Diacewal 50mg Capsules 10

Diacewal 50 Capsule 10

Wallace Pharmaceuticals Ltd.

Strip of 10 Units

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MRP ~~₹148~~

₹73.85

₹14.80/Units

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Composition

Diacerein (50 Mg)

Diacewal 50 Capsule 10 is an oral medication primarily used to manage the symptoms of osteoarthritis, particularly in the hip and knee joints. This medicine belongs to a class of medicine called symptomatic slow-acting medicine (SYSADOA), anthraquinones.

In addition to this primary use, this capsule also significantly slows down the progression of cartilage degradation, thereby helping manage signs and symptoms in patients suffering from osteoarthritis.

Before starting this medication, you must consult your doctor, who will guide you on the correct dosage and frequency based on your condition. Remember to inform your doctor about any pre-existing conditions or ongoing medications you may be taking. If you notice any side effects while on this medicine, notify your doctor immediately. It's important to continue taking the medicine for the duration your doctor prescribes for optimal results.

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Diacewal 50 Capsule 10 can be used for the following:

Alleviating pain and inflammation related to osteoarthritis.
Slowing down the progression of cartilage degradation in osteoarthritis.
Managing symptoms and signs of hip and knee osteoarthritis.

Directions for Use of Diacewal 50 Capsule 10

Take Diacewal 50 Capsule 10 as per the instructions below:

Swallow the capsule whole with a glass of water. Do not chew or crush it.
Always take this medicine during or after meals.
Do not exceed the dosage recommended by your doctor.
Consult your doctor immediately if you miss a dose, but avoid doubling up on doses.
Remember to continue taking this medicine for the duration prescribed by your doctor.

Diacewal 50 Capsule 10 is taken orally.

Diacewal 50 Capsule 10 may have the following common side effects:

Soft stools
Diarrhoea
Abdominal pain
Nausea
Skin rash
Liver function abnormalities: Changes in the way your liver works, which may be detected through blood tests.

Managing the Side Effects:

Most side effects are temporary and generally harmless, which resolve upon discontinuing the use of Diacewal 50 Capsule 10. However, if you experience severe side effects or worsening symptoms, please consult your doctor.

Here are some general guidelines for managing common side effects:

Diarrhoea: Try taking Diacewal 50 Capsule 10 with meals.
Abdominal pain: Consider taking this medicine after meals to lessen this effect.

Diacewal 50 Capsule 10 contains Diacerein (50 mg), which works in your body through several mechanisms:

Inhibits Interleukin-1β System: Diacerein blocks a system in your body known as the Interleukin-1β (IL-1β) system. This system usually causes inflammation.
Reduces Sensitivity to IL-1: This medicine decreases how sensitive your body is to IL-1 by reducing IL-1 receptor levels on certain cells called chondrocytes.
Increases Production of IL-1 Receptor Antagonist: Diacerein indirectly boosts the production of a substance that prevents IL-1 from working effectively.
Suppresses Activation of NF-κB Transcription Factor: Diacerein stops a factor in your body called NF-κB from being activated. This factor usually stimulates the expression of proteins that cause inflammation.
Reduces Cartilage Loss: This medicine helps to reduce the loss of cartilage, a flexible tissue that protects your joints.
Increases Subchondral Bone Mineral Density: Diacerein boosts the mineral density of a part of your bone called the subchondral bone. This action can help make your bones stronger.

Pregnancy

Caution is advised while taking Diacewal 50 Capsule 10 if you are pregnant. It is best to consult your doctor before taking this medicine.

Breastfeeding

If you are breastfeeding, it's important to discuss the use of Diacewal 50 Capsule 10 with your doctor to understand the potential risks and benefits. Do not take it without consulting a doctor.

Alcohol

There is no known interaction between Diacewal 50 Capsule 10 and alcohol. However, it's always a good idea to discuss your alcohol consumption with your doctor when starting a new medicine.

Liver

If you have liver problems, it's advised to talk to your doctor before starting Diacewal 50 Capsule 10. This medicine may affect liver function.

Kidney

Caution is advised before using Diacewal 50 Capsule 10 if you have a history of any kidney problems. It's best to consult your doctor before taking this medicine.

Using Machines & Driving

Diacewal 50 Capsule 10 does not generally affect your ability to drive or operate machinery. However, if you feel unwell after taking the medicine, avoid driving or using heavy machinery until you feel better.

Allergy

If you know that you're allergic to diacerein or any other ingredients in Diacewal 50 Capsule 10, avoid taking this medicine. Always inform your doctor about any allergies before starting a new medication.

Children

Caution is advised while giving Diacewal 50 Capsule 10 to children under 18 years of age. Always consult your doctor before giving any medicine to a child.

Older Patients

Older patients should take Diacewal 50 Capsule 10 under medical supervision as they may be more susceptible to its side effects. Caution is advised if patients are above 70 years of age. Your doctor will guide you based on your health status.

Drug-Drug Interactions

Diacewal 50 Capsule 10 interacts with the following medicines:

CYP2C9 substrates: Medicines like warfarin and phenytoin may interact with Diacewal 50 Capsule 10, potentially increasing their blood levels and risk of toxicity.
CYP3A4 inducers: Medicines such as rifampicin may reduce the bioavailability of Diacewal 50 Capsule 10, potentially lowering its effectiveness.

Drug-Food Interactions

There are no known specific food interactions with Diacewal 50 Capsule 10. However, it is recommended to take this medication with meals.

Drug-Disease Interactions

Diacewal 50 Capsule 10 interacts with the following diseases:

Renal Impairment: The medication should be used cautiously in patients suffering from severe renal impairment as it could pose potential risks.
Hepatic Impairment: People with severe liver disease should exercise caution while taking Diacewal 50 Capsule 10 as it could exacerbate their condition.

Daily Dose

The daily dose of Diacewal 50 Capsule 10 should be taken as directed by your doctor. This may vary based on factors such as the severity of your condition and how well you respond to the medicine. It's crucial to adhere to your prescribed dosage and not exceed it without consulting your doctor.

Over Dose

In the event of an overdose, common side effects may become more pronounced. If you accidentally take more than the prescribed dose, inform your doctor. Do not panic, but let them know so they can provide appropriate guidance.

Missed Dose

If you forget to take a dose of Diacewal 50 Capsule 10, take it as soon as you remember. However, if it's nearly time for your next dose, skip the missed one and continue with your regular schedule. Never increase your dosage without consulting your doctor.

Store Diacewal 50 Capsule 10 at a cool room temperature.
Keep it in a dry place, safe from light and moisture.
Ensure this medication is kept out of the reach of children.
Always check the expiry date on the packet before taking Diacewal 50 Capsule 10.

Engage in regular, gentle exercise such as swimming or cycling. This can help manage symptoms of osteoarthritis by strengthening the muscles around your joints, increasing flexibility, and improving mood.
Maintain a healthy weight to reduce stress on weight-bearing joints like the hips and knees, helping to decrease pain and slow down disease progression. Consult your doctor for specific dietary advice.

Fact Box

Drug Category	Anti-Inflammatory
Therapeutic Category	Osteoarthritis Medication
Available Dosage Types	Capsule
Habit Forming	No
Ailment	Hip Osteoarthritis, Knee Osteoarthritis

What is Diacewal 50 Capsule 10 used for?

Diacewal 50 Capsule 10 is used to manage the symptoms of osteoarthritis, such as pain and inflammation, especially in the hip and knee joints.

How does Diacewal 50 Capsule 10 work?

The active ingredient in Diacewal 50 Capsule 10, diacerein, works by reducing inflammation and slowing down the breakdown of cartilage in your joints.

Can I use Diacewal 50 Capsule 10 as a pain-killer?

No, Diacewal 50 Capsule 10 is not a conventional pain-killer. It helps manage osteoarthritis symptoms, including pain, through its effects on inflammation and cartilage metabolism.

How long does it take for Diacewal 50 Capsule 10 to work?

Diacewal 50 Capsule 10 typically takes about 4-6 weeks to provide significant relief from osteoarthritis symptoms

Can I take Diacewal 50 Capsule 10 with other painkillers?

Yes, you can combine Diacewal 50 Capsule 10 with simple analgesics like paracetamol for additional symptom relief. However, always consult your doctor before doing so.

What if I miss a dose of Diacewal 50 Capsule 10?

If you miss a dose of Diacewal 50 Capsule 10, take it as soon as you remember. But if it's almost time for your next dose, skip the missed one.

Are there any side effects of taking Diacewal 50 Capsule 10?

Mild gastrointestinal disturbances, such as soft stools, abdominal pain, and nausea, are common but usually go away as the body adjusts to the medicine.

Certified Content

Written by

Dr. Michelle Frank

Medical Content Writer | 8 years

Doctor of Medicine

Reviewed by

Dr. Chhavi Rosha

Health & Medical Content Writer | 8 years

BMS, FMC, MD Resident

Check out Editorial Policy

Manufacturer details

T1/B NATIONAL PARKGULBAI TEKRA AHMEDABAD GJ 380015 IN

Country of origin: INDIA

References

Diacerein-containing medicines for oral administration - referral | European Medicines Agency. (n.d.). https://www.ema.europa.eu/en/medicines/human/referrals/diacerein-containing-medicines-oral-administration
Kaur, D., Kaur, J., & Kamal, S. S. (2018). Diacerein, its beneficial impact on chondrocytes and notable new clinical applications. Brazilian Journal of Pharmaceutical Sciences, 54(4). https://doi.org/10.1590/s2175-97902018000417534
OSHA HCS. (2024). Safety Data Sheet (pp. 1–8) [Report]. https://cdn.caymanchem.com/cdn/msds/11710m.pdf
Diacerein: Uses, interactions, mechanism of action | DrugBank Online. (n.d.). DrugBank. https://go.drugbank.com/drugs/DB11994

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