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Drospirenone + Ethinyl Estradiol

Uses of Drospirenone + Ethinyl Estradiol

  • Drospirenone + Ethinyl Estradiol is primarily used as an oral contraceptive to prevent pregnancy in women and belongs to the group of hormonal contraceptives.

  • Additionally, it is also indicated for the management of symptoms of premenstrual dysphoric disorder (PMDD) and moderate acne in women who are at least 14 years old.

Side effects of Drospirenone + Ethinyl Estradiol

  • Headache

  • Nausea

  • Breast tenderness

  • Spotting or bleeding between periods

  • Weight gain

How Drospirenone + Ethinyl Estradiol works

  • Drospirenone + Ethinyl Estradiol is a hormonal contraceptive combination.

  • Drospirenone is a synthetic form of progesterone, a female hormone. It works by preventing the release of an egg from the ovary during the menstrual cycle, which is known as ovulation.

  • Ethinyl Estradiol is a synthetic form of another female hormone, oestrogen. It assists in contraception by thickening the mucus at the entrance of the womb, thus making it more difficult for sperm to enter and reach an egg.

Certified content

Written By

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Dr. Michelle FrankMedical Content Writer| 8 years

Doctor of Medicine

Reviewed By

Dr. Chhavi Rosha
Dr. Chhavi Rosha Health & Medical Content Writer| 8 years

BMS, FMC, MD Resident

Expert Advice

Dosage Forms Available

  • The medicine Drospirenone + Ethinyl Estradiol is available in the form of oral tablets.

Age and Dose Restrictions

  • This medicine is primarily meant for women of child-bearing age for contraceptive and other hormonal purposes.

  • It is not recommended for girls who have not yet begun menstruating.

Contraindications

  • Women with kidney disease or kidney failure should not use this medicine.

  • This medication is also not recommended for women who have adrenal disease, a history of blood clots, stroke, or heart attack.

  • Women with unusual vaginal bleeding, known or suspected pregnancy, liver tumours, liver disease, breast cancer or a history of breast cancer should avoid using this medicine.

Other Medications to Avoid

  • Drospirenone + Ethinyl Estradiol may interact with anticoagulants (such as warfarin, rivaroxaban), anti-seizure medications (such as phenytoin, carbamazepine), and medications affecting liver enzymes (such as ketoconazole, rifampin). It may also interact with antibiotics (such as amoxicillin, doxycycline) and anti-HIV medications (such as ritonavir, efavirenz).

Overdose and Missed Dose

  • Overdosing on Drospirenone + Ethinyl Estradiol may result in nausea and vaginal bleeding. If you suspect an overdose, contact Poison Control immediately.

  • If you miss a dose, take it as soon as you remember unless it is almost time for the next dose. In that case, skip the missed dose and continue with your regular schedule. Never take two doses at once.

Management of Side Effects

Most side effects are temporary and generally harmless and resolve when discontinuing this medicine. However, if you experience any severe side effects or worsening of any of the symptoms, please consult your doctor.

  • Drinking plenty of water may help manage side effects like headaches and nausea.

  • Eating a balanced diet may help manage weight gain associated with this medication.

  • Practicing good sleep hygiene can help manage mood changes associated with this medication.

Use in Driving and Operating Machinery

  • This medication may cause dizziness or tiredness which might impair your ability to drive or operate machinery. If you experience these symptoms, do not drive or operate machinery until you feel well again.

Use in Pregnancy and Lactation

  • Drospirenone + Ethinyl Estradiol should normally not be taken during pregnancy. If pregnancy occurs, the medication should be stopped immediately.

  • It is also not recommended for breastfeeding women, as it may affect milk production.

Caution in Other Conditions

  • Women who have migraines with aura, diabetes-related complications or uncontrolled high blood pressure should exercise caution when taking Drospirenone + Ethinyl Estradiol.

  • Women who smoke and are over 35 years old should exercise caution as well.

Special Dietary and Lifestyle Recommendations

  • Maintain a balanced diet rich in fruits, vegetables, lean proteins and whole grains to support overall health.

  • Regular physical activity will contribute to maintaining a healthy weight and overall well-being.

  • Limit intake of alcoholic beverages as they may elevate blood pressure and interfere with the effectiveness of this medication.

  • Refrain from smoking as it can increase the risk of cardiovascular issues while taking this medication.

Frequently asked questions

Yes, the tablets of Drospirenone + Ethinyl Estradiol are typically vegetarian-friendly. However, it is always advisable to check the product label or consult your doctor for the same.

Yes, some women might experience mood changes while using Drospirenone + Ethinyl Estradiol as a side effect. If you notice any significant change in your mood, consult your doctor.

No, there is no known risk of dependency or withdrawal with Drospirenone + Ethinyl Estradiol.

Specific food interactions with Drospirenone + Ethinyl Estradiol are not typically a concern; however, you should avoid grapefruit and grapefruit juice as it could potentially interact with this medication.

Yes, weight gain can be a common side effect for some women taking Drospirenone + Ethinyl Estradiol.

Yes, Drospirenone + Ethinyl Estradiol can cause changes in menstrual cycles such as spotting or bleeding between periods.

If you are allergic to Drospirenone + Ethinyl Estradiol, other hormonal contraceptives may be an option for you. It is important to consult your doctor to determine the best alternative for you.

Terms & Conditions


Available medicines for DROSPIRENONE + ETHINYL ESTRADIOL
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Dronis 30 Tablet 21
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Dronis 20 Tablet 24
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