Dapagliflozin + Linagliptin
Uses of Dapagliflozin + Linagliptin
Dapagliflozin + Linagliptin is primarily used to manage type 2 diabetes in adults and belongs to the group of anti-diabetic medicines.
In addition to its main use, this combination medication helps lower the risk of major adverse cardiovascular events in adults with type 2 diabetes and established cardiovascular disease.
Side effects of Dapagliflozin + Linagliptin
Vaginal yeast infections
Common cold
Urinary tract infections
Increased urination
Upper respiratory tract infection
How Dapagliflozin + Linagliptin works
Dapagliflozin belongs to a group of medicines called sodium-glucose co-transporter 2 (SGLT2) inhibitors. Its job is to stop your kidneys from reabsorbing glucose back into your blood and instead, help you excrete it through your urine. This process ultimately reduces the overall blood sugar levels.
Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor. It works by increasing the levels of substances called incretins in the body, which help to regulate insulin production after meals. These incretins also decrease the amount of sugar made by the liver, helping to further reduce blood glucose levels.
Certified content
Written By
MSc (Applied Genetics)
Reviewed By
BMS, FMC, MD Resident
Expert Advice
Dosage Forms Available
Dapagliflozin + Linagliptin is available in tablet form for oral administration.
Age and Dose Restrictions
This combination medicine is intended for use only in adults and is not recommended for children or adolescents under 18 years of age.
Contraindications
Dapagliflozin + Linagliptin is contraindicated in patients with severe kidney disease or on dialysis.
This medicine should not be used by those with a history of serious hypersensitivity reactions to either dapagliflozin or linagliptin.
Patients with a history of diabetic ketoacidosis should avoid using this combination medication.
Other Medications to Avoid
Dapagliflozin + Linagliptin may interact with diuretics (e.g., furosemide, hydrochlorothiazide), insulin or other medications that control blood sugar (e.g., glipizide and glimepiride).
Overdose and Missed Dose
An overdose of this medication can lead to symptoms such as nausea, vomiting, and dizziness. If suspected, consult your doctor immediately.
If you forget to take a dose of this medicine, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular schedule.
Management of Side Effects
Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.
Drinking plenty of water can help manage some of the side effects like dizziness or lightheadedness.
Taking the medicine with food can help prevent any gastrointestinal issues. However, if you experience any severe side effects or worsening of symptoms, please consult your doctor.
Use in Driving and Operating Machinery
Dapagliflozin + Linagliptin may cause dizziness or fatigue. If you experience these symptoms, avoid driving or operating heavy machinery until you feel well enough.
Use in Pregnancy and Lactation
It is advised not to use this medicine during pregnancy or breastfeeding unless prescribed by your doctor. Always consult your doctor regarding this medication if you're planning to conceive, are pregnant or are breastfeeding.
Caution in Other Conditions
Patients with liver disease, heart problems, infections of the urinary tract or genital area, or a history of low blood pressure should be cautious when using this combination medicine.
This medication should also be used with caution in patients with conditions that may lead to dehydration or a loss of body fluids.
Special Dietary and Lifestyle Recommendations
Regular monitoring of blood sugar levels is important to ensure that the medication is working effectively.
Frequently asked questions
Is Dapagliflozin + Linagliptin a steroid?
No, Dapagliflozin + Linagliptin is not a steroid. It is a combination of a sodium-glucose co-transporter 2 (SGLT 2) inhibitor and a dipeptidyl peptidase-4 (DPP-4) inhibitor.
Does Dapagliflozin + Linagliptin have any effect on sleep?
Dapagliflozin + Linagliptin is not known to have any specific effect on sleep. However, if you experience sleep changes, consult your doctor.
Will Dapagliflozin + Linagliptin affect fertility?
This combination medication does not indicate any effect on fertility; if you have concerns, consult your doctor.
Are there any particular dietary restrictions while taking Dapagliflozin + Linagliptin?
There are no specific dietary restrictions for taking Dapagliflozin + Linagliptin. However, maintaining a balanced diet and following your doctor's recommendations is advised.
Is it safe to take Dapagliflozin + Linagliptin daily?
It is better to take this medicine for the duration recommended by your doctor.
How much time does Dapagliflozin + Linagliptin take to work?
The time frame for Dapagliflozin + Linagliptin to show effects varies by individual and condition severity. For further concerns, it is best to consult your doctor.
Is Dapagliflozin + Linagliptin available over the counter, or do I need a prescription?
Dapagliflozin + Linagliptin is a prescription-based medication and is not available over the counter.
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