doctor about any other medications you are taking, including over-the-counter products and supplements.

Overdose and Missed Dose

  • Overdosing on Clobetasone is unlikely due to its topical application. Using the prescribed dosage is recommended to avoid any side effects. However, if you accidentally apply more than recommended, wipe off the excess medication with a clean tissue.

  • If a dose is missed, apply as soon as you remember. But if it is almost time for the next application, skip the missed dose and continue with your regular schedule.

Management of Side Effects

Most side effects of Clobetasone are temporary and generally harmless. They resolve upon discontinuation of the medication. However, if you experience any severe side effects or worsening of symptoms, consult your doctor.

  • To manage itching or irritation at the application site, try applying the medication at different times of day.

  • If you experience dryness where Clobetasone has been applied, consider using a fragrance-free moisturiser after the medication has fully absorbed.

Use in Driving and Operating Machinery

  • Since Clobetasone is a topical medication, it is unlikely to affect your ability to drive or operate machinery.

Use in Pregnancy and Lactation

  • The safety of Clobetasone use during pregnancy and lactation has not been fully established. Therefore, consult your doctor before using this medication if you are pregnant or breastfeeding.

Caution in Other Conditions

  • Caution should be exercised when using Clobetasone on large areas of skin, broken or raw skin, skin folds, and areas of skin that rub together, like under the breasts or between the buttocks. Also, it should not be used on the face unless advised by a doctor.

Special Dietary and Lifestyle Recommendations

  • Avoid scratching your skin even if it itches, as this can lead to further inflammation or infection.

  • Use gentle skincare products that do not irritate the skin.

  • Protect your skin from extreme weather conditions, which may aggravate your skin condition further.

Frequently asked questions

Yes, Clobetasone is a topical corticosteroid medication. It belongs to the class of medications known as glucocorticoids which have potent anti-inflammatory and immunosuppressive properties.

Clobetasone starts working soon after it is applied. It reduces inflammation and itchiness in the affected area, providing relief from skin conditions. However, the exact time it takes to start working may vary based on the severity of your condition.

There are various other topical corticosteroids available that can be used as an alternative to Clobetasone. These include betamethasone, hydrocortisone, and mometasone among others. However, you should only switch to these under the guidance of your doctor.

Clobetasone is unlikely to affect your hormonal balance when used correctly, as it is a topical medication and its absorption into the bloodstream is minimal. However, prolonged or excessive use could potentially lead to systemic effects.

Clobetasone can be used in children under the supervision of a doctor. However, special care should be taken as children's skin tends to absorb larger amounts of topical medication, which could possibly lead to more side effects.

Applying too much Clobetasone may result in more medicine being absorbed into your body, which can cause side effects such as skin thinning and other problems associated with steroid overuse. If you accidentally apply too much, wipe off the excess with a tissue and contact your doctor if you experience any discomfort or unusual symptoms.

Clobetasone should not be used on infected skin or open wounds as this could potentially worsen the infection. If you have a skin infection, consult your doctor for further advice.

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