Diacerein

Dosage Forms Available

• Diacerein is primarily available in the form of oral capsules.

Age and Dose Restrictions

• Diacerein is intended for use in adults.

Contraindications

• Diacerein is contraindicated in patients with hypersensitivity to diacerein or any components of the formulation. It should be avoided in individuals with severe liver or kidney disease.

Other Medications to Avoid

• Diacerein may interact with diuretics (such as furosemide and hydrochlorothiazide). It should be used cautiously with cardiac glycosides (like digoxin and digitoxin).

Overdose and Missed Dose

• Overdosing on Diacerein can cause an increase in the severity of side effects, particularly gastrointestinal disturbances. If you suspect an overdose, contact your doctor immediately.

• If you miss a dose of Diacerein, take it as soon as you remember. If it is nearly time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not double up on doses to make up for a missed one.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

• For mild gastrointestinal side effects such as diarrhoea or abdominal pain, consider taking the medication with meals.

• Stay hydrated to help manage diarrhoea.

• Ensure adequate rest to manage fatigue or dizziness.

Use in Driving and Operating Machinery

• Diacerein might cause dizziness or fatigue in some individuals. If you experience such symptoms, avoid driving or operating heavy machinery.

Use in Pregnancy and Lactation

• Diacerein is not recommended for use during pregnancy or lactation.

Caution in Other Conditions

• Individuals with liver and kidney diseases should exercise caution while using Diacerein as it might increase the risk of adverse effects. Elderly patients and individuals with inflammatory bowel diseases should also use this medication carefully.

Special Dietary and Lifestyle Recommendations

• Weight control is essential as excess weight can put extra pressure on weight-bearing joints, worsening the symptoms of osteoarthritis.

• Avoid activities that strain affected joints.